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The rapidly developing research field of organic analogue sensors aims to replace traditional semiconductors with naturally occurring materials. Photosensors, or photodetectors, change their electrical properties in response to the light…

Emerging Technologies · Computer Science 2020-03-18 Alexander E. Beasley , Anna L. Powell , Andrew Adamatzky

The mammalian cortex is divided into architectonic and functionally distinct areas. There is growing experimental evidence that their emergence and development is controlled by both epigenetic and genetic factors. The latter were recently…

Neurons and Cognition · Quantitative Biology 2007-05-23 Jan Karbowski , G. B. Ermentrout

Plant phenotyping (Guo et al. 2021; Pieruschka et al. 2019) focuses on studying the diverse traits of plants related to the plants' growth. To be more specific, by accurately measuring the plant's anatomical, ontogenetical, physiological…

Machine Learning · Computer Science 2022-01-17 Jun Wu , Elizabeth A. Ainsworth , Sheng Wang , Kaiyu Guan , Jingrui He

This paper investigates the dynamics of immune response and autoimmunity with particular emphasis on the role of regulatory T cells (Tregs), T cells with different activation thresholds, and cytokines in mediating T cell activity. Analysis…

Quantitative Methods · Quantitative Biology 2019-05-01 F. Fatehi , Y. N. Kyrychko , R. Molchanov , K. B. Blyuss

In this paper, it was revealed by means of methods of atomic force microscopy and magnetic force microscopy that the biogenic magnetic nanoparticles are localized in the form of chains in the walls of the capillaries of animals and the…

Tissues and Organs · Quantitative Biology 2018-11-19 Svitlana Gorobets , Oksana Gorobets , Yuri Gorobets , Maryna Bulaievska

Neuropeptides, members of a large and evolutionarily ancient family of proteinaceous cell-cell signaling molecules, are widely recognized as extremely potent regulators of brain function and behavior. At the cellular level, neuropeptides…

Neurons and Cognition · Quantitative Biology 2020-04-20 Stephen J. Smith , Michael Hawrylycz , Jean Rossier , Uygar Sümbül

Living cells exhibit an important out-of-equilibrium mechanical activity, mainly due to the forces generated by molecular motors. These motor proteins, acting individually or collectively on the cytoskeleton, contribute to the violation of…

Biological Physics · Physics 2009-01-21 Francois Gallet , Delphine Arcizet , Pierre Bohec , Alain Richert

Many water soluble polymers are chemically modified versions of insoluble base materials such as cellulose. A Flory-Huggins model is solved to determine the effects of heterogeneity in modification on the solubility of such polymers. It is…

Soft Condensed Matter · Physics 2009-11-13 Patrick B. Warren

Over the past decade, advances in super-resolution microscopy and particle-based modeling have driven an intense interest in investigating spatial heterogeneity at the level of single molecules in cells. Remarkably, it is becoming clear…

Molecular Networks · Quantitative Biology 2013-11-19 Andrew Mugler , Pieter Rein ten Wolde

A coupled map is suggested to investigate various spatial or temporal designs in biology: Several cells (or tissues) in an organ are considered as connected to each other in terms of some molecular diffusions or electrical potential…

General Physics · Physics 2011-06-07 Caglar Tuncay

Cell polarization relies on long-range cortical flows, which are driven by active stresses and resisted by the cytoskeletal network. While the general mechanisms that contribute to cortical flows are known, a quantitative understanding of…

Soft Condensed Matter · Physics 2023-10-18 Yuqing Qiu , Elizabeth D. White , Edwin M. Munro , Suriyanarayanan Vaikuntanathan , Aaron R. Dinner

In this letter, we analyze a genetic toggle switch recently studied in the literature where the expression of two repressor proteins can be tuned by controlling two different inputs, namely the concentration of two inducer molecules in the…

Molecular Networks · Quantitative Biology 2020-03-18 Davide Fiore , Agostino Guarino , Mario di Bernardo

We model evolution of plants in a world, made up of different locations, with multiple environments (mutually exclusive and collectively exhaustive subsets of locations). Each environment (landmass) has temperature, rainfall, and other…

Populations and Evolution · Quantitative Biology 2019-05-27 Alexander , Khazatsky , Albert Yu , Zihao Zhao , Gabe Zuckerman

The ability of cells to sense and respond to the mechanical properties of their environments is fundamental to a range of cellular behaviours, with substrate stiffness increasingly being found to be a key signalling factor. Although active…

Cell Behavior · Quantitative Biology 2019-09-04 Carina M. Dunlop

An important part of the analysis of bio-molecular networks is to detect different functional units. Different functions are reflected in a different evolutionary dynamics, and hence in different statistical characteristics of network…

Molecular Networks · Quantitative Biology 2007-05-23 Johannes Berg , Michael Lässig

Living plants, while contributing to ecological balance and climate regulation, also function as natural sensors capable of transmitting information about their internal physiological states and surrounding conditions. This rich source of…

Machine Learning · Computer Science 2025-07-01 Eduard Buss , Till Aust , Heiko Hamann

Cell signaling, gene expression, and metabolism are affected by cell-cell heterogeneity and random changes in the environment. The effects of such fluctuations on cell signaling and gene expression have recently been studied intensively…

Biological Physics · Physics 2015-04-02 A. -K. Gustavsson , C. B. Adiels , B. Mehlig , M. Goksör

In this paper, we present a spatial version of phytoplankton-zooplankton model that includes some important factors such as external periodic forces, noise, and diffusion processes. The spatially extended phytoplankton-zooplankton system is…

Populations and Evolution · Quantitative Biology 2008-05-23 Quan-Xing Liu , Bai-Lian Li , Zhen Jin

Dynamic functional connectivity, as measured by the time-varying covariance of neurological signals, is believed to play an important role in many aspects of cognition. While many methods have been proposed, reliably establishing the…

Methodology · Statistics 2019-10-30 Lingge Li , Dustin Pluta , Babak Shahbaba , Norbert Fortin , Hernando Ombao , Pierre Baldi

The human organism is an integrated network where complex physiologic systems, each with its own regulatory mechanisms, continuously interact, and where failure of one system can trigger a breakdown of the entire network. Identifying and…

Data Analysis, Statistics and Probability · Physics 2012-03-02 Amir Bashan , Ronny P. Bartsch , Jan W. Kantelhardt , Shlomo Havlin , Plamen Ch. Ivanov