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Parkinson's disease (PD) is a common neurological disorder characterized by gait impairment. PD has no cure, and an impediment to developing a treatment is the lack of any accepted method to predict disease progression rate. The primary aim…

Signal Processing · Electrical Eng. & Systems 2019-11-26 Vyom Raval , Kevin P. Nguyen , Ashley Gerald , Richard B. Dewey , Albert Montillo

In this work we propose a stochastic differential equation (SDE) for modelling health related quality of life (HRQoL) over a lifespan. HRQoL is assumed to be bounded between 0 and 1, equivalent to death and perfect health, respectively.…

Methodology · Statistics 2023-06-14 Ralph Brinks

We first show (1) the importance of investigating health expenditure process using the order two Markov chain model, rather than the standard order one model, which is widely used in the literature. Markov chain of order two is the minimal…

Econometrics · Economics 2018-01-29 Taiyo Fukai , Hidehiko Ichimura , Kyogo Kanazawa

Public health researchers often estimate health effects of exposures (e.g., pollution, diet, lifestyle) that cannot be directly measured for study subjects. A common strategy in environmental epidemiology is to use a first-stage (exposure)…

Methodology · Statistics 2014-06-03 Adam A. Szpiro , Christopher J. Paciorek

We propose a new model for comprehensively monitoring the health status of individuals by calculating a personal health index. The central framework of the model is the International Classification of Functioning, Disability and Health…

Computers and Society · Computer Science 2023-04-14 Ilkka Rautiainen , Lauri Parviainen , Veera Jakoaho , Sami Äyrämö , Jukka-Pekka Kauppi

Keeping the health condition at the juvenile population is the concern of both the medical staff and the physical education teachers. Considering the steady tendency of the growth of the number of the youth with excessive weight…

Computers and Society · Computer Science 2009-03-04 Tiberiu Marius Karnyanszky , Corina Musuroi , Carla Amira Karnyanszky

Age-dependent dynamics is an important characteristic of many infectious diseases. Age-group epidemic models describe the infection dynamics in different age-groups by allowing to set distinct parameter values for each. However, such models…

Methodology · Statistics 2017-07-17 Rami Yaari , Itai Dattner , Amit Huppert

Understanding age-group dynamics of infectious diseases is a fundamental issue for both scientific study and policymaking. Age-structure epidemic models were developed in order to study and improve our understanding of these dynamics. By…

Populations and Evolution · Quantitative Biology 2019-11-22 Rami Yaari , Amit Huppert , Itai Dattner

As cancer patient survival improves, late effects from treatment are becoming the next clinical challenge. Chemotherapy and radiotherapy, for example, potentially increase the risk of both morbidity and mortality from second malignancies…

This study introduces a novel method for predicting cognitive age using psychophysiological tests. To determine cognitive age, subjects were asked to complete a series of psychological tests measuring various cognitive functions, including…

Neurons and Cognition · Quantitative Biology 2025-12-29 Daria D. Tyurina , Sergey V. Stasenko , Konstantin V. Lushnikov , Maria V. Vedunova

Recent studies on modelling the progression of Alzheimer's disease use a single modality for their predictions while ignoring the time dimension. However, the nature of patient data is heterogeneous and time dependent which requires models…

Computers and Society · Computer Science 2021-10-19 Sofia Lahrichi , Maryem Rhanoui , Mounia Mikram , Bouchra El Asri

Degradation data are considered for assessing reliability in highly reliable systems. The usual assumption is that degradation units come from a homogeneous population. But in presence of high variability in the manufacturing process, this…

Methodology · Statistics 2026-01-15 Barin Karmakar , Biswabrata Pradhan

Dynamic microsimulation has long been recognized as a powerful tool for policy analysis, but in fact most major health policy simulations lack path dependency, a critical feature for evaluating policies that depend on accumulated outcomes…

Applications · Statistics 2025-06-04 Adrienne M. Propp , Raffaele Vardavas , Carter C. Price , Kandice A. Kapinos

Rehabilitation is essential and critical for post-stroke patients, addressing both physical and cognitive aspects. Stroke predominantly affects older adults, with 75% of cases occurring in individuals aged 65 and older, underscoring the…

Computer Vision and Pattern Recognition · Computer Science 2025-02-28 Jisoo Lee , Tamim Ahmed , Thanassis Rikakis , Pavan Turaga

Fatigue is a broad, multifactorial concept that includes the subjective perception of reduced physical and mental energy levels. It is also one of the key factors that strongly affect patients' health-related quality of life. To date, most…

Human-Computer Interaction · Computer Science 2021-08-10 Yang Bai , Yu Guan , Jian Qing Shi , Wan-Fai Ng

In many countries life expectancy gains have been substantially higher than predicted by even recent forecasts. This is primarily due to increasing rates of improvement in old-age mortality not captured by existing models. In this paper we…

Methodology · Statistics 2021-09-07 Søren Fiig Jarner

This study develops a methodology by capturing both the battery aging state and degradation rate for improved life prediction performance. The aging state is indicated by six physical features of an equivalent circuit model that are…

Machine Learning · Computer Science 2023-08-29 Mingyuan Zhao , Yongzhi Zhang

Recently, we have shown that the age-specific prevalence of a disease can be related to the transition rates in the illness-death model via a partial differential equation (PDE). In case of a chronic disease, we show that the PDE can be…

Populations and Evolution · Quantitative Biology 2017-12-29 Ralph Brinks

Modeling how individuals evolve over time is a fundamental problem in the natural and social sciences. However, existing datasets are often cross-sectional with each individual observed only once, making it impossible to apply traditional…

Machine Learning · Computer Science 2019-03-06 Emma Pierson , Pang Wei Koh , Tatsunori Hashimoto , Daphne Koller , Jure Leskovec , Nicholas Eriksson , Percy Liang

This paper generalizes a previously published differential equation that describes the relation between the age-specific incidence, remission, and mortality of a disease with its prevalence. The underlying model is a simple compartment…

Populations and Evolution · Quantitative Biology 2012-09-07 Ralph Brinks