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Optical tweezers are highly versatile laser traps for neutral microparticles, with fundamental applications in physics and in single molecule cell biology. Force measurements are performed by converting the stiffness response to…

Optics · Physics 2014-06-30 R S Dutra , N B Viana , P A Maia Neto , H M Nussenzveig

Optically levitated dielectric nanoparticles have become valuable tools for precision sensing and quantum optomechanical experiments. To predict the dynamic properties of a particle trapped in an optical tweezer with high fidelity, a tool…

Optics · Physics 2024-11-20 Moosung Lee , Tobias Hanke , Sara Launer , Sungkun Hong

How far a particle moves along the optical axis in a holographic optical trap is not simply dictated by the programmed motion of the trap, but rather depends on an interplay of the trap's changing shape and the particle's material…

Soft Condensed Matter · Physics 2019-10-02 Michael J. O'Brien , David G. Grier

Optical tweezers (OT) have become an essential technique in several fields of physics, chemistry, and biology as precise micromanipulation tools and microscopic force transducers. Quantitative measurements require the accurate calibration…

The viscous drag on a colloidal particle pulled through solution by an optical trap is large enough that on experimentally relavant time scales the mechanical force exerted by the trap is equal and op- posite the viscous drag force. The…

Statistical Mechanics · Physics 2007-05-23 R. Dean Astumian

The forces acting on an optically trapped particle are usually assumed to be conservative. However, the presence of a non-conservative component has recently been demonstrated. Here we propose a technique that permits one to quantify the…

Statistical Mechanics · Physics 2010-02-08 Giuseppe Pesce , Giorgio Volpe , Anna Chiara De Luca , Giulia Rusciano , Giovanni Volpe

Optical tweezers find applications in various fields, ranging from biology to physics. One of the fundamental steps necessary to perform quantitative measurements using trapped particles is the calibration of the tweezer's spring constant.…

Quantum Physics · Physics 2020-06-05 Bruno Melo , Felipe Almeida , Guilherme Temporão , Thiago Guerreiro

Experiment, theory, and simulation are employed to understand the dispersion of colloidal particles in a periodic array of oscillating harmonic traps generated by optical tweezers. In the presence of trap oscillation, a non-monotonic and…

Soft Condensed Matter · Physics 2023-01-18 Joseph M. Barakat , Sho C. Takatori

In this work we show that two absorbing microbeads can briefly share the same optical trap. Optical forces pull the particles towards the waist of the trapping beam. However, once a particle reaches the vicinity of the waist, the…

Optics · Physics 2016-09-14 Viridiana Carmona-Sosa , Pedro A. Quinto-Su

Experimental observations suggest that there are differences between the behavior of particles optically trapped in air and trapped in a liquid phase. We present a modified version of Mie Debye Spherical Aberration theory to numerically…

Optics · Physics 2015-05-19 D. R. Burnham , D. McGloin

Optical tweezers equipped with position detection allow for application of piconewton-scale forces and high-temporal-resolution measurements of nanometer-scale motion. While typically used for trapping microscopic objects, the optical…

A macroscopic characterization of fractals showing up a structural transition from dense to multibranched growth is made using optical diffraction theory. Such fractals are generated via the numerical solution of the 2D Poisson and…

Condensed Matter · Physics 2009-10-22 F. Perez-Rodriguez , Wei Wang , E. Canessa

Critical Casimir forces emerge between objects, such as colloidal particles, whenever their surfaces spatially confine the fluctuations of the order parameter of a critical liquid used as a solvent. These forces act at short but…

Soft Condensed Matter · Physics 2020-08-05 Agnese Callegari , Alessandro Magazzù , Andrea Gambassi , Giovanni Volpe

Bayesian inference provides a principled way of estimating the parameters of a stochastic process that is observed discretely in time. The overdamped Brownian motion of a particle confined in an optical trap is generally modelled by the…

Data Analysis, Statistics and Probability · Physics 2017-02-01 Sudipta Bera , Shuvojit Paul , Rajesh Singh , Dipanjan Ghosh , Avijit Kundu , Ayan Banerjee , R. Adhikari

Computational modelling has made many useful contributions to the field of optical tweezers. One aspect in which it can be applied is the simulation of the dynamics of particles in optical tweezers. This can be useful for systems with many…

Optical and acoustical trapping has been established as a tool for holding and moving microscopic particles suspended in a liquid in a contact-free and non-invasive manner. Opposed to standard microscopic imaging where the probe is fixated,…

Numerical Analysis · Mathematics 2025-10-27 Peter Elbau , Monika Ritsch-Marte , Otmar Scherzer , Denise Schmutz

Optical trapping, where microscopic particles are trapped and manipulated by light is a powerful and widespread technique, with the single-beam gradient trap (also known as optical tweezers) in use for a large number of biological and other…

Optics · Physics 2007-05-23 T. A. Nieminen , H. Rubinsztein-Dunlop , N. R. Heckenberg

We demonstrate photophoretic force-based optical trapping of multiple absorbing particles in air by loosely focusing a Gaussian beam with a series of convex lenses of different focal lengths, and investigate the dependence of the number of…

Optics · Physics 2022-06-15 Souvik Sil , Anita Pahi , Aman Anil Punse , Ayan Banerjee

Optical tweezers enable non-contact trapping of micro-scale objects using light. Despite their widespread use, it is currently not known how tightly it is possible to three-dimensionally trap micro-particles with a given photon budget.…

Optical tweezers are widely used as a highly sensitive tool to measure forces on micron-scale particles. One such application is the measurement of the electric charge of a particle, which can be done with high precision in liquids, air, or…

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