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We study a bi-virus susceptible-infected-susceptible (SIS) epidemic model in which individuals are either susceptible or infected with one of two virus strains, and consider mutation-driven transitions between strains. The general case of…

Populations and Evolution · Quantitative Biology 2025-10-03 Urmee Maitra , Ashish R. Hota , Vaibhav Srivastava

We study the emergence of symmetric oscillatory behavior in multi-agent systems where each agent incorporates a continuous memory of its past states and past rates of change, modeled by distributed retarded and neutral delays. The…

Dynamical Systems · Mathematics 2026-04-23 Casey Crane

This article proposes a non-autonomous mathematical model with delay for confrontation between two countries, and examines the stability of its equilibrium state. Our criteria for stability take into account the influence of the factor of…

Dynamical Systems · Mathematics 2026-05-14 Teresa Faria , Anatoliy A. Martynyuk

Multiple viruses are widely studied because of their negative effect on the health of host as well as on whole population. The dynamics of coinfection is important in this case. We formulated a SIR model that describes the coinfection of…

Dynamical Systems · Mathematics 2019-05-14 Samia Ghersheen , Vladimir Kozlov , Vladimir G. Tkachev , Uno Wennergren

As the global HIV pandemic enters its fourth decade, increasing numbers of surveillance sites have been established which allows countries to look into the epidemics at a finer scale, e.g. at sub-national level. However, the epidemic models…

Applications · Statistics 2014-11-18 Le Bao , Mary Mahy , Xiaoyue Niu , Tim Brown , Peter Ghys

The existence and local stability of some non-negative equilibrium points of a class of SIRS infectious disease models with non-linear infection and treatment rates are investigated under the condition that the total population is a…

Dynamical Systems · Mathematics 2024-03-08 Mengqi Tan

We propose a population model for TB-HIV/AIDS coinfection transmission dynamics, which considers antiretroviral therapy for HIV infection and treatments for latent and active tuberculosis. The HIV-only and TB-only sub-models are analyzed…

Optimization and Control · Mathematics 2015-04-16 Cristiana J. Silva , Delfim F. M. Torres

We consider a general mathematical model of a within-host viral infection with $n$ virus strains and explicit age-since-infection structure for infected cells. In the model, multiple virus strains compete for a population of target cells.…

Populations and Evolution · Quantitative Biology 2014-05-28 Cameron J. Browne

Neural field models with transmission delay may be cast as abstract delay differential equations (DDE). The theory of dual semigroups (also called sun-star calculus) provides a natural framework for the analysis of a broad class of delay…

Dynamical Systems · Mathematics 2017-12-11 Stephan A. van Gils , Sebastiaan G. Janssens , Yuri A. Kuznetsov , Sid Visser

In this paper, the SIR dynamics is extended by considering another compartmental which represents hospitalization of the critical cases. So a system of differential equations with four blocks is considered when there is intensive care unit…

Populations and Evolution · Quantitative Biology 2023-01-11 Arash Roostaei , Hadi Barzegar , Fakhteh Ghanbarnejad

This paper investigates the effect of drug treatment on the standard within-host HIV model, assuming that therapy occurs periodically. It is shown that eradication is possible under these periodic regimes, and we quantitatively characterize…

Other Quantitative Biology · Quantitative Biology 2008-01-30 Patrick De Leenheer

We consider a stochastic model, describing the growth of two competing infections on $\mathbb{R}^d$. The growth takes place by way of spherical outbursts in the infected region, an outburst in the type 1 (2) infected region causing all…

Probability · Mathematics 2015-09-24 Maria Deijfen , Olle Häggström

This paper investigates a class of reaction-diffusion population models defined on a bounded domain, characterized by a general time-delayed per capita growth rate and a general advection term. Notably, the growth rate encompasses both…

Dynamical Systems · Mathematics 2025-12-04 Jingxiao Song , Chengwei Ren , Shaofen Zou

In this paper, an epidemic model with spatial dependence is studied and results regarding its stability and numerical approximation are presented. We consider a generalization of the original Kermack and McKendrick model in which the size…

Numerical Analysis · Mathematics 2022-04-05 Bálint Takács , Yiannis Hadjimichael

In this study, we develop and analyze a nested multi-scale model for COVID -19 disease that integrates within-host scale and between-host scale sub-models. First, the well-posedness of the multi-scale model is discussed, followed by the…

Dynamical Systems · Mathematics 2021-08-30 Bishal Chhetri , D. K. K Vamsi , Carani Sanjeevi

Multiple mechanisms in the HIV lifecycle play a role in its ability to evade therapy and become a chronic, difficult-to-treat infection. Within its major cellular target, the activated T cell, many steps occur between viral entry and viral…

Cell Behavior · Quantitative Biology 2017-12-04 Jayodita C. Sanghvi , Don Mai , Adam P. Arkin , David V. Schaffer

In this paper we study a nonlinear infection viral propagation model with diffusion, in which, the left boundary is fixed and with homogeneous Dirichlet boundary conditions, while the right boundary is free. We find that the habitat always…

Analysis of PDEs · Mathematics 2024-05-24 Mingxin Wang

We investigate the dynamics of the hepatitis B virus by integrating variable-order calculus and discrete analysis. Specifically, we utilize the Caputo variable-order difference operator in this study. To establish the existence and…

Populations and Evolution · Quantitative Biology 2024-05-27 Meriem Boukhobza , Amar Debbouche , Lingeshwaran Shangerganesh , Delfim F. M. Torres

Dynamic models have been successfully used in producing estimates of HIV epidemics at national level, due to their epidemiological nature and their ability to simultaneously estimate prevalence, incidence, and mortality rates. Recently, HIV…

Methodology · Statistics 2016-02-19 Le Bao , Ben Sheng , Xiaoyue Niu , Yuan Tang , Tim Brown , Peter D. Ghys , Jeff W. Eaton

This study develops and analyzes a stochastic differential equation (SDE) model for the dynamics of hepatitis B virus (HBV) infection. While deterministic frameworks have yielded important insights into viral behavior, they cannot…

Dynamical Systems · Mathematics 2025-10-03 Abdallah Alsammani