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We propose a water-immersed nucleobase-functionalized suspended graphene nanoribbon as an intrinsically selective device for nucleotide detection. The proposed sensing method combines Watson-Crick selective base pairing with graphene's…
Rapid antimicrobial susceptibility testing (AST) is urgently needed for treating infections with correct antibiotics and slowing down the emergence of antibiotic-resistant bacteria. Here, we report a phenotypic platform that rapidly…
A new segmented compressed sampling method for analog-to-information conversion (AIC) is proposed. An analog signal measured by a number of parallel branches of mixers and integrators (BMIs), each characterized by a specific random sampling…
This paper presents a comprehensive study on a novel multilayer surface plasmon resonance (SPR) biosensor designed for detecting trace-level toxins in liquid samples with exceptional precision and efficiency. Leveraging the Kretschmann…
Sequence coverage in MS analysis of protein digestion-derived peptides is a key issue for detailed characterization of proteins or identification at low quantities. In gel-based proteomics studies, the sequence coverage greatly depends on…
We use the power density spectra obtained by fluctuation-enhanced sensing of bacterial odors (Escherichia coli and Anthrax-surrogate Bacillus subtilis) to generate new, highly distinguishable, types of patterns based on the average slope of…
There is growing interest in using machine learning (ML) to support clinical diagnosis, but most approaches rely on static, fully observed datasets and fail to reflect the sequential, resource-aware reasoning clinicians use in practice.…
Anomaly detectors are widely used in industrial manufacturing to detect and localize unknown defects in query images. These detectors are trained on anomaly-free samples and have successfully distinguished anomalies from most normal…
Stuttering is a neurodevelopmental speech disorder characterized by common speech symptoms such as pauses, exclamations, repetition, and prolongation. Speech-language pathologists typically assess the type and severity of stuttering by…
In haptic object discrimination, the effect of gripper embodiment, action parameters, and sensory channels has not been systematically studied. We used two anthropomorphic hands and two 2-finger grippers to grasp two sets of deformable…
SCUBA-2 is the next-generation replacement for SCUBA (Sub-millimetre Common User Bolometer Array) on the James Clerk Maxwell Telescope. Operating at 450 and 850 microns, SCUBA-2 fills the focal plane of the telescope with fully-sampled,…
Rapid antibiotic susceptibility tests (ASTs) are essential for quick selection of effective drugs to treat bacterial infections at an early stage. However, the most widely used phenotypic ASTs in clinical practice often require 24 - 48…
The immuno-infrared sensor detects target proteins in solution. Exemplary, the initial misfolding of amyloid beta (Abeta) peptides in blood is measured, enabling early risk prediction of Alzheimer's disease in the preclinical stage.…
We propose a novel approach to detect the binding between proteins making use of the anomalous diffraction of natively present heavy elements inside the molecule 3D structure. In particular, we suggest considering sulfur atoms contained in…
An efficient method is reported for rapid identification of bacterial or mycobacterial infection in a suspected clinical/biological sample. The method is based on the fact that the ring methylene protons of cyclic fatty acids (constituting…
Breast cancer (BC) remains a significant health threat, with no long-term cure currently available. Early detection is crucial, yet mammography interpretation is hindered by high false positives and negatives. With BC incidence projected to…
Photonic crystal fiber (PCF)-based plasmonic sensors have gained considerable attention because of their highly sensitive performance and broad range of sensing regimes. In this work, a relatively simple ultra-sensitive PCF-based surface…
Associated Particle Imaging (API) is a nuclear technique that allows for the nondestructive determination of 3D isotopic distributions. The technique is based on the detection of the alpha particles associated with the neutron emitted in…
Large language models (LLMs) have shown remarkable advancements in chemistry and biomedical research, acting as versatile foundation models for various tasks. We introduce AMP-Designer, an LLM-based approach for swiftly designing novel…
A Rapid and cost-effective method for detecting bacterial cells on surfaces is critical to protect public health from various aspects, including food safety, clinical hygiene, and pharmacy quality. Herein, we first established an optical…