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Purpose: This work addresses the detection of Helicobacter pylori (H. pylori) in histological images with immunohistochemical staining. This analysis is a time demanding task, currently done by an expert pathologist that visually inspects…

Image and Video Processing · Electrical Eng. & Systems 2024-12-19 Pau Cano , Eva Musulen , Debora Gil

Motivation: Bacteriophages are viruses infecting bacteria. Being key players in microbial communities, they can regulate the composition/function of microbiome by infecting their bacterial hosts and mediating gene transfer. Recently,…

Genomics · Quantitative Biology 2022-08-15 Jiayu Shang , Xubo Tang , Ruocheng Guo , Yanni Sun

We present a SNAIL-based parametric amplifier that integrates a lumped-element impedance matching network for increased bandwidth and an on-chip pump-port filter for efficient pump delivery. The amplifier is fabricated using a single-layer…

Quantum Physics · Physics 2025-05-06 V. R. Joshi , S. Hazra , A. Z. Ding , A. Miano , W. Dai , G. Umasankar , A. Kottandavida , G. Liu , L. Frunzio , M. H. Devoret

Fluorescence detection is a commonly used analytical method with the advantages of fast response, good selectivity and low destructiveness. However, fluorescence detection, a single-mode detection method, has some limitations, such as…

Optics · Physics 2024-06-06 Wei Zheng

Raman spectroscopy is a promising tool for microbial identification, yet its implementation in microbiology and clinical workflow is still restricted due to the accompanying additional preparation required to focus on microbial signals.…

Quantitative Methods · Quantitative Biology 2026-03-19 Jeong Hee Kim , Jia Dong , Marissa Morales , Loza Tadesse

Chemoreceptors McpB and McpC in Salmonella enterica have been reported to promote chemotaxis in LB motility-plate assays. Of the chemicals tested as potential effectors of these receptors, the only response was towards L-cysteine and its…

Molecular Networks · Quantitative Biology 2013-04-16 Milena D. Lazova , Mitchell T. Butler , Thomas S. Shimizu , Rasika M. Harshey

The SPIDER H-/D- ion source is currently in operation in the Neutral Beam Test facility (NBTF) at Consorzio RFX (Padova, Italy) to prove the possibility of generating up to 40 A of negative ions, with a maximum extracted current density of…

Plasma Physics · Physics 2022-11-11 M. Barbisan , S. Cristofaro , L. Zampieri , R. Pasqualotto , A. Rizzolo

The objective of this project is to develop an automated device used to spot protein samples on a hydrophobic membrane to be used for the patented electrophoresis method developed by Chang and Yonan in 2008 [1]. This novel method performs…

Other Quantitative Biology · Quantitative Biology 2023-03-13 Christopher M. Altenderfer , Frank N. Chang , Parsaoran Hutapea

Camera traps, combined with AI, have emerged as a way to achieve automated, scalable biodiversity monitoring. However, the passive infrared (PIR) sensors that trigger camera traps are poorly suited for detecting small, fast-moving…

Quantitative Methods · Quantitative Biology 2025-02-18 Ross Gardiner , Sareh Rowands , Benno I. Simmons

Creating plasmonic nanoparticles on a tapered optical fiber tip enables a remote SERS sensing probe, ideal for challenging sampling scenarios like biological tissue, specific cells, on-site environmental monitoring, and deep brain…

The primary goal of the novel photosensor technology called ABALONETM (U.S. Pat. 9,064,678) has been to enable the next-generation of astroparticle physics experiments to open new windows on the universe with large-area detectors of…

Instrumentation and Detectors · Physics 2023-08-08 Ivan Ferenc Šegedin , Marija Šegedin Ferenc , Daniel Ferenc

Structurally nanoengineered antimicrobial peptide polymers (SNAPPs) are emerging as promising selective agents against bacterial membranes. In this study, we used all atom molecular dynamics simulation techniques to investigate the…

Biomolecules · Quantitative Biology 2025-11-11 Amal Jayawardena , Andrew Hung , Greg Qiao , Neil OBrien-Simpson , Elnaz Hajizadeh

We propose an improved structure of an optical biosensor based on a photonic crystal (PC) with a defect layer (DL), which can detect the concentration of SARS-CoV-2 in water by defect mode (DM) shift. We investigated 4 types of defective…

Optics · Physics 2022-08-10 I. M. Efimov , N. A. Vanyushkin , A. H. Gevorgyan

A central feature of vertebrate immune response is affinity maturation, wherein antibody-producing B cells undergo evolutionary selection in microanatomical structures called germinal centers, which form in secondary lymphoid organs upon…

Populations and Evolution · Quantitative Biology 2024-02-15 Bertrand Ottino-Loffler , Gabriel Victora

Time series anomaly detection is critical for modern digital infrastructures, yet existing methods lack systematic cross-domain evaluation. We present a comprehensive forecasting-based framework unifying classical methods (Holt-Winters,…

Machine Learning · Computer Science 2025-10-14 Mohammad Karami , Mostafa Jalali , Fatemeh Ghassemi

There exists an urgent need for efficient tools in disease surveillance to help model and predict the spread of disease. The transmission of insect-borne diseases poses a serious concern to public health officials and the medical and…

Robotics · Computer Science 2020-09-01 Keran Ye , Gustavo J. Correa , Tom Guda , Hanzhe Teng , Anandasankar Ray , Konstantinos Karydis

Semantic segmentation usually benefits from global contexts, fine localisation information, multi-scale features, etc. To advance Transformer-based segmenters with these aspects, we present a simple yet powerful semantic segmentation…

Computer Vision and Pattern Recognition · Computer Science 2022-12-07 Lihua Fu , Haoyue Tian , Xiangping Bryce Zhai , Pan Gao , Xiaojiang Peng

This paper presents a transformer-based approach to solving the SympTEMIST named entity recognition (NER) and entity linking (EL) tasks. For NER, we fine-tune a RoBERTa-based (1) token-level classifier with BiLSTM and CRF layers on an…

Computation and Language · Computer Science 2026-04-09 Georgi Grazhdanski , Sylvia Vassileva , Ivan Koychev , Svetla Boytcheva

Sensor selection is critical for state estimation, control and monitoring of nonlinear processes. However, evaluating the performance of each possible combination of $m$ out of $n$ sensors is impractical unless $m$ and $n$ are small. In…

Systems and Control · Electrical Eng. & Systems 2022-08-02 Siyu Liu , Xunyuan Yin , Zhichao Pan , Jinfeng Liu

Biosensors are an essential tool for medical diagnostics, environmental monitoring and food safety. Typically, biosensors are designed to detect specific analytes through functionalization with the appropriate capture agents. However, the…

Medical Physics · Physics 2023-09-26 Simon J. Ward , Tengfei Cao , Xiang Zhou , Catie Chang , Sharon M. Weiss