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Modern analytical pipelines routinely deploy multiple deep learning and retrieval models that rely on approximate nearest-neighbor (ANN) indexes to support efficient similarity-based search. While many state-of-the-art ANN-indexes are…

Information Retrieval · Computer Science 2025-07-30 Omar Shahbaz Khan , Gylfi Þór Guðmundsson , Björn Þór Jónsson

We present BackboneLearn: an open-source software package and framework for scaling mixed-integer optimization (MIO) problems with indicator variables to high-dimensional problems. This optimization paradigm can naturally be used to…

Machine Learning · Computer Science 2023-11-27 Vassilis Digalakis , Christos Ziakas

We introduce HONEY; a new specialized programming language designed to facilitate the processing of multivariate, asynchronous and non-uniformly sampled symbolic and scalar time sequences. When compiled, a Honey program is transformed into…

Programming Languages · Computer Science 2016-09-13 Mathieu Guillame-Bert

Energy landscapes provide a valuable means for studying the folding dynamics of short RNA molecules in detail by modeling all possible structures and their transitions. Higher abstraction levels based on a macro-state decomposition of the…

Biomolecules · Quantitative Biology 2014-09-09 Martin Mann , Marcel Kucharik , Christoph Flamm , Michael T. Wolfinger

Multimodal LLMs are turning their focus to video benchmarks, however most video benchmarks only provide outcome supervision, with no intermediate or interpretable reasoning steps. This makes it challenging to assess if models are truly able…

The emergence of High-Level Synthesis (HLS) tools shifted the paradigm of hardware design by making the process of mapping high-level programming languages to hardware design such as C to VHDL/Verilog feasible. HLS tools offer a plethora of…

Bayesian structural equation modelling (BSEM) offers many advantages such as principled uncertainty quantification, small-sample regularisation, and flexible model specification. However, the Markov chain Monte Carlo (MCMC) methods on which…

Computation · Statistics 2026-05-20 Haziq Jamil , Håvard Rue

Memory-safety violations in C and C++ programs continue to enable sophisticated exploitation techniques such as control-flow hijacking and data-oriented attacks. Existing hardware defenses either rely on address space layout randomization…

Multi-GPU programming traditionally requires developers to navigate complex trade-offs between performance and programmability. High-performance implementations typically rely on low-level HIP/CUDA communication libraries that demand…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-11-18 Muhammad Awad , Muhammad Osama , Brandon Potter

Linked lists have long served as a valuable teaching tool in programming. However, the question arises: Are they truly practical for everyday program use? In most cases, it appears that array-based data structures offer distinct advantages,…

Data Structures and Algorithms · Computer Science 2024-08-29 Benoît Sonntag , Dominique Colnet

This project enables RISC-V microkernel support in IREE, an MLIR-based machine learning compiler and runtime. The approach begins by enabling the lowering of MLIR linalg dialect contraction ops to linalg.mmt4d op for the RISC-V64 target…

Hardware Architecture · Computer Science 2025-08-22 Adeel Ahmad , Ahmad Tameem Kamal , Nouman Amir , Bilal Zafar , Saad Bin Nasir

Several manufacturers have already started to commercialize near-bank Processing-In-Memory (PIM) architectures. Near-bank PIM architectures place simple cores close to DRAM banks and can yield significant performance and energy improvements…

Hardware Architecture · Computer Science 2022-05-24 Christina Giannoula , Ivan Fernandez , Juan Gómez-Luna , Nectarios Koziris , Georgios Goumas , Onur Mutlu

RNA 3D architectures are stabilized by sophisticated networks of (non-canonical) base pair interactions, which can be conveniently encoded as multi-relational graphs and efficiently exploited by graph theoretical approaches and recent…

Quantitative Methods · Quantitative Biology 2022-06-03 Vincent Mallet , Carlos Oliver , Jonathan Broadbent , William L. Hamilton , Jérôme Waldispühl

In the dynamic field of materials science, the quest to find optimal structures with low potential energy is of great significance. Over the past two decades, the minima hopping algorithm has emerged as a successful tool in this pursuit. We…

Processing-in-cache (PiC) and Processing-in-memory (PiM) architectures, especially those utilizing bit-line computing, offer promising solutions to mitigate data movement bottlenecks within the memory hierarchy. While previous studies have…

Computers and Society · Computer Science 2024-07-30 Dhruv Gajaria , Tosiron Adegbija , Kevin Gomez

Deploying deep neural networks (DNNs) on resource-constrained IoT devices remains a challenging problem, often requiring hardware modifications tailored to individual AI models. Existing accelerator-generation tools, such as AMD's FINN, do…

There are numerous examples of problems in symbolic algebra in which the required storage grows far beyond the limitations even of the distributed RAM of a cluster. Often this limitation determines how large a problem one can solve in…

Distributed, Parallel, and Cluster Computing · Computer Science 2010-06-11 Daniel Kunkle

DNA sequence classification is a fundamental task in computational biology with vast implications for applications such as disease prevention and drug design. Therefore, fast high-quality sequence classifiers are significantly important.…

Machine Learning · Computer Science 2023-11-07 Marcel Khalifa , Barak Hoffer , Orian Leitersdorf , Robert Hanhan , Ben Perach , Leonid Yavits , Shahar Kvatinsky

ABCpy is a highly modular scientific library for Approximate Bayesian Computation (ABC) written in Python. The main contribution of this paper is to document a software engineering effort that enables domain scientists to easily apply ABC…

Efficiently optimizing multi-model inference pipelines for fast, accurate, and cost-effective inference is a crucial challenge in machine learning production systems, given their tight end-to-end latency requirements. To simplify the…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-05-28 Saeid Ghafouri , Kamran Razavi , Mehran Salmani , Alireza Sanaee , Tania Lorido-Botran , Lin Wang , Joseph Doyle , Pooyan Jamshidi
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