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Machine learning is increasingly used to guide branch-and-cut (B&C) for mixed-integer linear programming by learning score-based policies for selecting branching variables and cutting planes. Many approaches train on local signals from…

Optimization and Control · Mathematics 2026-02-02 Hongyu Cheng , Amitabh Basu

There exist several methods dealing with the reconstruction of rooted phylogenetic networks explaining different evolutionary histories given by rooted binary phylogenetic trees. In practice, however, due to insufficient information of the…

Populations and Evolution · Quantitative Biology 2015-12-18 Benjamin Albrecht

Here we show that deciding whether two rooted binary phylogenetic trees on the same set of taxa permit a cherry-picking sequence, a special type of elimination order on the taxa, is NP-complete. This improves on an earlier result which…

Populations and Evolution · Quantitative Biology 2021-04-13 Janosch Döcker , Leo van Iersel , Steven Kelk , Simone Linz

Phylogenetic networks play an important role in evolutionary biology as, other than phylogenetic trees, they can be used to accommodate reticulate evolutionary events such as horizontal gene transfer and hybridization. Recent research has…

Populations and Evolution · Quantitative Biology 2024-03-19 Linda Knüver , Mareike Fischer , Marc Hellmuth , Kristina Wicke

Here we present a new fixed parameter tractable algorithm to compute the hybridization number r of two rooted, not necessarily binary phylogenetic trees on taxon set X in time (6^r.r!).poly(n)$, where n=|X|. The novelty of this approach is…

Quantitative Methods · Quantitative Biology 2012-07-26 Teresa Piovesan , Steven Kelk

Here we present a new fixed parameter tractable algorithm to compute the hybridization number r of two rooted binary phylogenetic trees on taxon set X in time (6r)^r.poly(n), where n=|X|. The novelty of this approach is that it avoids the…

Populations and Evolution · Quantitative Biology 2011-08-24 Steven Kelk

Phylogenetic reconciliation seeks to explain host-symbiont co-evolution by mapping parasite trees onto host trees through events such as cospeciation, duplication, host switching, and loss. Finding an optimal reconciliation that ensures…

Populations and Evolution · Quantitative Biology 2026-02-02 Cyriac Antony , Alessio Martino , Blerina Sinaimeri

Phylogenetic networks have gained prominence over the years due to their ability to represent complex non-treelike evolutionary events such as recombination or hybridization. Popular combinatorial objects used to construct them are triplet…

Combinatorics · Mathematics 2016-10-19 P. Gambette , K. T. Huber , S. Kelk

The robustness of deep neural networks is crucial to modern AI-enabled systems and should be formally verified. Sigmoid-like neural networks have been adopted in a wide range of applications. Due to their non-linearity, Sigmoid-like…

Machine Learning · Computer Science 2022-08-31 Zhaodi Zhang , Yiting Wu , Si Liu , Jing Liu , Min Zhang

With the development of connected filters for the last decade, many algorithms have been proposed to compute the max-tree. Max-tree allows to compute the most advanced connected operators in a simple way. However, no fair comparison of…

Computer Vision and Pattern Recognition · Computer Science 2013-01-11 Edwin Carlinet , Thierry Géraud

We consider the problem of optimally compressing and caching data across a communication network. Given the data generated at edge nodes and a routing path, our goal is to determine the optimal data compression ratios and caching decisions…

Networking and Internet Architecture · Computer Science 2018-01-25 Jian Li , Faheem Zafari , Don Towsley , Kin K. Leung , Ananthram Swami

Rooted phylogenetic networks are used to describe evolutionary histories that contain non-treelike evolutionary events such as hybridization and horizontal gene transfer. In some cases, such histories can be described by a phylogenetic…

Populations and Evolution · Quantitative Biology 2016-10-03 Laura Jetten , Leo van Iersel

We give a 2-approximation algorithm for Non-Uniform Sparsest Cut that runs in time $n^{O(k)}$, where $k$ is the treewidth of the graph. This improves on the previous $2^{2^k}$-approximation in time $\poly(n) 2^{O(k)}$ due to Chlamt\'a\v{c}…

Data Structures and Algorithms · Computer Science 2013-05-08 Anupam Gupta , Kunal Talwar , David Witmer

The recently introduced graph parameter tree-cut width plays a similar role with respect to immersions as the graph parameter treewidth plays with respect to minors. In this paper, we provide the first algorithmic applications of tree-cut…

Data Structures and Algorithms · Computer Science 2022-06-03 Robert Ganian , Eun Jung Kim , Stefan Szeider

In this paper we consider the problem of computing an mRNA sequence of maximal similarity for a given mRNA of secondary structure constraints, introduced by Backofen et al. in [BNS02] denoted as the MRSO problem. The problem is known to be…

Data Structures and Algorithms · Computer Science 2007-05-23 Frank Gurski

We seek to develop network algorithms for function computation in sensor networks. Specifically, we want dynamic joint aggregation, routing, and scheduling algorithms that have analytically provable performance benefits due to in-network…

Networking and Internet Architecture · Computer Science 2012-06-25 Siddhartha Banerjee , Piyush Gupta , Sanjay Shakkottai

An instance of the Connected Maximum Cut problem consists of an undirected graph G = (V, E) and the goal is to find a subset of vertices S $\subseteq$ V that maximizes the number of edges in the cut \delta(S) such that the induced graph…

Data Structures and Algorithms · Computer Science 2015-07-03 MohammadTaghi Hajiaghayi , Guy Kortsarz , Robert MacDavid , Manish Purohit , Kanthi Sarpatwar

Here we show that, given a set of clusters C on a set of taxa X, where |X|=n, it is possible to determine in time f(k).poly(n) whether there exists a level-<= k network (i.e. a network where each biconnected component has reticulation…

Computational Complexity · Computer Science 2011-08-19 Steven Kelk , Celine Scornavacca

Phylogenetic comparative methods (PCMs) are widely used to study trait evolution. However, many evolutionary histories involve reticulate evolutionary scenarios, such as hybridization, that violate core assumptions of these methods. In this…

Populations and Evolution · Quantitative Biology 2026-03-30 Lydia Morley , Emma Lehmberg , Sungsik Kong

Phylogenetic networks are a generalization of phylogenetic trees allowing for the representation of non-treelike evolutionary events such as hybridization. Typically, such networks have been analyzed based on their `level', i.e. based on…

Populations and Evolution · Quantitative Biology 2020-05-11 Mareike Fischer , Michelle Galla , Lina Herbst , Yangjing Long , Kristina Wicke