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As an important property of porous membranes, the surface charge property determines many ionic behaviors of nanopores, such as ionic conductance and selectivity. Based on the dependence of electric double layers on bulk concentrations,…

Chemical Physics · Physics 2024-02-08 Jiakun Zhuang , Long Ma , Yinghua Qiu

With the continued improvement of sequencing technologies, the prospect of genome-based medicine is now at the forefront of scientific research. To realize this potential, however, we need a revolutionary sequencing method for the…

Biological Physics · Physics 2008-01-03 Michael Zwolak , Massimiliano Di Ventra

A fabrication method for positioning and embedding a single-walled carbon nanotube (SWNT) across the diameter of a solid state nanopore is presented. Chemical vapor deposition (CVD) is used to grow SWNTs over arrays of focused ion beam…

Biological Physics · Physics 2013-08-07 E. S. Sadki , S. Garaj , D. Vlassarev , J. A. Golovchenko , D. Branton

The characterization of protein-nanoparticle assemblies in solution remains a challenge. We demonstrate a technique based on a graphene microelectrode for structural-functional analysis of model systems composed of nanoparticles enclosed in…

Dielectrophoresis can potentially be used as an efficient trapping tool in the fabrication of molecular devices. For nanoscale objects, however, the Brownian motion poses a challenge. We show that the use of carbon nanotube electrodes makes…

Recently solid state nanopores nanogaps have generated a lot of interest in ultrafast DNA sequencing. However, there are challenges to slow down the DNA translocation process to achieve a single nucleobase resolution. A series of…

Applied Physics · Physics 2020-04-24 Rameshwar L. Kumawat , Priyanka Garg , Gargee Bhattacharyya , Biswarup Pathak

Expanding genetic codes from natural standard nucleotides to artificial non-standard nucleotides marks a significant advancement in synthetic biology, with profound implications for biotechnology and medicine. Decoding the biological…

Genomics · Quantitative Biology 2024-09-17 Hyunjin Shim

In nanopore technology, the development of multiplexed detection and release platforms with high spatial and temporal resolution remains a significant challenge due to the difficulty in distinguishing signals originating from different…

Applied Physics · Physics 2025-10-16 Ali Douaki , Shukun Weng , Silvia Dante , Nako Nakatsuka , Makusu Tsutsui , Roman Krahne , Denis Garoli

Various metallic structures of complex shape resembling living plant organisms (biomimetics) are produced as a result of selfassembly of nanowires growing on porous membranes in the course of pulse current electrodeposition. These…

Solid polymer electrolytes for lithium batteries promise improvements in safety and energy density if their conductivity can be increased. Nanostructured block copolymer electrolytes specifically have the potential to provide both good…

Electroosmosis is a fascinating effect where liquid motion is induced by an applied electric field. Counter ions accumulate in the vicinity of charged surfaces, triggering a coupling between liquid mass transport and external electric…

We describe several unexpected phenomena, caused by a solid-solid phase transition (gel-to-crystal) typical for all main classes of lipid substances - phospholipids, triglycerides, diglycerides, alkanes, etc. We discovered that this…

Materials Science · Physics 2020-08-26 Diana Cholakova , Desislava Glushkova , Slavka Tcholakova , Nikolai Denkov

Bipolar nanopores, with asymmetric charge distributions, can induce significant ionic current rectification (ICR) at ultra-short lengths, finding potential applications in nanofluidic devices, energy conversion, and other related fields.…

Chemical Physics · Physics 2024-10-29 Hongwen Zhang , Long Ma , Chao Zhang , Yinghua Qiu

The Helium Ion Microscope (HIM) has the capability to image small features with a resolution down to 0.35 nm due to its highly focused gas field ionization source and its small beam-sample interaction volume. In this work, the focused…

Applied Physics · Physics 2018-05-02 D. Emmrich , A. Beyer , A. Nadzeyka , S. Bauerdick , J. C. Meyer , J. Kotakoski , A. Gölzhäuser

The determination of a patient's DNA sequence can, in principle, reveal an increased risk to fall ill with particular diseases [1,2] and help to design "personalized medicine" [3]. Moreover, statistical studies and comparison of genomes [4]…

Freestanding semiconductor nanowires have opened up new possibilities for semiconductor devices, enabling geometries, material combinations and strain states which were not previously possible. Along these lines, spontaneous bending in…

Instrumentation and Detectors · Physics 2021-07-28 Spencer W. McDermott , Ryan B. Lewis

It is shown that porous spherical particles can be obtained via the freezing of silica nanoparticle aqueous suspensions emulsified in a continuous oil phase. After two freeze-thaw cycles, nanoparticles turn aggregated into flocculated…

Soft Condensed Matter · Physics 2020-05-26 Mathieu Nespoulous , Mickaël Antoni , Carine Chassigneux , Renaud Denoyel

Low dimensional quantum fluids, where one can probe the effects of enhanced thermal and quantum fluctuations on macroscopic quantum wavefunctions, can be experimentally realized through transverse physical confinement of superfluid helium…

Mesoscale and Nanoscale Physics · Physics 2026-02-26 Sutirtha Paul , Taras Lakoba , Paul E. Sokol , Adrian Del Maestro

We use hexagonal mesophases made of oil-swollen surfactant-stabilized tubes arranged on a triangular lattice in water and doped with metallic salts as templates for the radiolytic synthesis of nanostructures. The nanostructures formed in…

Methods for reducing and directly controlling the speed of DNA through a nanopore are needed to enhance sensing performance for direct strand sequencing and detection/mapping of sequence-specific features. We have created a method for…

Biological Physics · Physics 2018-11-28 Xu Liu , Yuning Zhang , Roland Nagel , Walter Reisner , William B. Dunbar