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A new approach to the modular, complex systems analysis of nonlinear dynamics in cell cycling network transformations involved in carcinogenesis is proposed. Carcinogenesis is a complex process that involves dynamically inter-connected…

Molecular Networks · Quantitative Biology 2007-05-23 V. I. Prisecaru , I. C. Baianu

Microscale fluid flows generated by ensembles of beating eukaryotic flagella are crucial to fundamental processes such as development, motility and sensing. Despite significant experimental and theoretical progress, the underlying physical…

Soft Condensed Matter · Physics 2014-03-11 Douglas R. Brumley , Kirsty Y. Wan , Marco Polin , Raymond E. Goldstein

Eukaryotic cells and intracellular pathogens such as bacteria or viruses utilize the actin polymerization machinery to propel themselves forward. Thereby, the onset of motion and choice of direction may be the result of a spontaneous…

Soft Condensed Matter · Physics 2009-09-04 Karin John , Denis Caillerie , Philippe Peyla , Mourad Ismail , Annie Raoult , Jacques Prost

Biological cells sense and respond to mechanical forces, but how such a mechanosensing proccess takes place in a nonlinear inhomogeneous fibrous matrix remains unknown. We show that cells in a fibrous matrix induce deformation fields that…

Biological Physics · Physics 2015-06-10 Jacob Notbohm , Ayelet Lesman , Phoebus Rosakis , David A. Tirrell , Guruswami Ravichandran

We present a theory of pattern formation in growing domains inspired by biological examples of tissue development. Gradients of signaling molecules regulate growth, while growth changes these graded chemical patterns by dilution and…

Follicle-stimulating hormone (FSH) is produced in the pituitary and is essential for reproduction. It specifically binds to a membrane receptor (FSHR) expressed in somatic cells of the gonads. The FSH/FSHR system presents many peculiarities…

During tissue development, patterns of gene expression determine the spatial arrangement of cell types. In many cases, gradients of secreted signaling molecules - morphogens - guide this process. The continuous positional information…

Molecular Networks · Quantitative Biology 2017-02-08 Ruben Perez-Carrasco , Pilar Guerrero , James Briscoe , Karen Page

Post-transductional modifications tune the functions of proteins and regulate the collective dynamics of biochemical networks that determine how cells respond to environmental signals. For example, protein phosphorylation and nitrosylation…

Cell Behavior · Quantitative Biology 2009-11-13 Roberto Chignola , Chiara Dalla Pellegrina , Alessio Del Fabbro , Edoardo Milotti

We review the recent developments in the field of photonic lattices emphasizing their unique properties for controlling linear and nonlinear propagation of light. We draw some important links between optical lattices and photonic crystals…

Many eukaryotic and prokaryotic cells can exhibit remarkable sensing ability under small gradient of chemical compound. In this study, we approach this phenomenon by considering the contribution of multiple ligands to the chemical kinetics…

Biological Physics · Physics 2013-05-30 Shu-Hao Liou , Chia-Chu Chen

Many studies have shown that cells use temporal dynamics of signalling molecules to encode information. One particular class of temporal dynamics is persistent and transient signals, i.e. signals of long and short durations respectively. It…

Molecular Networks · Quantitative Biology 2018-11-09 Chun Tung Chou

The more we learn about the cytoplasm of cells, the more we realise that the cytoplasm is not uniform but instead is highly inhomogeneous. In any inhomogeneous solution, there are concentration gradients, and particles move either up or…

Subcellular Processes · Quantitative Biology 2019-04-03 Richard P. Sear

To illustrate the power of the biophysical approach in solving important problems in life science, I present here one of our current research projects as an example. We have developed special biophotonic techniques to study the dynamic…

Biological Physics · Physics 2014-01-10 Donald C. Chang

Fractional photon-assisted tunnelling is investigated both numerically and analytically in a double-well lattice. While integer photon-assisted tunnelling is a single-particle effect, fractional photon-assisted tunnelling is an…

Quantum Gases · Physics 2012-02-02 Martin Esmann , Jonathan D. Pritchard , Christoph Weiss

This paper shows that differentiating the lifetimes of two phenotypes independently from their fertility can lead to a qualitative change in the equilibrium of a population: since survival and reproduction are distinct functional aspects of…

Populations and Evolution · Quantitative Biology 2013-05-22 Ignacio Gallo

In this paper we present a derivation and multiscale analysis of a mathematical model for plant cell wall biomechanics that takes into account both the microscopic structure of a cell wall coming from the cellulose microfibrils and the…

Analysis of PDEs · Mathematics 2016-01-01 Mariya Ptashnyk , Brian Seguin

The fast Fourier transform, FFT, is a useful and prevalent algorithm in signal processing. It characterizes the spectral components of a signal, or is used in combination with other operations to perform more complex computations such as…

Signal Processing · Electrical Eng. & Systems 2017-11-08 Hani Nejadriahi , David HillerKuss , Jonathan K. George , Volker J. Sorger

Fluctuation theorems (FTs) quantify the thermodynamic reversibility of a system, and for deterministic systems they are defined in terms of the dissipation function. However, in a nonequilibrium steady state of deterministic dynamics, the…

Statistical Mechanics · Physics 2026-03-24 Stephen Sanderson , Charlotte F. Petersen , Debra J. Searles

The fate of many-body localization in long-range interacting systems is not fully settled. For instance, the phase boundary between ergodic and many-body localized regimes is still under debate. Here, we use Floquet dynamics which can…

Quantum Physics · Physics 2023-02-14 Rozhin Yousefjani , Sougato Bose , Abolfazl Bayat

The sunflower equation describes the motion of the tip of a plant due to the auxin transportation under the influence of gravity. This work proposes the fractional-order generalization to this delay differential equation. The equation…

Dynamical Systems · Mathematics 2024-07-04 Deepa Gupta , Sachin Bhalekar
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