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Related papers: Turing patterns from dynamics of early HIV infecti…

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In this paper, we investigate a novel 3-compartment model of HIV infection of CD4$^+$ T-cells with a mass action term by including two versions: one baseline ODE model and one delay-differential equation (DDE) model with a constant discrete…

Populations and Evolution · Quantitative Biology 2021-01-05 Hoang Anh Ngo , Hung Dang Nguyen , Mehmet Dik

A dynamic model of non-lineal time-dependent ordinary differential equations (ODE) has been applied to the interactions of a HIV infection with the immune system cells. This model has been simplified into two compartments: lymph node and…

Cell Behavior · Quantitative Biology 2020-08-07 Miguel Ramos Pascual

Multiple mechanisms in the HIV lifecycle play a role in its ability to evade therapy and become a chronic, difficult-to-treat infection. Within its major cellular target, the activated T cell, many steps occur between viral entry and viral…

Cell Behavior · Quantitative Biology 2017-12-04 Jayodita C. Sanghvi , Don Mai , Adam P. Arkin , David V. Schaffer

Broadly neutralizing antibodies are promising candidates for treatment and prevention of HIV-1 infections. Such antibodies can temporarily suppress viral load in infected individuals; however, the virus often rebounds by escape mutants that…

Populations and Evolution · Quantitative Biology 2022-10-12 Matthijs Meijers , Kanika Vanshylla , Henning Gruell , Florian Klein , Michael Laessig

An increasing amount of geo-referenced mobile phone data enables the identification of behavioral patterns, habits and movements of people. With this data, we can extract the knowledge potentially useful for many applications including the…

Applications · Statistics 2015-03-24 Sanja Brdar , Katarina Gavric , Dubravko Culibrk , Vladimir Crnojevic

Chronic infection with hepatitis B virus (HBV) can lead to formation of abnormal nodular structures within the liver. To address how changes in liver anatomy affect overall virus-host dynamics, we developed within-host ordinary differential…

Other Quantitative Biology · Quantitative Biology 2025-08-01 Keoni Castellano , Omar Saucedo , Stanca M. Ciupe

Motivated by bacterial chemotaxis and multi-species ecological interactions in heterogeneous environments, we study a general one-dimensional reaction-cross-diffusion system in the presence of spatial heterogeneity in both transport and…

Pattern Formation and Solitons · Physics 2023-03-08 Eamonn A. Gaffney , Andrew L. Krause , Philip K. Maini , Chenyuan Wang

Reaction-diffusion processes across layered media arise in several scientific domains such as pattern-forming E. coli on agar substrates, epidermal-mesenchymal coupling in development, and symmetry-breaking in cell polarisation. We develop…

Pattern Formation and Solitons · Physics 2020-09-18 Andrew L. Krause , Václav Klika , Jacob Halatek , Paul K. Grant , Thomas E. Woolley , Neil Dalchau , Eamonn A. Gaffney

We propose a time-parameterized analogy between the thermodynamic behavior of a 3-level energy system and the progression of the HIV infection described by the cell population evolution generated by an appropriated cellular automata model.…

Populations and Evolution · Quantitative Biology 2020-06-24 Ramón E. R. González , P. H. Figueirêdo , S. Coutinho

Mathematical modeling and analysis can provide insight on the dynamics of ecosystems which maintain biodiversity in the face of competitive and prey-predator interactions. Of primary interests are the underlying structure and features which…

Populations and Evolution · Quantitative Biology 2017-01-03 Cameron J. Browne

Turing instabilities for a two species reaction-diffusion systems is studied under anisotropic diffusion. More specifically, the diffusion constants which characterize the ability of the species to relocate in space are direction sensitive.…

Statistical Mechanics · Physics 2015-09-30 Daniel M. Busiello , Gwendoline Planchon , Malbor Asllani , Timoteo Carletti , Duccio Fanelli

We establish a stochastic HIV/AIDS model for the individuals with protection awareness and reveal how the protection awareness plays its important role in the control of AIDS. We firstly show that there exists a global positive solution for…

Dynamical Systems · Mathematics 2023-03-01 Xuanpei Zhai , Wenshuang Li , Fengying Wei , Xuerong Mao

The control of opportunistic infections among HIV infected individuals should be one of the major public health concerns in reducing mortality rate of individuals living with HIV/AIDS. In this study a deterministic co-infection mathematical…

Dynamical Systems · Mathematics 2024-08-02 Michael Byamukama , Damian Kajunguri , Martin Karuhanga

Oxidative stress, a reaction caused by the imbalance between the reactive oxygen species of human organism and its ability to detoxify reactive intermediates and to repair the resulting damage plays an important role in HIV-infections. On…

Populations and Evolution · Quantitative Biology 2018-08-08 Shaoli Wang , Fei Xu , Xinyu Song

We study the global stability of a class of models for in-vivo virus dynamics, that take into account the CTL immune response and display antigenic variation. This class includes a number of models that have been extensively used to model…

Populations and Evolution · Quantitative Biology 2013-01-21 Max O. Souza , Jorge P. Zubelli

Viral deep-sequencing data play a crucial role toward understanding disease transmission network flows, because the higher resolution of these data compared to standard Sanger sequencing provide evidence into the direction of infectious…

Methodology · Statistics 2023-02-23 Fan Bu , Joseph Kagaayi , Kate Grabowski , Oliver Ratmann , Jason Xu

We investigate the celebrated mathematical SICA model but using fractional differential equations in order to better describe the dynamics of HIV-AIDS infection. The infection process is modelled by a general functional response and the…

Optimization and Control · Mathematics 2021-01-21 Adnane Boukhouima , El Mehdi Lotfi , Marouane Mahrouf , Silverio Rosa , Delfim F. M. Torres , Noura Yousfi

The study of pattern-forming instabilities in reaction-diffusion systems on growing or otherwise time-dependent domains arises in a variety of settings, including applications in developmental biology, spatial ecology, and experimental…

Pattern Formation and Solitons · Physics 2022-07-11 Robert A. Van Gorder , Václav Klika , Andrew L. Krause

Epidemic spreading of infectious diseases is ubiquitous and has often considerable impact on public health and economic wealth. The large variability in spatio-temporal patterns of epidemics prohibits simple interventions and demands for a…

Populations and Evolution · Quantitative Biology 2010-11-25 Christel Kamp

In this paper, we propose a mathematical model for HIV-1 infection with intracellular delay. The model examines a viral-therapy for controlling infections through recombining HIV-1 virus with a genetically modified virus. For this model,…

Dynamical Systems · Mathematics 2014-04-10 Yun Tian , Yu Bai , Pei Yu