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Simple method of producing high voltage pulses with short rising times based on electrostatic induction in external capacitor used for pulse power applications is proposed. The circuit has simple structure and contains minimum number of…

Applied Physics · Physics 2018-06-26 Taku Saiki

The focus of this paper is a proof of concept, machine learning (ML) pipeline that extracts heart rate from pressure sensor data acquired on low-power edge devices. The ML pipeline consists an upsampler neural network, a signal quality…

Machine Learning · Computer Science 2022-08-18 Preetam Anbukarasu , Shailesh Nanisetty , Ganesh Tata , Nilanjan Ray

Fluid dynamics plays a crucial role in various multiphysics applications, including energy systems, electronics cooling, and biomedical engineering. Developing models for complex coupled systems can be challenging and time-consuming. In…

Computational Engineering, Finance, and Science · Computer Science 2024-12-09 Markus Lohmayer , Michael Kraus , Sigrid Leyendecker

FLASH-RT has proven beneficial in preclinical studies. However, the lack of accurate real time 2D dosimetry is a limiting factor. In this work, an innovative solution for 2D real time dosimetry in UHDR electron beams is presented. The…

High-density microfluidics is becoming an important experimental platform for studying complex biological systems such as synthetic gene regulatory networks, molecular biocomputating of engineered cells, distributing rapid point-of-care…

Biological Physics · Physics 2021-07-21 Sankar Raju Narayanasamy , Ramakrishna Vasireddi , Hoi-Ying Holman

Electroporation method is a useful tool for delivering drugs into various diseased tissues in the human body. As a result of an applied electric field, drug particles enter the intracellular compartment through the temporarily permeabilized…

Tissues and Organs · Quantitative Biology 2022-08-10 Nilay Mondal , K. S. Yadav , D. C. Dalal

A picosecond pulse generator based on a pair of step recovery diodes (SRD), leveraging the transient response of the SRD PN junction and controlling the pulse width by a resistor, is proposed. We first explain the operation principle of the…

Instrumentation and Detectors · Physics 2017-10-17 Lianfeng Zou , Shulabh Gupta , Christophe Caloz

We have used a field-penetration method to measure thermodynamic compressibility of a moderately interacting two-dimensional electron system ($r_{s}$ $\approx$ 0.5-3) in a three terminal GaAs/AlGaAs device, fabricated with an epitaxial…

Strongly Correlated Electrons · Physics 2009-09-29 S. C. Dultz , B. Alavi , H. W. Jiang

Curable hydrogels have tunable properties that make them well-suited for applications in drug delivery, cell therapies, and 3D bioprinting. Advances in microfluidic droplet generation enable rapid fabrication of polymer-filled droplets.…

Fluid Dynamics · Physics 2025-12-02 Sabrina Marnoto , Avi J. Patel , Sara M. Hashmi

This paper details the development of an integrated AC electro-osmotic (ACEO) microfluidic pump for dilute electrolytes consisting of a long serpentine microchannel lined with three dimensional (3D) stepped electrode arrays. Using low AC…

Fluid Dynamics · Physics 2009-08-06 Chien-Chih Huang , Martin Z. Bazant , Todd Thorsen

Due to patient privacy protection concerns, machine learning research in healthcare has been undeniably slower and limited than in other application domains. High-quality, realistic, synthetic electronic health records (EHRs) can be…

Machine Learning · Computer Science 2023-02-10 Huan He , Shifan Zhao , Yuanzhe Xi , Joyce C Ho

Polydimethylsiloxane (PDMS) microfluidic devices have become a standard tool for engineering cells and multicellular networks in vitro. However, the reservoirs, or through-holes where cells access the devices, are usually fabricated…

Applied Physics · Physics 2020-12-02 Taiki Takemuro , Hideaki Yamamoto , Shigeo Sato , Ayumi Hirano-Iwata

Electrically actuated continuous motion of a water droplet over PDMS-coated single active electrode is analyzed from detailed modeling and experiments. In an experiment, continuous motion of the droplet is achieved when it is located over…

Fluid Dynamics · Physics 2023-05-02 Supriya Upadhyay , K. Muralidhar

The use of very high energy electron (VHEE) beams for radiotherapy has been actively studied for over two decades due to their advantageous dose distribution, deep penetration depth and great potential of ultra-high dose-rate irradiation.…

Medical Physics · Physics 2026-04-30 Bing Zhou , Zhiyuan Guo , Yang Wan , Shuang Liu , Jianfei Hua , Wei Lu

Stimulus-responsive DNA-hydrogels with swelling capabilities are a promising class of materials for biomedical applications such as drug delivery and biosensing. However, translation of these systems to microscale applications requires…

Irradiations at Ultra High Dose Rate (UHDR) regimes, exceeding 40 Gy/s in single fractions lasting less than 200 ms, have shown an equivalent antitumor effect compared to conventional radio-therapy with reduced harm to normal tissues. This…

Spatially resolved electron energy-loss spectroscopy (EELS) in a scanning transmission electron microscope (STEM) has been used to investigate as fluidic phase in nanoubbles embedded in a metallic Pd90Pt10 matrix. Using the 1s->2p…

Materials Science · Physics 2016-08-14 D. Taverna , M. Kociak , O. Stéphan , A. Fabre , E. Finot , B. Décamps , C. Colliex

Pulmonary drug delivery systems rely on inhalation of drug-laden aerosols produced from aerosol generators such as inhalers, nebulizers etc. On deposition, the drug molecules diffuse in the mucus layer and are also subjected to mucociliary…

Tissues and Organs · Quantitative Biology 2022-01-14 Aranyak Chakravarty , Mahesh V. Panchagnula , Alladi Mohan , Neelesh A. Patankar

We present Haptic Light-Emitting Diodes (HLEDs), luminous thermopneumatic actuators that directly convert pulsed light into mechanical forces and displacements. Each device packages a miniature surface-mount LED in a gas-filled cavity that…

Human-Computer Interaction · Computer Science 2026-04-29 Max Linnander , Yon Visell

Droplet-based microfluidics systems have become widely used in recent years thanks to their advantages, varying from the possibility of handling small fluid volumes to directly synthesizing and encapsulating various living forms for…