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Target speaker extraction (TSE) aims to extract the speech of a target speaker from mixtures containing multiple competing speakers. Conventional TSE systems predominantly rely on speaker cues, such as pre-enrolled speech, to identify and…

Audio and Speech Processing · Electrical Eng. & Systems 2026-02-10 Haoyu Li , Yu Xi , Yidi Jiang , Shuai Wang , Kate Knill , Mark Gales , Haizhou Li , Kai Yu

Most deep noise suppression (DNS) models are trained with reference-based losses requiring access to clean speech. However, sometimes an additive microphone model is insufficient for real-world applications. Accordingly, ways to use real…

Audio and Speech Processing · Electrical Eng. & Systems 2023-09-06 Ziyi Xu , Marvin Sach , Jan Pirklbauer , Tim Fingscheidt

Approximate Computing (AxC) techniques trade off the computation accuracy for performance, energy, and area reduction gains. The trade-off is particularly convenient when the applications are intrinsically tolerant to some accuracy loss, as…

Neural and Evolutionary Computing · Computer Science 2024-12-23 Sepide Saeedi , Alessio Carpegna , Alessandro Savino , Stefano Di Carlo

Single-cell RNA sequencing (scRNA-seq) enables transcriptomic profiling at cellular resolution but suffers from pervasive dropout events that obscure biological signals. We present SCR-MF, a modular two-stage workflow that combines…

Machine Learning · Computer Science 2025-11-24 Ali Anaissi , Deshao Liu , Yuanzhe Jia , Weidong Huang , Widad Alyassine , Junaid Akram

Spatial transcriptomics (ST) is an emerging technology that enables researchers to investigate the molecular relationships underlying tissue morphology. However, acquiring ST data remains prohibitively expensive, and traditional fixed-grid…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Junchao Zhu , Ruining Deng , Junlin Guo , Tianyuan Yao , Chongyu Qu , Juming Xiong , Siqi Lu , Zhengyi Lu , Yanfan Zhu , Marilyn Lionts , Yuechen Yang , Yalin Zheng , Yu Wang , Shilin Zhao , Haichun Yang , Yuankai Huo

Scientific archives now contain hundreds of petabytes of data across genomics, ecology, climate, and molecular biology that could reveal undiscovered patterns if systematically analyzed at scale. Large-scale, weakly-supervised datasets in…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Samuel Stevens , Jacob Beattie , Tanya Berger-Wolf , Yu Su

Traditional language models, adept at next-token prediction in text sequences, often struggle with transduction tasks between distinct symbolic systems, particularly when parallel data is scarce. Addressing this issue, we introduce…

Machine Learning · Computer Science 2024-02-19 Mohammad Hossein Amani , Nicolas Mario Baldwin , Amin Mansouri , Martin Josifoski , Maxime Peyrard , Robert West

Efficient video recognition is a hot-spot research topic with the explosive growth of multimedia data on the Internet and mobile devices. Most existing methods select the salient frames without awareness of the class-specific saliency…

Computer Vision and Pattern Recognition · Computer Science 2022-07-22 Boyang Xia , Zhihao Wang , Wenhao Wu , Haoran Wang , Jungong Han

Genome annotation is an important issue in biology which has long been addressed with gene prediction methods and manual experiments requiring biological expertise. The expanding Next Generation Sequencing technologies and their enhanced…

Computation · Statistics 2013-07-02 Alice Cleynen , Michel Koskas , Emilie Lebarbier , Guillem Rigaill , Stephane Robin

Cell shape analysis is important in biomedical research. Deep learning methods may perform to segment individual cells if they use sufficient training data that the boundary of each cell is annotated. However, it is very time-consuming for…

Image and Video Processing · Electrical Eng. & Systems 2020-02-26 Kazuya Nishimura , Dai Fei Elmer Ker , Ryoma Bise

Understanding cellular responses to stimuli is crucial for biological discovery and drug development. Transcriptomics provides interpretable, gene-level insights, while microscopy imaging offers rich predictive features but is harder to…

Background: Spatial transcriptomics have emerged as a powerful tool in biomedical research because of its ability to capture both the spatial contexts and abundance of the complete RNA transcript profile in organs of interest. However,…

Genomics · Quantitative Biology 2025-04-18 Shuo Shuo Liu , Shikun Wang , Yuxuan Chen , Anil K. Rustgi , Ming Yuan , Jianhua Hu

Spatial Transcriptomics is a groundbreaking technology that integrates histology images with spatially resolved gene expression profiles. Among the various Spatial Transcriptomics techniques available, Visium has emerged as the most widely…

Computer Vision and Pattern Recognition · Computer Science 2025-09-05 Daniela Ruiz , Paula Cárdenas , Leonardo Manrique , Daniela Vega , Gabriel M. Mejia , Pablo Arbeláez

Missing data scenarios are very common in ML applications in general and time-series/sequence applications are no exceptions. This paper pertains to a novel Recurrent Neural Network (RNN) based solution for sequence prediction under missing…

Machine Learning · Computer Science 2022-08-19 Soumen Pachal , Avinash Achar

This paper investigates the adaptive identification and prediction problems for stochastic dynamical systems with saturated observations, which arise from various fields in engineering and social systems, but up to now still lack…

Systems and Control · Electrical Eng. & Systems 2023-09-19 Lantian Zhang , Lei Guo

Unsupervised Domain Adaptation for Remote Sensing Semantic Segmentation (UDA-RSSeg) addresses the challenge of adapting a model trained on source domain data to target domain samples, thereby minimizing the need for annotated data across…

Computer Vision and Pattern Recognition · Computer Science 2024-11-20 Shuchang Lyu , Qi Zhao , Guangliang Cheng , Yiwei He , Zheng Zhou , Guangbiao Wang , Zhenwei Shi

Deep learning-based nuclei segmentation and classification in pathology images typically rely on large-scale pixel-level manual annotations, which are costly and difficult to obtain across diverse tissues and staining conditions. To address…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Kazuya Nishimura , Ryoma Bise , Haruka Hirose , Yasuhiro Kojima

The high-throughput short-reads RNA-seq protocols often produce paired-end reads, with the middle portion of the fragments being unsequenced. We explore if the full-length fragments can be computationally reconstructed from the sequenced…

Genomics · Quantitative Biology 2023-10-06 Xiang Li , Mingfu Shao

High-throughput RNA-sequencing (RNA-seq) technologies are powerful tools for understanding cellular state. Often it is of interest to quantify and summarize changes in cell state that occur between experimental or biological conditions.…

Methodology · Statistics 2021-02-16 Andrew Jones , F. William Townes , Didong Li , Barbara E. Engelhardt

Methods for global measurement of transcript abundance such as microarrays and RNA-Seq generate datasets in which the number of measured features far exceeds the number of observations. Extracting biologically meaningful and experimentally…

Methodology · Statistics 2022-06-22 Lei Ding , Gabriel E. Zentner , Daniel J. McDonald