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Networks of neurons in the brain encode preferred patterns of neural activity via their synaptic connections. Despite receiving considerable attention, the precise relationship between network connectivity and encoded patterns is still…

Neurons and Cognition · Quantitative Biology 2015-02-25 Carina Curto , Anda Degeratu , Vladimir Itskov

Brains learn to represent information from a large set of stimuli, typically by weak supervision. Unsupervised learning is therefore a natural approach for exploring the design of biological neural networks and their computations.…

Neurons and Cognition · Quantitative Biology 2025-10-17 Roy Urbach , Elad Schneidman

Elements of neural networks, both biological and artificial, can be described by their selectivity for specific cognitive features. Understanding these features is important for understanding the inner workings of neural networks. For a…

Neural and Evolutionary Computing · Computer Science 2026-04-28 Nikita Pospelov , Andrei Chertkov , Maxim Beketov , Ivan Oseledets , Konstantin Anokhin

Over repeat presentations of the same stimulus, sensory neurons show variable responses. This "noise" is typically correlated between pairs of cells, and a question with rich history in neuroscience is how these noise correlations impact…

Neurons and Cognition · Quantitative Biology 2015-06-16 Yu Hu , Joel Zylberberg , Eric Shea-Brown

Learning is a complex dynamical process shaped by a range of interconnected decisions. Careful design of hyperparameter schedules for artificial neural networks or efficient allocation of cognitive resources by biological learners can…

Disordered Systems and Neural Networks · Physics 2025-07-11 Francesca Mignacco , Francesco Mori

With the Deep Neural Networks (DNNs) as a powerful function approximator, Deep Reinforcement Learning (DRL) has been excellently demonstrated on robotic control tasks. Compared to DNNs with vanilla artificial neurons, the biologically…

Artificial Intelligence · Computer Science 2022-09-23 Duzhen Zhang , Tielin Zhang , Shuncheng Jia , Xiang Cheng , Bo Xu

Sensory information propagates through successive processing stages in the brain, where synaptic weight patterns between stations determine how downstream neurons decode information from upstream populations. Although optimized synaptic…

Neurons and Cognition · Quantitative Biology 2026-02-26 Ori Hendler , Ronen Segev , Maoz Shamir

We present a theoretical application of an optimal experiment design (OED) methodology to the development of mathematical models to describe the stimulus-response relationship of sensory neurons. Although there are a few related studies in…

Neurons and Cognition · Quantitative Biology 2016-10-19 R. Ozgur Doruk , Kechen Zhang

A steadily increasing body of evidence suggests that the brain performs probabilistic inference to interpret and respond to sensory input and that trial-to-trial variability in neural activity plays an important role. The neural sampling…

Neurons and Cognition · Quantitative Biology 2017-07-07 Ilja Bytschok , Dominik Dold , Johannes Schemmel , Karlheinz Meier , Mihai A. Petrovici

We consider signal transaction in a simple neuronal model featuring intrinsic noise. The presence of noise limits the precision of neural responses and impacts the quality of neural signal transduction. We assess the signal transduction…

Biological Physics · Physics 2015-03-17 Michael J. Barber , Manfred L. Ristig

Despite intensive research, the mechanisms underlying how neurons encode external inputs remain poorly understood. Recent work has focused on the response of a single neuron to a weak, subthreshold periodic signal. By simulating the…

Neurons and Cognition · Quantitative Biology 2017-11-23 Maria Masoliver , Cristina Masoller

Neural circuits exhibit remarkable computational flexibility, enabling adaptive responses to noisy and ever-changing environmental cues. A fundamental question in neuroscience concerns how a wide range of behaviors can emerge from a…

Statistical Mechanics · Physics 2025-09-18 Giacomo Barzon , Daniel M. Busiello , Giorgio Nicoletti

Spike-based encoders represent information as sequences of spikes or pulses, which are transmitted between neurons. A prevailing consensus suggests that spike-based approaches demonstrate exceptional capabilities in capturing the temporal…

Signal Processing · Electrical Eng. & Systems 2025-06-03 MHD Anas Alsakkal , Runze Wang , Jayawan Wijekoon , Huajin Tang

The coding properties of cells with different types of receptive fields have been studied for decades. ON-type neurons fire in response to positive fluctuations of the time-dependent stimulus, whereas OFF cells are driven by negative…

Neurons and Cognition · Quantitative Biology 2009-09-10 Eugenio Urdapilleta , Ines Samengo

Why do neurons communicate through spikes? By definition, spikes are all-or-none neural events which occur at continuous times. In other words, spikes are on one side binary, existing or not without further details, and on the other can…

Neurons and Cognition · Quantitative Biology 2024-04-12 Antoine Grimaldi , Amélie Gruel , Camille Besnainou , Jean-Nicolas Jérémie , Jean Martinet , Laurent U Perrinet

A single neuron is known to generate almost identical spike trains when the same fluctuating input is repeatedly applied. Here, we study the reliability of spike firing in a pulse-coupled network of oscillator neurons receiving fluctuating…

Adaptation and Self-Organizing Systems · Physics 2015-05-13 Jun-nosuke Teramae , Tomoki Fukai

We present a theoretical study aiming at model fitting for sensory neurons. Conventional neural network training approaches are not applicable to this problem due to lack of continuous data. Although the stimulus can be considered as a…

Neurons and Cognition · Quantitative Biology 2017-09-28 R. Ozgur Doruk , Kechen Zhang

Following a stimulus, the neural response typically strongly varies in time and across neurons before settling to a steady-state. While classical population coding theory disregards the temporal dimension, recent works have argued that…

Neurons and Cognition · Quantitative Biology 2019-07-05 Giulio Bondanelli , Srdjan Ostojic

Spiking neural networks (SNNs) are distributed trainable systems whose computing elements, or neurons, are characterized by internal analog dynamics and by digital and sparse synaptic communications. The sparsity of the synaptic spiking…

Machine Learning · Computer Science 2020-01-08 Hyeryung Jang , Osvaldo Simeone , Brian Gardner , André Grüning

In spiking neural networks, the information is conveyed by the spike times, that depend on the intrinsic dynamics of each neuron, the input they receive and on the connections between neurons. In this article we study the Markovian nature…

Applications · Statistics 2012-11-07 Jonathan Touboul , Olivier Faugeras
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