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We consider the evolution of large but finite populations on arbitrary fitness landscapes. We describe the evolutionary process by a Markov, Moran process. We show that to $\mathcal O(1/N)$, the time-averaged fitness is lower for the finite…

Populations and Evolution · Quantitative Biology 2015-06-04 Dirk M. Lorenz , Jeong-Man Park , Michael W. Deem

We study Eigen's model of quasi-species, characterized by sequences that replicate with a specified fitness and mutate independently at single sites. The evolution of the population vector in time is then closely related to that of quantum…

Statistical Mechanics · Physics 2021-02-12 Saumya Shivam , Christopher L. Baldwin , John Barton , Mehran Kardar , S. L. Sondhi

In this work we study the stability properties of the equilibrium points of deterministic epidemic models with nonconstant population size. Models with nonconstant population have been studied in the past only in particular cases, two of…

Optimization and Control · Mathematics 2022-02-25 Florin Avram , Rim Adenane , Lasko Basnarkov , Gianluca Bianchin , Dan Goreac , Andrei Halanay

We study a classical multitype Galton--Watson process with mutation and selection. The individuals are sequences of fixed length over a finite alphabet. On the sharp peak fitness landscape together with independent mutations per locus, we…

Probability · Mathematics 2016-07-01 Joseba Dalmau

This survey concerns the study of quasi-stationary distributions with a specific focus on models derived from ecology and population dynamics. We are concerned with the long time behavior of different stochastic population size processes…

Probability · Mathematics 2012-12-05 Sylvie Méléard , Denis Villemonais

We consider a integro-differential nonlinear model that describes the evolution of a population structured by a quantitative trait. The interactions between traits occur from competition for resources whose concentrations depend on the…

Analysis of PDEs · Mathematics 2011-12-05 Nicolas Champagnat , Pierre-Emmanuel Jabin

An infinite population of point entities dwelling in the habitat $X=\mathds{R}^d$ is studied. Its members arrive at and depart from $X$ at random. The departure rate has a term corresponding to a logistic-type interaction between the…

Probability · Mathematics 2025-11-11 Yuri Kozitsky , Michael Röckner

Muller's ratchet, in its prototype version, models a haploid, asexual population whose size~$N$ is constant over the generations. Slightly deleterious mutations are acquired along the lineages at a constant rate, and individuals carrying…

Populations and Evolution · Quantitative Biology 2025-12-05 Jan Lukas Igelbrink , Adrián González Casanova , Charline Smadi , Anton Wakolbinger

In populations competing for resources, it is natural to ask whether consuming fewer resources provides any selective advantage. To answer this question, we propose a Wright- Fisher model with two types of individuals: the inefficient…

Probability · Mathematics 2020-09-11 Adrian Gonzalez Casanova , Veronica Miro Pina , Juan Carlos Pardo

There is a deep connection between the ground states of transverse-field spin systems and the late-time distributions of evolving viral populations -- within simple models, both are obtained from the principal eigenvector of the same…

Statistical Mechanics · Physics 2021-01-13 C. L. Baldwin , S. Shivam , S. L. Sondhi , M. Kardar

Recombination is introduced into Eigen's theory of quasispecies evolution. Comparing numerical simulations of the rate equations in the non-recombining and recombining cases show that recombination has a strong effect on the error threshold…

Populations and Evolution · Quantitative Biology 2007-05-23 Martin Nilsson Jacobi , Mats Nordahl

Motivated by modeling the dynamics of a population living in a flowing medium where the environmental factors are random in space, we have studied an asymmetric variant of the one-dimensional contact process, where the quenched random…

Disordered Systems and Neural Networks · Physics 2015-06-16 Róbert Juhász

We formulate a general SEIR epidemic model in a heterogenous population characterized by some trait in a discrete or continuous subset of a space R d. The incubation and recovery rates governing the evolution of each homogenous…

Analysis of PDEs · Mathematics 2023-03-03 Luís Almeida , Pierre-Alexandre Bliman , Grégoire Nadin , Benoît Perthame , Nicolas Vauchelet

This paper develops a two gene, single fitness peak model for determining the equilibrium distribution of genotypes in a unicellular population which is capable of genetic damage repair. The first gene, denoted by $ \sigma_{via} $, yields a…

Statistical Mechanics · Physics 2009-11-10 Emmanuel Tannenbaum , Eugene I. Shakhnovich

Motivated by the wide range of known self-replicating systems, some far from genetics, we study a system composed by individuals having an internal dynamics with many possible states that are partially stable, with varying mutation rates.…

Biological Physics · Physics 2015-10-07 Tommaso Brotto , Guy Bunin , Jorge Kurchan

This article presents a comprehensive study of the continuous McKendrick model, which serves as a foundational framework in population dynamics and epidemiology. The model is formulated through partial differential equations that describe…

Populations and Evolution · Quantitative Biology 2026-01-23 Dragos-Patru Covei

In this review some simple models of asexual populations evolving on smooth landscapes are studied. The basic model is based on a cellular automaton, which is analyzed here in the spatial mean-field limit. Firstly, the evolution on a fixed…

Statistical Mechanics · Physics 2016-11-23 Franco Bagnoli , Michele Bezzi

This article studies the quasi-stationary behaviour of population processes with unbounded absorption rate, including one-dimensional birth and death processes with catastrophes and multi-dimensional birth and death processes, modeling…

Probability · Mathematics 2016-11-10 Nicolas Champagnat , Denis Villemonais

We apply a Lindeberg principle under the Markov process setting to approximate the Wright-Fisher model with neutral $r$-alleles using a diffusion process, deriving an error rate based on a function class distance involving fourth-order…

Probability · Mathematics 2024-07-15 Peng Chen , Jie Xiong , Lihu Xu , Jiayu Zheng

We are interested in the long time behavior of a two-type density-dependent biological population conditioned to non-extinction, in both cases of competition or weak cooperation between the two species. This population is described by a…

Probability · Mathematics 2008-11-04 Patrick Cattiaux , Sylvie Méléard
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