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One of the key characteristics of multicellular organisms is the ability to establish and maintain shapes, or morphologies, under a variety of physical and chemical perturbations. A quantitative description of the underlying morphological…

Tissues and Organs · Quantitative Biology 2019-05-22 Anne-Mieke Reijne , Gunnar Pruessner , Giovanni Sena

Experimental data regarding auxin and venation formation exist at both macroscopic and molecular scales, and we attempt to unify them into a comprehensive model for venation formation. We begin with a set of principles to guide an abstract…

Quantitative Methods · Quantitative Biology 2009-05-28 Pavel Dimitrov , Steven W. Zucker

We present a simple three-dimensional model to describe the autonomous expansion of a substrate which grows driven by the local mean curvature of its surface. The model aims to reproduce the nest construction process in arboreal…

Adaptation and Self-Organizing Systems · Physics 2020-02-11 Giulio Facchini , Alexandre Lazarescu , Andrea Perna , Stéphan Douady

We introduce a general, efficient method to completely describe the topology of individual grains, bubbles, and cells in three-dimensional polycrystals, foams, and other multicellular microstructures. This approach is applied to a pair of…

Materials Science · Physics 2017-11-10 Emanuel A. Lazar , Jeremy K. Mason , Robert D. MacPherson , David J. Srolovitz

We investigate morphologies of proliferating cellular tissue using a newly developed numerical simulation model for mechanical cell division. The model reproduces structures of simple multi-cellular organisms via simple rules for selective…

Soft Condensed Matter · Physics 2018-11-20 Pranav Madhikar , Jan Åström , Björn Baumeier , Mikko Karttunen

How morphogenesis depends on cell properties is an active direction of research. Here, we focus on mechanical models of growing plant tissues, where microscopic (sub)cellular structure is taken into account. In order to establish links…

Analysis of PDEs · Mathematics 2023-11-21 Arezki Boudaoud , Annamaria Kiss , Mariya Ptashnyk

Organoids are complex, three dimensional, self-organizing cell cultures which manifest organ-like features and represent a powerful platform for studying human disease and developing treatment options. Organoid development is characterized…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Chase Cartwright , Gongbo Guo , Sai Teja Pusuluri , Christopher N. Mayhew , Mark Hester , Horacio E. Castillo

The Eden cell growth model is a simple discrete stochastic process which produces a "blob" in $\mathbb{R}^d$: start with one cube in the regular grid, and at each time step add a neighboring cube uniformly at random. This process has been…

Probability · Mathematics 2020-12-15 Fedor Manin , Erika Roldan , Benjamin Schweinhart

Cell colonies of bacteria, tumour cells and fungi, under nutrient limited growth conditions, exhibit complex branched growth patterns. In order to investigate this phenomenon we present a simple hybrid cellular automaton model of cell…

Biological Physics · Physics 2007-05-23 P. Gerlee , A. R. A Anderson

Samaras, a distinct category of fruit, are composed of heavier seeds and lighter wings. Diversity in morphologies and structures subtly contributes to the flight patterns of various seeds, thereby serving as a key factor in the reproductive…

Fluid Dynamics · Physics 2024-11-15 Zhao-Bang Hou , Jun-Duo Zhang , Yun-Da Li , Yong-Xia Jia , Wei-Xi Huang

Existing mathematical models of the shoot apical meristem (SAM) explain nucleation and confinement of a stem cell domain by Turing's mechanism, assuming that the diffusion coefficients of the activator (WUSCHEL) and inhibitor (CLAVATA) are…

Molecular Networks · Quantitative Biology 2017-12-08 Dorjsuren Battogtokh , John J. Tyson

The adoption of agroecological practices will be crucial to address the challenges of climate change and biodiversity loss. Such practices favor the cultivation of plants in complex mixtures with layouts differing from the monoculture…

Populations and Evolution · Quantitative Biology 2024-09-26 Julian Talbot , Pascal Viot , David Colliaux

A random planar quadrangulation process is introduced as an approximation for certain cellular automata in terms of random growth of rays from a given set of points. This model turns out to be a particular (rectangular) case of the…

Probability · Mathematics 2025-10-17 Emily Ewers , Tatyana Turova

Natural slender structures, such as plant leaves, petals, and tendrils, often exhibit complex three-dimensional (3D) morphologies-including twisting, helical coiling, and saddle-bending-driven by differential growth. The resulting internal…

Soft Condensed Matter · Physics 2025-06-24 Hao Liu , Mingwu Li , Dabiao Liu

As an injury heals, an embryo develops, or a carcinoma spreads, epithelial cells systematically change their shape. In each of these processes cell shape is studied extensively, whereas variation of shape from cell-to-cell is dismissed most…

In this work, a new model for macroscopic plant tissue growth based on dynamical Riemannian geometry is presented. We treat 1D and 2D tissues as continuous, deformable, growing geometries for sizes larger than 1mm. The dynamics of the…

Tissues and Organs · Quantitative Biology 2016-02-05 Julia Pulwicki

The principles underlying plant development are extended to allow a more molecular mechanism to elaborate the schema by which ground cells differentiate into vascular cells. Biophysical considerations dictate that linear dynamics are not…

Quantitative Methods · Quantitative Biology 2009-05-29 Pavel Dimitrov , Steven W. Zucker

We propose here to interpret and model peculiar plant morphologies (cushions, tussocks) observed in the Andean altiplano as localized structures. Such structures resulting in a patchy, aperiodic aspect of the vegetation cover are…

Pattern Formation and Solitons · Physics 2015-06-22 P. Couteron , F. Anthelme , M. Clerc , D. Escaff , C. Fernandez-Oto , M. Tlidi

Recent advances in microscopy techniques make it possible to study the growth, dynamics, and response of complex biophysical systems at single-cell resolution, from bacterial communities to tissues and organoids. In contrast to ordered…

Soft Condensed Matter · Physics 2021-01-29 Dominic J. Skinner , Boya Song , Hannah Jeckel , Eric Jelli , Knut Drescher , Jörn Dunkel

Understanding how growth induces form is a longstanding biological question. Many studies concentrated on the shapes of plant cells, fungi or bacteria. Some others have shown the importance of the mechanical properties of bacterial walls…

Biological Physics · Physics 2007-05-23 Arezki Boudaoud