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We study an infection-age structured epidemic model in which both the infectivity and the rate of loss of immunity depend on the time-since-infection. The model can be equivalently viewed as a nonlinear renewal equation for the incidence of…

Dynamical Systems · Mathematics 2025-11-13 Francesca Scarabel , Harry Coldwell , Tyler Cassidy

This paper describes a novel approach to modeling homphily, i.e. the tendency of nodes that share (or differ in) certain attributes to be linked; we consider dynamic networks in which nodes can be added over time but not removed. Our…

Genomics · Quantitative Biology 2022-01-13 V. DeGruttola , M. Nakazawa , J. Liu , X. Tu , S. Little , S. Mehta

Chronic infections of the human immunodeficiency virus (HIV) create a very complex co-evolutionary process, where the virus tries to escape the continuously adapting host immune system. Quantitative details of this process are largely…

Populations and Evolution · Quantitative Biology 2022-07-27 Andrea Mazzolini , Thierry Mora , Aleksandra M Walczak

In this work, we study the dynamics of a spatially heterogeneous single population model with the memory effect and nonlinear boundary condition. By virtue of the implicit function theorem and Lyapunov-Schmidt reduction, spatially…

Dynamical Systems · Mathematics 2024-03-25 Quanli Ji , Ranchao Wu , Tonghua Zhang

A stochastic model, describing the growth of two competing infections on $\mathbb{R}^d$, is introduced. The growth is driven by outbursts in the infected region, an outburst in the type 1 (2) infected region transmitting the type 1 (2)…

Probability · Mathematics 2015-09-24 Maria Deijfen , Olle Häggström , Jonathan Bagley

Human Papillomaviruses (HPV) are one of the most prevalent sexually transmitted infections (STI) and the most oncogenic viruses known to humans. The vast majority of HPV infections clear in less than 3 years, but the underlying mechanisms,…

Populations and Evolution · Quantitative Biology 2021-09-30 Thomas Beneteau , Christian Selinger , Mircea T. Sofonea , Samuel Alizon

The Susceptible-Infected-Recovered (SIR) model is the cornerstone of epidemiological models. However, this specification depends on two parameters only, which implies a lack of flexibility and the difficulty to replicate the volatile…

Populations and Evolution · Quantitative Biology 2020-11-17 Christian Gourieroux , Yang Lu

This paper carries out an analysis of the global properties of solutions of an in-host model of hepatitis C for general values of its parameters. A previously unknown stable steady state on the boundary of the positive orthant is exhibited.…

Populations and Evolution · Quantitative Biology 2022-06-13 Alexis Nangue , Alan D. Rendall

A theoretical analysis of two- and three-dimensional fractional-order Hindmarsh-Rose neuronal models is presented, focusing on stability properties and occurrence of Hopf bifurcations, with respect to the fractional order of the system…

Dynamical Systems · Mathematics 2017-06-08 Eva Kaslik

In a collection of particles performing independent random walks on $\mathbb Z^d$ we study the spread of an infection with SIR dynamics. Susceptible particles become infected when they meet an infected particle. Infected particles heal and…

Probability · Mathematics 2022-09-14 Duncan Dauvergne , Allan Sly

The coexistence of different viral strains (quasispecies) within the same host are nowadays observed for a growing number of viruses, most notably HIV, Marburg and Ebola, but the conditions for the formation and survival of new strains have…

Populations and Evolution · Quantitative Biology 2008-01-20 Franco Bagnoli , Pietro Lio' , Luca Sguanci

Genetic variations in the COVID-19 virus are one of the main causes of the COVID-19 pandemic outbreak in 2020 and 2021. In this article, we aim to introduce a new type of model, a system coupled with ordinary differential equations (ODEs),…

Analysis of PDEs · Mathematics 2022-03-29 Xiaoqian Gong , Benedetto Piccoli

In this paper, we investigate the effect of dispersal and advection on the dynamics of a predator-prey model. More precisely, we show that the linear stability of the semi-trivial steady state is determined by the dispersal rate, the…

Analysis of PDEs · Mathematics 2023-01-05 Qi Wang

In this paper we investigate a structured population model with distributed delay. Our model incorporates two different types of nonlinearities. Specifically we assume that individual growth and mortality are affected by scramble…

Analysis of PDEs · Mathematics 2023-07-18 Dandan Hu , József Z. Farkas , Gang Huang

Equipment sharing among people who inject drugs (PWID) is a key risk factor in infection by hepatitis C virus (HCV). Both the effectiveness and cost-effectiveness of interventions aimed at reducing HCV transmission in this population (such…

Contemporary epidemiological models often involve spatial variation, providing an avenue to investigate the averaged dynamics of individual movements. In this work, we extend a recent model by Vaziry, Kolokolnikov, and Kevrekidis [Royal…

Populations and Evolution · Quantitative Biology 2024-10-01 Maryam Ahmadpoortorkamani , Alexei Cheviakov

We investigate an epidemiological model that incorporates waning of immunity at the individual level and boosting of the immune system upon re-exposure to the pathogen. When immunity is fully restored upon boosting, the system can be…

Dynamical Systems · Mathematics 2025-08-05 Francesca Scarabel , Mónika Polner , Daniel Wylde , Maria Vittoria Barbarossa , Gergely Röst

We consider two approaches to study the spread of infectious diseases within a spatially structured population distributed in social clusters. According whether we consider only the population of infected individuals or both populations of…

Probability · Mathematics 2007-10-30 Lamia Belhadji

In this article, we present a bifurcation and stability analysis on the double-diffusive convection. The main objective is to study 1) the mechanism of the saddle-node bifurcation and hysteresis for the problem, 2) the formation, stability…

Atmospheric and Oceanic Physics · Physics 2010-05-14 Chun-Hsiung Hsia , Tian Ma , Shouhong Wang

Mathematical models of glucose, insulin, and pancreatic $\beta$-cell mass dynamics are essential for understanding the physiological basis of type 2 diabetes. This paper investigates the Topp model's discrete-time dynamics to represent…

Dynamical Systems · Mathematics 2024-05-02 Z. S. Boxonov , U. A. Rozikov