Related papers: Application of Data mining in Protein sequence Cla…
In this paper, we generalize image (texture) statistical descriptors and propose algorithms that improve their efficacy. Recently, a new method showed how the popular Co-Occurrence Matrix (COM) can be modified into a fuzzy version (FCOM)…
Protein fitness optimization involves finding a protein sequence that maximizes desired quantitative properties in a combinatorially large design space of possible sequences. Recent advances in steering protein generative models (e.g.,…
Deep generative models that learn from the distribution of natural protein sequences and structures may enable the design of new proteins with valuable functions. While the majority of today's models focus on generating either sequences or…
Proteins are essential for life, and their structure determines their function. The protein secondary structure is formed by the folding of the protein primary structure, and the protein tertiary structure is formed by the bending and…
We show that protein sequences can be thought of as sentences in natural language processing and can be parsed using the existing Quantum Natural Language framework into parameterized quantum circuits of reasonable qubits, which can be…
Protein-ligand scoring is an important step in a structure-based drug design pipeline. Selecting a correct binding pose and predicting the binding affinity of a protein-ligand complex enables effective virtual screening. Machine learning…
Thermostability is an important prerequisite for enzymes employed for industrial applications. Several machine learning based models have thus been formulated for protein classification based on this particular trait. These models have…
Fingerprint classification is an effective technique for reducing the candidate numbers of fingerprints in the stage of matching in automatic fingerprint identification system (AFIS). In recent years, deep learning is an emerging technology…
Neural networks and deep learning are changing the way that artificial intelligence is being done. Efficiently choosing a suitable network architecture and fine-tune its hyper-parameters for a specific dataset is a time-consuming task given…
Emergences of computers and information technological revolution made tremendous changes in the real world and provides a different dimension for the intelligent data analysis. Well formed fact, the information at right time and at right…
The representational capacity of modern neural network architectures has made them a default choice in various applications with high dimensional feature sets. But these high dimensional and potentially noisy features combined with the…
Decision tree is an important method for both induction research and data mining, which is mainly used for model classification and prediction. ID3 algorithm is the most widely used algorithm in the decision tree so far. In this paper, the…
The work presents an extension of the fuzzy approach to 2-D shape recognition [1] through refinement of initial or coarse classification decisions under a two pass approach. In this approach, an unknown pattern is classified by refining…
A widespread approach in machine learning to evaluate the quality of a classifier is to cross -- classify predicted and actual decision classes in a confusion matrix, also called error matrix. A classification tool which does not assume…
Enzymes and proteins are live driven biochemicals, which has a dramatic impact over the environment, in which it is active. So, therefore, it is highly looked-for to build such a robust and highly accurate automatic and computational model…
The Gene or DNA sequence in every cell does not control genetic properties on its own; Rather, this is done through translation of DNA into protein and subsequent formation of a certain 3D structure. The biological function of a protein is…
The classification of amino acids and their sequence analysis plays a vital role in life sciences and is a challenging task. This article uses and compares state-of-the-art deep learning models like convolution neural networks (CNN), long…
A fundamental goal of research in molecular biology is to understand protein structure. Protein crystallography is currently the most successful method for determining the three-dimensional (3D) conformation of a protein, yet it remains…
Deep learning approaches have produced substantial breakthroughs in fields such as image classification and natural language processing and are making rapid inroads in the area of protein design. Many generative models of proteins have been…
Protein-protein interaction (PPI) networks, providing a comprehensive landscape of protein interacting patterns, enable us to explore biological processes and cellular components at multiple resolutions. For a biological process, a number…