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DNA autoionization is a fundamental process wherein UV-photoexcited nucleobases dissipate energy by charge transfer to the environment without undergoing chemical damage. Here, single-wall carbon nanotubes (SWNT) are explored as a…

Mesoscale and Nanoscale Physics · Physics 2021-07-02 Tetyana Ignatova , Alexander Balaeff , Ming Zheng , Michael Blades , Peter Stoeckl , Slava V. Rotkin

Silicon nanochannel biological field effect transistors have been developed for glucose detection. The device is nanofabricated from a silicon-on-insulator wafer with a top-down approach and surface functionalized with glucose oxidase. The…

Biological Physics · Physics 2008-02-14 Xihua Wang , Yu Chen , Katherine A. Gibney , Shyamsunder Erramilli , Pritiraj Mohanty

Engineered electromagnetic fields in plasmonic nanopores enable enhanced optical detection and their use in single molecule sequencing. Here, a plasmonic nanopore prepared in a thick nanoporous film is used to investigate the interaction…

Nucleic acid sensing is crucial for advancing diagnostics, therapeutic monitoring and molecu-lar biology research, by enabling the precise identification of DNA and RNA interactions. Here, we present an innovative sensing platform based on…

The article demonstrates a technique for fabricating a structure with the inclusion of suspended DNA threads and manipulating them using composite nanotweezers with shape memory effect. This technique could be suitable for stretching of…

Metallic nanohole arrays have shown their potential as sensing tools. Important research supported by sophisticated laboratory experiments have been recently carried out, that may help to develop practical devices to be implemented in the…

Applied Physics · Physics 2019-05-01 A. Franco , D. Otaduy , A. I. Barreda , J. L. FernÁndez-Luna , S. Merino , F. GonzÁlez , F. Moreno

The measured electric resistance of carbon nanotubes wrapped with DNA molecules depends strongly on the spin of the injected electrons. Motivated by these experiments, we study the effect of helix-shaped potentials on the electronic…

Mesoscale and Nanoscale Physics · Physics 2018-11-14 Yotam Perlitz , Karen Michaeli

Electrochemical Biosensors are uniquely positioned to offer real-time in vivo molecular sensing due to their robustness to both biofluids and contaminants found in biofluids, and their adaptability for the detection of different analytes by…

Biological Physics · Physics 2024-10-04 Philip S Lukeman

Quantum sensing techniques have been successful in pushing the sensitivity limits in numerous fields, and hold great promise for scanning probes that study nano-scale devices and novel materials. However, forming a nano-scale qubit that is…

Mesoscale and Nanoscale Physics · Physics 2019-08-23 Ilya Khivrich , Shahal Ilani

Charge transfer can take place along double helical DNA over distances as long as 30 nanometers. However, given the active role of the thermal environment surrounding charge carriers in DNA, physical mechanisms driving the transfer process…

Mesoscale and Nanoscale Physics · Physics 2020-12-04 Roman Korol , Dvira Segal

Motivated by recent experiments we have studied the optical conductivity of DNA in its natural environment containing water molecules and counter ions. Our density functional theory calculations (using SIESTA) for four base pair B-DNA with…

Soft Condensed Matter · Physics 2009-11-11 A. Huebsch , R. G. Endres , D. L. Cox , R. R. P. Singh

In this study, we examine the mechanism of nanopore-based DNA sequencing using a voltage bias across a graphene nanoribbon. Using density functional theory and a non-equilibrium Green's function approach, we determine the transmission…

Mesoscale and Nanoscale Physics · Physics 2018-09-11 Hannah L. McFarland , Towfiq Ahmed , Jian-Xin Zhu , Alexander V. Balatsky , Jason T. Haraldsen

Measuring the electrophoretic mobility of molecules is a powerful experimental approach for investigating biomolecular processes. A frequent challenge in the context of single-particle measurements is throughput, limiting the obtainable…

Optics · Physics 2021-07-26 Xuanhui Meng , Philipp Kukura , Sanli Faez

The energetic and transport properties of a double-stranded DNA dodecamer encapsulated in hydrophobic carbon nanotubes are probed employing two limiting nanotube diameters, D=4 nm and D=3 nm, corresponding to (51,0) and (40,0) zig-zag…

Biological Physics · Physics 2016-05-06 Fernando J. A. L. Cruz , Juan J. de Pablo , José P. B. Mota

In this review article, we focus on emerging nanocantilever based biological sensors and discuss the response of nanocantilevers towards bio-molecules capture. The article guides the reader through various modes of operation (e.g., static…

Instrumentation and Detectors · Physics 2013-05-30 Ankit Jain , Muhammad Ashraful Alam

In the last decade, solid state nanopores nanogaps have attracted significant interest in the rapid detection of DNA nucleotides. However, reducing the noise through the controlled translocating of the DNA nucleobases is a central issue for…

Applied Physics · Physics 2020-03-18 Rameshwar L. Kumawat , Biswarup Pathak

The use of optics in microelectronic circuits to overcome the limitation of metallic interconnects is more and more considered as a viable solution. Among future silicon compatible materials, carbon nanotubes are promising candidates thanks…

The optical absorption spectrum of the carbon (4,2) nanotube is computed using an ab-initio many-body approach which takes into account excitonic effects. We develop a new method involving a local basis set which is symmetric with respect…

Materials Science · Physics 2009-11-10 Eric Chang , Giovanni Bussi , Alice Ruini , Elisa Molinari

Dielectric screening plays a vital role for the physical properties in the nanoscale and also alters our ability to detect and characterize nanomaterials by optical techniques. We study the dielectric screening inside of carbon nanotubes…

Mesoscale and Nanoscale Physics · Physics 2024-04-02 Georgy Gordeev , Sören Wasserroth , Han Li , Ado Jorio , Benjamin S. Flavel , Stephanie Reich

We developed a novel detection method for osteopontin (OPN), a new biomarker for prostate cancer, by attaching a genetically engineered single chain variable fragment (scFv) protein with high binding affinity for OPN to a carbon nanotube…

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