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Cardiometabolic diseases have substantially increased in China in the past 20 years and blood pressure is a primary modifiable risk factor. Using data from the China Health and Nutrition Survey, we examine blood pressure trends in China…
Medical studies for chronic disease are often interested in the relation between longitudinal risk factor profiles and individuals' later life disease outcomes. These profiles may typically be subject to intermediate structural changes due…
The association between visit-to-visit systolic blood pressure variability and cardiovascular events has recently received a lot of attention in the cardiovascular literature. But blood pressure variability is usually estimated on a…
Continuous and noninvasive monitoring of blood pressure has numerous clinical and fitness applications. Current methods of continuous measurement of blood pressure are either invasive and/or require expensive equipment. Therefore, we…
Hypertension is a highly prevalent condition and a major risk factor for cardiovascular disease. The landmark Systolic Blood Pressure Intervention Trial (SPRINT) showed that lowering systolic blood pressure (BP) goals from 140 mmHg to 120…
This study develops a Bayesian semi-parametric model to examine the longitudinal growth and appetite phenotypes in children from the GUSTO cohort, with a focus on understanding the relationship between eating behaviours and growth outcomes…
Blood Pressure (BP) is a biological signal related to the cardiovascular system that inevitably is affected by ageing. Moreover, it is also influenced by the presence of cardiovascular risk factors. To evaluate how the relationship be-tween…
Motivated by two case studies using primary care records from the Clinical Practice Research Datalink, we describe statistical methods that facilitate the analysis of tall data, with very large numbers of observations. Our focus is on…
This study examined the flow rate in arteries using the modified Windkessel model, considering various models for blood pressure. An exact solution was derived using a Laplace transform method and the effects of blood pressure on the flow…
The prevalence of chronic non-communicable diseases such as obesity has noticeably increased in the last decade. The study of these diseases in early life is of paramount importance in determining their course in adult life and in…
A model for cross-over designs with repeated measures within each period was developed. It is obtained using an extension of generalized estimating equations that includes a parametric component to model treatment effects and a…
Detection and monitoring of patients with pulmonary hypertension, defined as mean blood pressure in the main pulmonary artery above 25 mmHg, requires a combination of imaging and hemodynamic measurements. This study demonstrates how to…
The influence of hypertension on low-density lipoproteins intake into the arterial wall is an important factor for understanding mechanisms of atherosclerosis. It has been experimentally observed that the increased pressure leads to the…
Given the high incidence of cardio and cerebrovascular diseases (CVD), and its association with morbidity and mortality, its prevention is a major public health issue. A high level of blood pressure is a well-known risk factor for these…
In the attention-deficit hyperactivity disorder (ADHD) study, children are prescribed different stimulant medications. The height measurements are recorded longitudinally along with the medication time. Differences among the patients are…
Alcohol misuse is a key target of public health strategies aimed at reducing cardiovascular risk. The effect of excessive alcohol consumption on blood pressure may vary systematically with individuals' unobserved propensity to engage in…
Joint models for a wide class of response variables and longitudinal measurements consist on a mixed-effects model to fit longitudinal trajectories whose random effects enter as covariates in a generalized linear model for the primary…
We describe the multiresolution wavelet analysis of blood pressure waves in vasovagal syncope-affected patients compared with those in healthy people, using Haar and Gaussian bases. A comparison between scale-dependent and scale-independent…
Accurate and generalizable blood pressure (BP) estimation is vital for the early detection and management of cardiovascular diseases. In this study, we enforce subject-level data splitting on a public multi-wavelength photoplethysmography…
This study investigates the relationship between longitudinal serum creatinine measurements and the risk of adverse kidney outcomes in paediatric patients with auto-immune disorders at Great Ormond Street Hospital for Children NHS…