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Objective: Traumatic brain injuries and damage are major causes of death and disability. We propose a 3D fully coupled electro-mechanical model of a nerve bundle to investigate the electrophysiological impairments due to trauma at the…

Biological Physics · Physics 2020-09-02 Ilaria Cinelli , Michel Destrade , Maeve Duffy , Peter McHugh

Brain mechanics is a topic of deep interest because of the significant role of mechanical cues in both brain function and form. Specifically, capturing the heterogeneous and anisotropic behaviour of cerebral white matter (WM) is extremely…

Soft Condensed Matter · Physics 2021-10-20 Asad Jamal , Andrea Bernardini , Daniele Dini

Brain injuries are a major reason for mortality and morbidity following trauma in sports, work and traffic. Apart from the trauma at the site of impact (coup injury), other regions of the brain remote from the impact locations (non-coup)…

Quantitative Methods · Quantitative Biology 2020-12-02 Rajesh Kumar , Md Zubair , Sudipto Mukherjee , Jacobo Antona Makoshi

The strain-rate sensitivity of confined granular materials has been widely explored, with most findings exhibiting rate-strengthening behaviors. This study, however, reveals a distinct rate-softening behavior across a certain strain rate…

Soft Condensed Matter · Physics 2024-05-01 Mingchao Liu , Weining Mao , Yiqiu Zhao , Qin Xu , Yixiang Gan , Yifan Wang , K Jimmy Hsia

The saturation level of the magnetorotational instability (MRI) is investigated using three-dimensional MHD simulations. The shearing box approximation is adopted and the vertical component of gravity is ignored, so that the evolution of…

Astrophysics · Physics 2009-11-10 Takayoshi Sano , Shu-ichiro Inutsuka , Neal J. Turner , James M. Stone

We use a global magnetohydrodynamic simulation of a geometrically thin accretion disk to investigate the locality and detailed structure of turbulence driven by the magnetorotational instability (MRI). The model disk has an aspect ratio $H…

High Energy Astrophysical Phenomena · Physics 2015-05-28 Kris Beckwith , Philip J. Armitage , Jacob B. Simon

Background: Transcranial magnetic stimulation (TMS) is a powerful tool to investigate neurophysiology of the human brain and treat brain disorders. Traditionally, therapeutic TMS has been applied in a one-size-fits-all approach,…

In comparative and developmental neuroanatomy one encounters questions regarding the deformation of neural tissue under stress. The motivation of this note is an observation (Barbas {\it et al}) that at cortical folds or gyri, the layers of…

Tissues and Organs · Quantitative Biology 2007-05-23 Partha P. Mitra

Mild traumatic brain injury is a growing public health problem with an estimated incidence of over 1.7 million people annually in US. Diagnosis is based on clinical history and symptoms, and accurate, concrete measures of injury are…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Shervin Minaee , Yao Wang , Anna Choromanska , Sohae Chung , Xiuyuan Wang , Els Fieremans , Steven Flanagan , Joseph Rath , Yvonne W Lui

Ramp compression experiments characterize high-pressure states of matter at temperatures well below those present in shock compression. However, because temperature is typically not directly measured during ramp compression, it is uncertain…

Materials Science · Physics 2021-10-14 F. González-Cataldo , B. K. Godwal , Kevin Driver , Raymond Jeanloz , Burkhard Militzer

Twisted bilayer graphene (TBG) has drawn significant interest due to recent experiments which show that TBG can exhibit strongly correlated behavior such as the superconducting and correlated insulator phases. Much of the theoretical work…

Mathematical Physics · Physics 2025-05-23 Tianyu Kong , Alexander B. Watson , Mitchell Luskin , Kevin D. Stubbs

Vehicle safety systems have substantially decreased motor vehicle crash-related injuries and fatalities, but injuries to the lumbar spine still have been reported. Experimental and computational analyses of upright and, particularly,…

Flux-pinning-induced stress and strain distributions in a thin disk superconductor in a perpendicular magnetic field is analyzed. We calculate the body forces, solve the magneto-elastic problem and derive formulas for all stress and strain…

Superconductivity · Physics 2007-05-23 Tom H. Johansen , Daniel V. Shantsev

Silicon carbide is a hard, semiconducting material presenting many polytypes, whose behavior under extreme conditions of pressure and temperature has attracted large interest. Here we study the mechanical properties of 3C-SiC over a wide…

Materials Science · Physics 2023-07-20 Carlos P. Herrero , Rafael Ramirez , Gabriela Herrero-Saboya

Functional behavior of NiTi shape memory alloys is restricted to temperatures below 150 {\deg}C. To shed light on the origin of the loss of functional properties of NiTi with increasing temperature, we have investigated stress induced…

Materials Science · Physics 2024-06-24 O. Tyc , E. Iaparova , O. Molnárová , L. Heller , P. Šittner

Shock compression of silicon (Si) under extremely high pressures (>100 Mbar) was investigated by using two first-principles methods of orbital-free molecular dynamics (OFMD) and path integral Monte Carlo (PIMC). While pressures from the two…

Materials Science · Physics 2016-12-21 S. X. Hu , B. Militzer , L. A. Collins , K. P. Driver , J. D. Kress

Blunt traumatic aortic rupture is a heart injury that can occur in falls, automobile accidents, and sporting injuries involving impact to the thorax. Despite its severity and high morbidity rate, the research still does not provide a…

We characterize the amplitude statistics of intraoperative microelectrode recordings (MERs) obtained during deep brain stimulation (DBS) surgery in 46 patients with Parkinson's disease, using 184 recordings equally balanced between inside…

Tissues commonly consist of cells embedded within a fibrous biopolymer network. Whereas cell-free reconstituted biopolymer networks typically soften under applied uniaxial compression, various tissues, including liver, brain, and fat, have…

A central challenge in the computational modeling of neural dynamics is the trade-off between accuracy and simplicity. At the level of individual neurons, nonlinear dynamics are both experimentally established and essential for neuronal…