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We study a discrete-time interacting particle system with continuous state space which is motivated by a mathematical model for turnover through branching in actin filament networks. It gives rise to transient clusters reminiscent of actin…

Probability · Mathematics 2024-10-01 Cecilia González-Tokman , Dietmar B. Oelz

The emergence of macroscopic order and patterns is a central paradigm in systems of (self-)propelled agents, and a key component in the structuring of many biological systems.The relationships between the ordering process and the underlying…

Soft Condensed Matter · Physics 2020-12-02 Jonas Denk , Erwin Frey

A unique pattern selection in the absolutely unstable regime of driven, nonlinear, open-flow systems is reviewed. It has recently been found in numerical simulations of propagating vortex structures occuring in Taylor-Couette and…

patt-sol · Physics 2009-10-30 P. Buechel , M. Luecke

We study a nonlinear transport equation defined on an oriented network where the velocity field depends not only on the state variable, but also on the solution itself. We prove existence, uniqueness and continuous dependence results for…

Analysis of PDEs · Mathematics 2018-04-04 Fabio Camilli , Raul De Maio , Andrea Tosin

A high degree of control over the structure and dynamics of domain patterns in nonequilibrium systems can be achieved by applying nonuniform external fields near parity breaking front bifurcations. An external field with a linear spatial…

patt-sol · Physics 2009-10-28 A. Hagberg , E. Meron , I. Rubinstein , B. Zaltzman

Quantifying the influence of microscopic details on the dynamics of development of the overall structure of a filamentous network is important in a number of biologically relevant contexts, but it is not obvious what order parameters can be…

Biological Physics · Physics 2021-01-04 Yossi Eliaz , Francois Nedelec , Greg Morrison , Herbert Levine , Margaret S. Cheung

This paper proposes methods for identification of large-scale networked systems with guarantees that the resulting model will be contracting -- a strong form of nonlinear stability -- and/or monotone, i.e. order relations between states are…

Systems and Control · Electrical Eng. & Systems 2021-08-02 Max Revay , Jack Umenberger , Ian R. Manchester

We study the stochastic dynamics of growth and shrinkage of single actin filaments taking into account insertion, removal, and ATP hydrolysis of subunits either according to the vectorial mechanism or to the random mechanism. In a previous…

Biomolecules · Quantitative Biology 2015-05-13 Padinhateeri Ranjith , Kirone Mallick , Jean-Francois Joanny , David Lacoste

We propose an optimal control approach in order to identify the nonlinearity in the monodomain model, from given data. This data-driven approach gives an answer to the problem of selecting the model when studying phenomena related to…

Optimization and Control · Mathematics 2022-09-22 Sebastien Court , Karl Kunisch

Myosin II molecular motors slide actin filaments relatively to each other and are essential for force generation, motility and mechanosensing in animal cells. For non-muscle cells, evolution has resulted in three different isoforms, which…

Cell Behavior · Quantitative Biology 2025-08-28 Nils O. Winkler , Oliver M. Drozdowski , Falko Ziebert , Ulrich S. Schwarz

Cellular actin structures are continuously turned over while keeping similar sizes. Since they all compete for a shared pool of actin monomers, the question arises how they can coexist in these dynamic steady states. Recently, the…

Subcellular Processes · Quantitative Biology 2026-04-27 Valentin Wössner , Falko Ziebert , Ulrich S. Schwarz

Migration of animal cells is based on the interplay between actin polymerization at the front, adhesion along the cell-substrate interface, and actomyosin contractility at the back. Active gel theory has been used before to demonstrate that…

Cell Behavior · Quantitative Biology 2024-12-11 Valentin Wössner , Oliver M. Drozdowski , Falko Ziebert , Ulrich S. Schwarz

The equilibrium distributions of a Markovian model describing the interaction of several classes of permanent connections in a network are analyzed. It has been introduced by Graham and Robert. For this model each of the connections has a…

Networking and Internet Architecture · Computer Science 2015-05-13 Carl Graham , Philippe Robert , Maaike Verloop

We study a continuum model of dislocation transport in order to investigate the formation of heterogeneous dislocation patterns. We propose a physical mechanism which relates the formation of heterogeneous patterns to the dynamics of a…

Materials Science · Physics 2018-08-29 Ronghai Wu , Daniel Tüzes , Péter Dusán Ispánovity , István Groma , Michael Zaiser

For a general class of translationally invariant systems with a specific category of nonlinearity in the output, this paper presents necessary and sufficient conditions for global observability. Critically, this class of systems cannot be…

Dynamical Systems · Mathematics 2022-10-11 Eduardo D. Sontag , Debojyoti Biswas , Noah J. Cowan

We develop an agent-based model of the motion and pattern formation of vesicles. These intracellular particles can be found in four different modes of (undirected and directed) motion and can fuse with other vesicles. While the size of…

Subcellular Processes · Quantitative Biology 2011-09-19 Mirko Birbaumer , Frank Schweitzer

A class of systems is considered, where immobile species associated to distinct patches, the nodes of a network, interact both locally and at a long-range, as specified by an (interaction) adjacency matrix. Non local interactions are…

Pattern Formation and Solitons · Physics 2020-06-30 Giulia Cencetti , Federico Battiston , Timoteo Carletti , Duccio Fanelli

Biological functions rely on ordered structures and intricately controlled collective dynamics. In contrast to systems in thermodynamic equilibrium, order is typically established and sustained in stationary states by continuous dissipation…

We find a statistical mechanism that can adjust orientations of intracellular filaments to cell geometry in absence of organizing centers. The effect is based on random and isotropic filament (de-)polymerization dynamics and is independent…

Biological Physics · Physics 2015-05-28 Philip Greulich , Ludger Santen

Cytoplasmic dyneins transport cellular organelles by moving on a microtubule filament. It has been found recently that depending on the applied force and the concentration of the adenosine triphosphate (ATP) molecules, dynein's step size…

Statistical Mechanics · Physics 2009-11-13 Sutapa Mukherji