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This paper introduces ESPnet-SPK, a toolkit designed with several objectives for training speaker embedding extractors. First, we provide an open-source platform for researchers in the speaker recognition community to effortlessly build…

Sequencing costs currently prohibit the application of single-cell mRNA-seq to many biological and clinical analyses. Targeted single-cell mRNA-sequencing reduces sequencing costs by profiling reduced gene sets that capture biological…

Genomics · Quantitative Biology 2022-02-15 Xiaoqiao Chen , Sisi Chen , Matt Thomson

Paraphasias are speech errors that are often characteristic of aphasia and they represent an important signal in assessing disease severity and subtype. Traditionally, clinicians manually identify paraphasias by transcribing and analyzing…

Sound · Computer Science 2023-12-19 Matthew Perez , Duc Le , Amrit Romana , Elise Jones , Keli Licata , Emily Mower Provost

Recent progress on salient object detection mainly aims at exploiting how to effectively integrate multi-scale convolutional features in convolutional neural networks (CNNs). Many popular methods impose deep supervision to perform…

Computer Vision and Pattern Recognition · Computer Science 2021-01-21 Yun Liu , Ming-Ming Cheng , Xinyu Zhang , Guang-Yu Nie , Meng Wang

Quantization is commonly used in Deep Neural Networks (DNNs) to reduce the storage and computational complexity by decreasing the arithmetical precision of activations and weights, a.k.a. tensors. Efficient hardware architectures employ…

Machine Learning · Computer Science 2023-11-23 Bahareh Khabbazan , Marc Riera , Antonio González

Single-cell RNA sequencing (scRNA-seq) is widely used to reveal heterogeneity in cells, which has given us insights into cell-cell communication, cell differentiation, and differential gene expression. However, analyzing scRNA-seq data is a…

Machine Learning · Computer Science 2023-06-27 Yuta Hozumi , Gu-Wei Wei

Training datasets are crucial for convolutional neural network-based algorithms, which directly impact their overall performance. As such, using a well-structured dataset that has minimum level of bias is always desirable. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2021-06-29 Ekberjan Derman

Single-cell RNA sequencing (scRNA-seq) is powerful technology that allows researchers to understand gene expression patterns at the single-cell level. However, analysing scRNA-seq data is challenging due to issues and biases in data…

Genomics · Quantitative Biology 2023-12-14 Jinlu Liu , Sara Wade , Natalia Bochkina

Text segmentation is a prerequisite in many real-world text-related tasks, e.g., text style transfer, and scene text removal. However, facing the lack of high-quality datasets and dedicated investigations, this critical prerequisite has…

Computer Vision and Pattern Recognition · Computer Science 2020-12-01 Xingqian Xu , Zhifei Zhang , Zhaowen Wang , Brian Price , Zhonghao Wang , Humphrey Shi

Profiled side-channel analysis (SCA) leverages leakage from cryptographic implementations to extract the secret key. When combined with advanced methods in neural networks (NNs), profiled SCA can successfully attack even those crypto-cores…

Cryptography and Security · Computer Science 2022-10-18 Rabin Yu Acharya , Fatemeh Ganji , Domenic Forte

Compressed sensing can decrease scanning transmission electron microscopy electron dose and scan time with minimal information loss. Traditionally, sparse scans used in compressed sensing sample a static set of probing locations. However,…

Machine Learning · Computer Science 2021-03-12 Jeffrey M. Ede

Span-based joint extraction simultaneously conducts named entity recognition (NER) and relation extraction (RE) in text span form. Recent studies have shown that token labels can convey crucial task-specific information and enrich token…

Computation and Language · Computer Science 2022-07-19 Bin Ji , Shasha Li , Jie Yu , Jun Ma , Huijun Liu

High throughput technologies have become the practice of choice for comparative studies in biomedical applications. Limited number of sample points due to sequencing cost or access to organisms of interest necessitates the development of…

Methodology · Statistics 2018-07-17 Ariana Broumand , Siamak Zamani Dadaneh

Single-cell RNA sequencing (scRNA-seq) enables single-cell transcriptomic profiling, revealing cellular heterogeneity and rare populations. Recent deep learning models like Geneformer and Mouse-Geneformer perform well on tasks such as…

Genomics · Quantitative Biology 2025-07-11 Yuki Nishio , Takayoshi Yamashita , Keita Ito , Tsubasa Hirakawa , Hironobu Fujiyoshi

High-throughput sequencing is now regularly used for studies of the transcriptome (RNA-seq), particularly for comparisons among experimental conditions. For the time being, a limited number of biological replicates are typically considered…

Applications · Statistics 2013-06-18 Andrea Rau , Guillemette Marot , Florence Jaffrézic

Next-generation sequencing technologies generate millions of short sequence reads, which are usually aligned to a reference genome. In many applications, the key information required for downstream analysis is the number of reads mapping to…

Genomics · Quantitative Biology 2016-07-26 Yang Liao , Gordon K Smyth , Wei Shi

Motivation: Single cell RNA sequencing (scRNA-seq) data makes studying the development of cells possible at unparalleled resolution. Given that many cellular differentiation processes are hierarchical, their scRNA-seq data is expected to be…

Quantitative Methods · Quantitative Biology 2022-04-25 Quentin Garrido , Sebastian Damrich , Alexander Jäger , Dario Cerletti , Manfred Claassen , Laurent Najman , Fred Hamprecht

Single-cell RNA sequencing (scRNA-seq) and spatially-resolved imaging/sequencing technologies have revolutionized biomedical research. On one hand, scRNA-seq provides information about a large portion of the transcriptome for individual…

Computational Engineering, Finance, and Science · Computer Science 2026-03-24 Arezou Rahimi , Luis A. Vale-Silva , Maria Faelth Savitski , Jovan Tanevski , Julio Saez-Rodriguez

The semi-airborne transient electromagnetic method (SATEM) is capable of conducting rapid surveys over large-scale and hard-to-reach areas. However, the acquired signals are often contaminated by complex noise, which can compromise the…

Machine Learning · Computer Science 2025-03-31 Shuang Wang , Ming Guo , Xuben Wang , Fei Deng , Lifeng Mao , Bin Wang , Wenlong Gao

RNA-Seq data characteristically exhibits large variances, which need to be appropriately accounted for in the model. We first explore the effects of this variability on the maximum likelihood estimator (MLE) of the overdispersion parameter…

Methodology · Statistics 2015-12-03 Luis Leon-Novelo , Claudio Fuentes , Sarah Emerson