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The evolution of multicellularity was a major transition in the history of life on earth. Conditions under which multicellularity is favored have been studied theoretically and experimentally. But since the construction of a multicellular…

Populations and Evolution · Quantitative Biology 2018-03-19 Jason Olejarz , Kamran Kaveh , Carl Veller , Martin A. Nowak

The outcome of competition among species is influenced by the spatial distribution of species and effects such as demographic stochasticity, immigration fluxes, and the existence of preferred habitats. We introduce an individual-based model…

Populations and Evolution · Quantitative Biology 2010-07-19 Simone Pigolotti , Massimo Cencini

Cell sorting, whereby a heterogeneous cell mixture segregates and forms distinct homogeneous tissues, is one of the main collective cell behaviors at work during development. Although differences in interfacial energies are recognized to be…

Soft Condensed Matter · Physics 2022-07-15 Marc Durand

Experimental studies of cell motility in culture have shown that under adequate conditions these living organisms possess the ability to organize themselves into complex structures. Such structures may exhibit a synergy that greatly…

Statistical Mechanics · Physics 2021-10-27 G. Nakamura , M. Badoual , E. Fabiani , C. Deroulers

Diffusion models accomplish remarkable success in data generation tasks across various domains. However, the iterative sampling process is computationally expensive. Consistency models are proposed to learn consistency functions to map from…

Machine Learning · Computer Science 2025-05-07 Yiding Chen , Yiyi Zhang , Owen Oertell , Wen Sun

Spatial self-organization emerges in distributed systems exhibiting local interactions when nonlinearities and the appropriate propagation of signals are at work. These kinds of phenomena can be modeled with different frameworks, typically…

Cell Behavior · Quantitative Biology 2016-11-23 Adriano Bonforti , Salva Duran-Nebreda , Raul Montañez , Ricard Solé

We compare and contrast the long-time dynamical properties of two individual-based models of biological coevolution. Selection occurs via multispecies, stochastic population dynamics with reproduction probabilities that depend nonlinearly…

Populations and Evolution · Quantitative Biology 2011-11-10 Per Arne Rikvold

The coexistence of multiple phytoplankton species despite their reliance on similar resources is often explained with mean-field models assuming mixed populations. In reality, observations of phytoplankton indicate spatial aggregation at…

Populations and Evolution · Quantitative Biology 2024-04-23 Coralie Picoche , William R. Young , Frédéric Barraquand

This paper investigates the coexistence of two competing species on random geometric graphs (RGGs) in continuous time. The species grow by occupying vacant sites according to Richardson's model, while simultaneously competing for occupied…

Probability · Mathematics 2025-01-28 Cristian F. Coletti , Lucas R. de Lima

A dynamic model for cell differentiation is studied, where cells with internal chemical reaction dynamics interact with each other and replicate. It leads to spontaneous differentiation of cells and determination, as is discussed in the…

adap-org · Physics 2007-05-23 Chikara Furusawa , Kunihiko Kaneko

It is known that the competitive exclusion principle holds for a large kind of models involving several species competing for a single resource in an homogeneous environment. Various works indicate that the coexistence is possible in an…

Analysis of PDEs · Mathematics 2014-07-22 François Castella , Sten Madec , Yvan Lagadeuc

Vine copulas, constructed using bivariate copulas as building blocks, provide a flexible framework for modeling multi-dimensional dependencies. However, this flexibility is accompanied by rapidly increasing complexity as dimensionality…

Methodology · Statistics 2025-04-25 Ichiro Nishi , Yoshinori Kawasaki

We investigate the problem of speciation and coexistence in simple ecosystems when the competition among individuals is included in the Eigen model for quasi-species. By suggesting an analogy between the competition among strains and the…

Statistical Mechanics · Physics 2008-02-03 Franco Bagnoli , Michele Bezzi

We introduce a simple physical picture to explain the process of molecular sorting, whereby specific proteins are concentrated and distilled into submicrometric lipid vesicles in eukaryotic cells. To this purpose, we formulate a model based…

Hypercycles are information integration systems which are thought to overcome the information crisis of prebiotic evolution by ensuring the coexistence of several short templates. For imperfect template replication, we derive a simple…

Populations and Evolution · Quantitative Biology 2008-06-13 Daniel A. M. M. Silvestre , Jose F. Fontanari

We consider a partial differential equation model for the growth of heterogeneous cell populations subdivided into multiple distinct discrete phenotypes. In this model, cells preferentially move towards regions where they feel less…

Analysis of PDEs · Mathematics 2025-04-04 José A. Carrillo , Tommaso Lorenzi , Fiona R. Macfarlane

Biomolecular condensates self-assemble when proteins and nucleic acids spontaneously demix to form droplets within the crowded intracellular milieu. This simple mechanism underlies the formation of a wide variety of membraneless…

Statistical Mechanics · Physics 2021-06-30 William M. Jacobs

As cells grow and divide under a given environment, they become crowded and resources are limited, as seen in bacterial biofilms and multicellular aggregates. These cells often show strong interactions through exchanging chemicals, as in…

Cell Behavior · Quantitative Biology 2017-02-08 Jumpei F Yamagishi , Nen Saito , Kunihiko Kaneko

During development, highly ordered structures emerge as cells collectively coordinate with each other. While recent advances have clarified how individual cells process and respond to external signals, understanding collective cellular…

Biological Physics · Physics 2026-02-05 Ashutosh Tripathi , Jörn Dunkel , Dominic J. Skinner

Biological and social systems are structured at multiple scales, and the incentives of individuals who interact in a group may diverge from the collective incentive of the group as a whole. Mechanisms to resolve this tension are responsible…

Populations and Evolution · Quantitative Biology 2023-05-31 Daniel B. Cooney , Simon A. Levin , Yoichiro Mori , Joshua B. Plotkin
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