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This paper presents a real-time simulation involving ''protozoan-like'' cells that evolve by natural selection in a physical 2D ecosystem. Selection pressure is exerted via the requirements to collect mass and energy from the surroundings…

Neural and Evolutionary Computing · Computer Science 2023-05-23 Dylan Cope

We propose a type-dependent branching model with mutation and competition for modeling phylogenies of a virus population. The competition kernel depends for any two virus particles on the particles' types, the total mass of the population…

Probability · Mathematics 2017-05-10 Sandra Kliem , Anita Winter

Understanding the spatial organisation of the genome in the cell nucleus is one of the current grand challenges in biophysics. Certain biochemical -- or epigenetic -- marks that are deposited along the genome are thought to play an…

Soft Condensed Matter · Physics 2020-01-08 Davide Michieletto , Davide Colí , Davide Marenduzzo , Enzo Orlandini

Individuals within any species exhibit differences in size, developmental state, or spatial location. These differences coupled with environmental fluctuations in demographic rates can have subtle effects on population persistence and…

Populations and Evolution · Quantitative Biology 2015-12-16 Gregory Roth , Sebastian J. Schreiber

In this paper, we discuss the conceptual underpinnings of Modern Coexistence Theory (MCT), a quantitative framework for understanding ecological coexistence. In order to use MCT to infer how species are coexisting, one must relate a complex…

Populations and Evolution · Quantitative Biology 2022-01-21 Evan Johnson , Alan Hastings

We study coexistence in discrete time multi-type frog models. We first show that for two types of particles on $\mathbb{Z}^d$, for $d\geq2$, for any jumping parameters $p_1, p_2 \in (0,1)$, coexistence occurs with positive probability for…

Probability · Mathematics 2024-02-23 Rishideep Roy , Kumarjit Saha

By generalizing a class of models recently introduced to account for protracted transients in biological systems, we identify a novel mechanism for hyperuniformity. In this model, competition of particles over a shared resource guides the…

Statistical Mechanics · Physics 2025-12-11 Tal Agranov , Natan Wiegenfeld , Omer Karin , Benjamin D. Simons

In multicellular organisms, several cell states coexist. For determining each cell type, cell-cell interactions are often essential, in addition to intracellular gene expression dynamics. Based on dynamical systems theory, we propose a…

Cell Behavior · Quantitative Biology 2007-12-05 Akihiko Nakajima , Kunihiko Kaneko

In this paper I describe a cellular automaton model of a multi-species ecosystem, suitable for the study of emergent properties of macroevolution. Unlike majority of ecological models, the number of coexisting species is not fixed. Starting…

Populations and Evolution · Quantitative Biology 2009-09-23 Wojciech Borkowski

We study time continuous branching processes with exponentially distributed lifetimes, with two types of cells that proliferate according to binary fission. A range of possible system dynamics are considered, each of which is characterized…

Probability · Mathematics 2022-04-27 Nam H Nguyen , Marek Kimmel

Protocells are supposed to have played a key role in the self-organizing processes leading to the emergence of life. Existing models either (i) describe protocell architecture and dynamics, given the existence of sets of collectively…

Molecular Networks · Quantitative Biology 2014-08-01 Roberto Serra , Alessandro Filisetti , Marco Villani , Alex Graudenzi , Chiara Damiani , Tommaso Panini

Chromosomal crossovers play a crucial role in meiotic cell division, as they ensure proper chromosome segregation and increase genetic variability. Experiments have consistently revealed two key observations across species: (i) the number…

Biological Physics · Physics 2025-09-12 Marcel Ernst , Riccardo Rossetto , David Zwicker

We discuss some stochastic spatial generalizations of the Lotka--Volterra model for competing species. The generalizations take the forms of spin systems on general discrete sets and interacting diffusions on integer lattices. Methods for…

Probability · Mathematics 2018-11-26 Yu-Ting Chen , Matthias Hammer

We consider a spatial stochastic model for a pathogen population growing inside a host that attempts to eliminate the pathogens through its immune system. The pathogen population is divided into different types. A pathogen can either…

Probability · Mathematics 2026-02-03 Fábio Lopes , Alejandro Roldán-Correa

In the present paper we study a lattice model of two species competing for the same resources. Monte Carlo simulations for d=1, 2, and 3 show that when resources are easily available both species coexist. However, when the supply of…

Populations and Evolution · Quantitative Biology 2011-03-09 Jacek Wendykier , Adam Lipowski , Antonio Luis Ferreira

Continuum models for the spatial dynamics of growing cell populations have been widely used to investigate the mechanisms underpinning tissue development and tumour invasion. These models consist of nonlinear partial differential equations…

Tissues and Organs · Quantitative Biology 2019-07-15 Mark AJ Chaplain , Tommaso Lorenzi , Fiona R Macfarlane

Stem cells are characterized by their ability to self-renew, as well as to differentiate and give rise to new populations of cells. Stem cell divisions are crucial for generative processes that occur during early development, and later in…

Applications · Statistics 2025-08-29 Haim Bar , Huyen Nguyen , Joanne Conover

Mechanisms leading to speciation are a major focus in evolutionary biology. In this paper, we present and study a stochastic model of population where individuals, with type a or A, are equivalent from ecological, demographical and spatial…

Populations and Evolution · Quantitative Biology 2017-04-20 Camille Coron , Manon Costa , Hélène Leman , Charline Smadi

Deterministic continuum models formulated in terms of non-local partial differential equations for the evolutionary dynamics of populations structured by phenotypic traits have been used recently to address open questions concerning the…

Populations and Evolution · Quantitative Biology 2020-10-14 Aleksandra Ardaševa , Robert A. Gatenby , Alexander R. A. Anderson , Helen M. Byrne , Philip K. Maini , Tommaso Lorenzi

Frequency-dependent selection reflects the interaction between different species as they battle for limited resources in their environment. In a stochastic evolutionary game the species relative fitnesses guides the evolutionary dynamics…

Probability · Mathematics 2020-12-29 Lea Popovic , Liam Peuckert