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Artificial intelligence (AI) systems increasingly achieve expert-level predictive accuracy in healthcare, yet improvements in model performance often fail to produce corresponding gains in patient outcomes. We term this disconnect the…

Artificial Intelligence · Computer Science 2026-01-13 Rifa Ferzana

The potential presented by Artificial Intelligence (AI) for healthcare has long been recognised by the technical community. More recently, this potential has been recognised by policymakers, resulting in considerable public and private…

Artificial Intelligence · Computer Science 2021-04-15 Jessica Morley , Caroline Morton , Kassandra Karpathakis , Mariarosaria Taddeo , Luciano Floridi

Artificial intelligence (AI) holds great promise for supporting clinical trials, from patient recruitment and endpoint assessment to treatment response prediction. However, deploying AI without safeguards poses significant risks,…

Machine Learning · Computer Science 2025-10-09 Yao Chen , David Ohlssen , Aimee Readie , Gregory Ligozio , Ruvie Martin , Thibaud Coroller

Artificial Intelligence (AI) is poised to transform healthcare delivery through revolutionary advances in clinical decision support and diagnostic capabilities. While human expertise remains foundational to medical practice, AI-powered…

Screening patients for clinical trial eligibility remains a manual, time-consuming, and resource-intensive process. We present a secure, scalable proof-of-concept system for Artificial Intelligence (AI)-augmented patient-trial matching that…

Artificial Intelligence (AI) in healthcare holds great potential to expand access to high-quality medical care, whilst reducing overall systemic costs. Despite hitting the headlines regularly and many publications of proofs-of-concept,…

Computers and Society · Computer Science 2021-08-06 David Higgins , Vince I. Madai

Artificial Intelligence (AI) holds great promise for transforming healthcare, particularly in disease diagnosis, prognosis, and patient care. The increasing availability of digital medical data, such as images, omics, biosignals, and…

Artificial Intelligence · Computer Science 2025-10-17 Pedro A. Moreno-Sánchez , Javier Del Ser , Mark van Gils , Jussi Hernesniemi

Medical imaging plays a vital role in modern diagnostics; however, interpreting high-resolution radiological data remains time-consuming and susceptible to variability among clinicians. Traditional image processing techniques often lack the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Melika Filvantorkaman , Maral Filvan Torkaman

The impact of using artificial intelligence (AI) to guide patient care or operational processes is an interplay of the AI model's output, the decision-making protocol based on that output, and the capacity of the stakeholders involved to…

The integration of Artificial Intelligence in the development of computer systems presents a new challenge: make intelligent systems explainable to humans. This is especially vital in the field of health and well-being, where transparency…

Traditional AI-based healthcare systems often rely on single-modal data, limiting diagnostic accuracy due to incomplete information. However, recent advancements in foundation models show promising potential for enhancing diagnosis…

Artificial Intelligence · Computer Science 2025-03-24 Sihan Wang , Suiyang Jiang , Yibo Gao , Boming Wang , Shangqi Gao , Xiahai Zhuang

The increasing deployment of artificial intelligence (AI) in clinical settings challenges foundational assumptions underlying traditional frameworks of medical evidence. Classical statistical approaches, centered on randomized controlled…

Methodology · Statistics 2026-01-07 Richik Chakraborty

There is a growing need to understand how digital systems can support clinical decision-making, particularly as artificial intelligence (AI) models become increasingly complex and less human-interpretable. This complexity raises concerns…

Comparative diagnostic in brain tumor evaluation makes possible to use the available information of a medical center to compare similar cases when a new patient is evaluated. By leveraging Artificial Intelligence models, the proposed system…

Image and Video Processing · Electrical Eng. & Systems 2024-05-31 Guillermo Iglesias , Edgar Talavera , Jesús Troya Garcìa , Alberto Díaz-Álvarez , Miguel Gracía-Remesal

Artificial Intelligence (AI) systems are now an integral part of multiple industries. In clinical research, AI supports automated adverse event detection in clinical trials, patient eligibility screening for protocol enrollment, and data…

Artificial Intelligence · Computer Science 2025-12-10 Laxmiraju Kandikatla , Branislav Radeljic

The recent advancements in artificial intelligence (AI) combined with the extensive amount of data generated by today's clinical systems, has led to the development of imaging AI solutions across the whole value chain of medical imaging,…

Regulatory frameworks for the use of AI are emerging. However, they trail behind the fast-evolving malicious AI technologies that can quickly cause lasting societal damage. In response, we introduce a pioneering Assistive AI framework…

Conventional automated decision-support systems often prioritize predictive accuracy, overlooking the complexities of real-world settings where stakeholders' preferences may diverge or conflict. This can lead to outcomes that disadvantage…

Machine Learning · Computer Science 2025-11-25 Vittoria Vineis , Giuseppe Perelli , Gabriele Tolomei

This study empirically examines the "Evaluative AI" framework, which aims to enhance the decision-making process for AI users by transitioning from a recommendation-based approach to a hypothesis-driven one. Rather than offering direct…

Human-Computer Interaction · Computer Science 2024-11-14 Jaroslaw Kornowicz

The competency of any intelligent agent is bounded by its formal account of the world in which it operates. Clinical AI lacks such an account. Existing frameworks address evaluation, regulation, or system design in isolation, without a…

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