Related papers: An Introduction to RNA Databases
Object-oriented database systems proved very valuable at handling and administrating complex objects. In the following guidelines for embedding neural networks into such systems are presented. It is our goal to treat networks as normal data…
Predicting the secondary structure of RNA is a core challenge in computational biology, essential for understanding molecular function and designing novel therapeutics. The field has evolved from foundational but accuracy-limited…
Graph databases have become essential tools for managing complex and interconnected data, which is common in areas like social networks, bioinformatics, and recommendation systems. Unlike traditional relational databases, graph databases…
This paper reviews suggestions for changes to database technology coming from the work of many researchers, particularly those working with evolving big data. We discuss new approaches to remote data access and standards that better provide…
Deep learning has recently become very popular on account of its incredible success in many complex data-driven applications, such as image classification and speech recognition. The database community has worked on data-driven applications…
While RNA has recently been recognized as an interesting small-molecule drug target, many challenges remain to be addressed before we take full advantage of it. This emphasizes the necessity to improve our understanding of its structures…
In the burgeoning era of big data, selecting the optimal database solution has become a critical decision for organizations across every industry. Big data demands a powerful database solution. Traditionally, SQL Database, Database ruled,…
Databases play an essential role in our society today. Databases are embedded in sectors like corporations, institutions, and government organizations, among others. These databases are used for our video and audio streaming platforms,…
We describe the first DNA-based storage architecture that enables random access to data blocks and rewriting of information stored at arbitrary locations within the blocks. The newly developed architecture overcomes drawbacks of existing…
Previously, we reported on a new meta-registry for NAR published databases focusing on high-quality annotations regarding database availability and longevity. With over two years of continued manual curation, here, we report on recent…
We developed NameMyGene, a web tool and a stand alone program to easily generate putative family-based names for small RNA sequences so that laboratories can easily organize, analyze, and observe patterns from, the massive amount of data…
Ribonucleic acids (RNA) are unique in that they can store genetic information, replicate and perform catalysis. Importantly, RNA molecules are highly dynamic, and thus determining the ensemble of conformations that they populate is crucial…
The demanding requirements of the new Big Data intensive era raised the need for flexible storage systems capable of handling huge volumes of unstructured data and of tackling the challenges that traditional databases were facing. NoSQL…
The configuration database is one of the vital systems in the BaBar on-line system. It provides services for the different parts of the data acquisition system and control system, which require run-time parameters. The original design and…
Data mining is one of the most important steps of the knowledge discovery in databases process and is considered as significant subfield in knowledge management. Research in data mining continues growing in business and in learning…
Science is a social process with far-reaching impact on our modern society. In the recent years, for the first time we are able to scientifically study the science itself. This is enabled by massive amounts of data on scientific…
The subcellular localization of RNAs, including long non-coding RNAs (lncRNAs), messenger RNAs (mRNAs), microRNAs (miRNAs) and other smaller RNAs, plays a critical role in determining their biological functions. For instance, lncRNAs are…
Normalized relational databases are a common method for storing data, but pulling out usable denormalized data for consumption generally requires either direct access to the source data or creation of an appropriate view or table by a…
Microservices architectures are an integral part of modern software development. Their adoption brings significant changes to database management. Instead of relying on a single database, a microservices architecture is typically composed…
RNA secondary structure prediction and classification are two important problems in the field of RNA biology. Here, we propose a new permutation based approach to create logical non-disjoint clusters of different secondary structures of a…