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The structure of a complex network plays a crucial role in determining its dynamical properties. In this work, we show that the the degree to which a network is directed and hierarchically organised is closely associated with the degree to…

In many areas such as computational biology, finance or social sciences, knowledge of an underlying graph explaining the interactions between agents is of paramount importance but still challenging. Considering that these interactions may…

Signal Processing · Electrical Eng. & Systems 2021-04-29 Mircea Moscu , Ricardo A. Borsoi , Cédric Richard , José-Carlos M. Bermudez

The number of observable degrees of freedom is typically limited in experiments. Here, we consider discrete Markov networks in which an observer has access to a few visible transitions and the waiting times between these transitions.…

Statistical Mechanics · Physics 2025-09-26 Alexander M. Maier , Udo Seifert , Jann van der Meer

Discriminating between correct and incorrect substrates is a core process in biology but how is energy apportioned between the conflicting demands of accuracy ($\mu$), speed ($\sigma$) and total entropy production rate ($P$)? Previous…

Molecular Networks · Quantitative Biology 2019-06-18 Felix Wong , Ariel Amir , Jeremy Gunawardena

We study the problem of identifying different behaviors occurring in different parts of a large heterogenous network. We zoom in to the network using lenses of different sizes to capture the local structure of the network. These network…

Social and Information Networks · Computer Science 2019-01-29 Kshiteesh Hegde , Malik Magdon-Ismail

Understanding the mathematical properties of graphs underling biological systems could give hints on the evolutionary mechanisms behind these structures. In this article we perform a complete statistical analysis over thousands of graphs…

Molecular Networks · Quantitative Biology 2019-08-29 D. Gamermann , J. Triana , R. Jaime

Identifying unusual brain activity is a crucial task in neuroscience research, as it aids in the early detection of brain disorders. It is common to represent brain networks as graphs, and researchers have developed various graph-based…

Machine Learning · Computer Science 2024-10-04 Sadaf Sadeghian , Xiaoxiao Li , Margo Seltzer

Graph theoretical approach has proved an effective tool to understand, characterize and quantify the complex brain network. However, much less attention has been paid to methods that quantitatively compare two graphs, a crucial issue in the…

Neurons and Cognition · Quantitative Biology 2019-08-29 Ahmad Mheich , Fabrice Wendling , Mahmoud Hassan

Network models are used to study interconnected systems across many physical, biological, and social disciplines. Such models often assume a particular network-generating mechanism, which when fit to data produces estimates of…

Social and Information Networks · Computer Science 2022-01-17 Ryan E. Langendorf , Matthew G. Burgess

Networks constitute efficient tools for assessing universal features of complex systems. In physical contexts, classical as well as quantum, networks are used to describe a wide range of phenomena, such as phase transitions, intricate…

Quantum Physics · Physics 2016-01-22 Jaroslav Novotný , Gernot Alber , Igor Jex

Graphs are widely used for describing systems made up of many interacting components and for understanding the structure of their interactions. Various statistical models exist, which describe this structure as the result of a combination…

Methodology · Statistics 2021-06-28 Louis Duvivier , Rémy Cazabet , Céline Robardet

Motivation: Molecular interaction networks summarize complex biological processes as graphs, whose structure is informative of biological function at multiple scales. Simultaneously, omics technologies measure the variation or activity of…

Quantitative Methods · Quantitative Biology 2020-12-24 Ramin Hasibi , Tom Michoel

Microarrays have become extremely useful for analysing genetic phenomena, but establishing a relation between microarray analysis results (typically a list of genes) and their biological significance is often difficult. Currently, the…

Quantitative Methods · Quantitative Biology 2007-05-23 Franck Rapaport , Andrei Zinovyev , Marie Dutreix , Emmanuel Barillot , Jean-Philippe Vert

In this paper, we consider the problem of exploring structural regularities of networks by dividing the nodes of a network into groups such that the members of each group have similar patterns of connections to other groups. Specifically,…

Physics and Society · Physics 2015-05-30 Hua-Wei Shen , Xue-Qi Cheng , Jia-Feng Guo

The study of time-varying (dynamic) networks (graphs) is of fundamental importance for computer network analytics. Several methods have been proposed to detect the effect of significant structural changes in a time series of graphs. The…

Social and Information Networks · Computer Science 2017-07-25 Peter Wills , Francois G. Meyer

Complex dynamical systems are often modeled as networks, with nodes representing dynamical units which interact through the network's links. Gene regulatory networks, responsible for the production of proteins inside a cell, are an example…

Statistical Mechanics · Physics 2009-09-30 Zoran Levnajić

Functional brain networks exhibit topological structures that reflect neural organization; however, statistical comparison of these networks is challenging for several reasons. This paper introduces a topologically invariant permutation…

Neurons and Cognition · Quantitative Biology 2025-12-30 Sixtus Dakurah

One of the first steps in applications of statistical network analysis is frequently to produce summary charts of important features of the network. Many of these features take the form of sequences of graph statistics counting the number…

Statistics Theory · Mathematics 2025-02-14 Jonathan R. Stewart

Graphlets are induced subgraph patterns that are crucial to the understanding of the structure and function of a large network. A lot of efforts have been devoted to calculating graphlet statistics where random walk based approaches are…

Social and Information Networks · Computer Science 2020-05-12 Simiao Jiao , Zihui Xue , Xiaowei Chen , Yuedong Xu

In random graph models, the degree distribution of an individual node should be distinguished from the (empirical) degree distribution of the graph that records the fractions of nodes with given degree. We introduce a general framework to…

Social and Information Networks · Computer Science 2018-11-14 Siddharth Pal , Armand M. Makowski