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The simulation of blood flow and pressure in arteries requires outflow boundary conditions that incorporate models of downstream domains. We previously described a coupled multidomain method to couple analytical models of the downstream…

Medical Physics · Physics 2020-07-17 Irene Vignon-Clementel , C. A. Figueroa , K. E. Jansen , C. A. Taylor

Ischemia leading to heart attacks and strokes is the major cause of deaths in the world. Whether an occlusion occurs or not, depends on the ability of a growing thrombus to resist forces exerted on its structure. This manuscript provides…

Cell Behavior · Quantitative Biology 2019-01-16 Olufemi Emmanuel Kadri , Vishnu Deep Chandran , Migle Surblyte , Roman S. Voronov

It is investigated a possibility of physical interpretation of vector fields (dynamic flows) in Euclidean spaces of higher dimension. There are analyzed the methods of measurements of dynamic flows, the characteristics of dynamic flow and…

General Mathematics · Mathematics 2007-05-23 I. V. Bayak

Vortical blood flow in the human left ventricular (LV) inflow initiates from the mitral valve (MV) and evolves within the LV during diastolic E-filling. Hence, vortical flow links MV and LV hemodynamics. This study sought to elucidate and…

This paper reports on the derivation and implementation of a shape optimization procedure for the minimization of hemolysis induction in biomedical devices. Hemolysis is a blood damaging phenomenon that may occur in mechanical…

Fluid Dynamics · Physics 2021-01-27 Georgios Bletsos , Niklas Kühl , Thomas Rung

Multi-modality cardiac imaging plays a key role in the management of patients with cardiovascular diseases. It allows a combination of complementary anatomical, morphological and functional information, increases diagnosis accuracy, and…

Image and Video Processing · Electrical Eng. & Systems 2022-08-30 Lei Li , Wangbin Ding , Liqun Huang , Xiahai Zhuang , Vicente Grau

In fluid dynamics, one of the most important research fields is hydrodynamic instabilities and their evolution in different flow regimes. The investigation of said instabilities is concerned with the highly non-linear dynamics. Currently,…

Fluid Dynamics · Physics 2020-04-28 Re'em Harel , Matan Rusanovsky , Yehonatan Fridman , Assaf Shimony , Gal Oren

We investigate the rheological characteristics of human blood plasma in shear and elongational flows. While we can confirm a Newtonian behavior in shear flow within experimental resolution, we find a viscoelastic behavior of blood plasma in…

Biological Physics · Physics 2013-02-19 M. Brust , C. Schaefer , L. Pan , M. Garcia , P. E. Arratia , C Wagner

Widefield calcium imaging has recently emerged as a powerful experimental technique to record coordinated large-scale brain activity. These measurements present a unique opportunity to characterize spatiotemporal coherent structures that…

Neurons and Cognition · Quantitative Biology 2021-09-07 Nathaniel J Linden , Dennis R Tabuena , Nicholas A Steinmetz , William J Moody , Steven L Brunton , Bingni W Brunton

In this paper, we introduce an adapted one-dimensional (1D) reduced model aimed at analyzing blood flow within stenosed arteries. Differing from the prevailing 1D model \cite{Formaggia2003, Sherwin2003_2, Sherwin2003, Quarteroni2004,…

Numerical Analysis · Mathematics 2024-09-25 Suncica Canic , Shihan Guo , Yifan Wang , Xiaohe Yue , Haibiao Zheng

Blood vessel constriction is simulated with particle-based method using a molecular dynamics authoring software known as Molecular Workbench (WM). Blood flow and vessel wall, the only components considered in constructing a blood vessel,…

Biological Physics · Physics 2014-04-01 Mohamad Rendi , Suprijadi , Sparisoma Viridi

We illustrate the potential of PDE-based traffic flow control in cardiovascular flow analysis, monitoring, and control, presenting a PDE-based control-oriented formulation, for 1-D blood flow dynamics in the presence of stenosis. This is…

Optimization and Control · Mathematics 2021-12-23 Nikolaos Bekiaris-Liberis

For simulation models of pedestrian dynamics there are always the issues of calibration and validation. These are usually done by comparing measured properties of the dynamics found in observation, experiments and simulation in certain…

Physics and Society · Physics 2014-02-10 Tobias Kretz

Red blood cells (RBCs) are an essential component of blood. A method to include the particulate nature of blood is introduced here with the goal of studying circulation in large-scale realistic vessels. The method uses a combination of the…

Medical Physics · Physics 2011-07-26 Simone Melchionna

We propose an ultrasound approach which provides, with one single examination and one single device, access to three bone biomarkers: anatomy, tissue quality and blood flow. It unlocks ultrasound imaging inside bone by accounting for…

Recent studies on viscous streaming flows in two dimensions have elucidated the impact of body curvature variations on resulting flow topology and dynamics, with opportunities for microfluidic applications. Following that, we present here a…

Fluid Dynamics · Physics 2023-06-22 Fan Kiat Chan , Yashraj Bhosale , Tejaswin Parthasarathy , Mattia Gazzola

Prediction of the blood flow characteristics is of utmost importance for understanding the behavior of the blood arterial network, especially in the presence of vascular diseases such as stenosis. Computational fluid dynamics (CFD) has…

Machine Learning · Computer Science 2021-11-11 Mohammad Farajtabar , Mohit Biglarian , Morteza Miansari

The clinical application of patient-specific modelling of the heart can provide valuable insights in supplementing and advancing methods of diagnosis as well as helping to devise the best possible therapeutic approach for each individual…

Medical Physics · Physics 2023-08-03 Sebastian Skatulla , Carlo Sansour , Mary Familusi , Jagir Hussan , Ntobeko Ntusi

Although atrial fibrillation (AF), a common arrhythmia, frequently presents in patients with underlying valvular disease, its hemodynamic contributions are not fully understood. The present work aimed to computationally study how physical…

Despite decades of research on blood flow, an analogue of Navier-Stokes equations that accurately describe blood flow properties has not been established yet. The reason behind this is that the properties of blood flow seem \`a priori non…