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This is an empirical study to investigate the impact of scanner effects when using machine learning on multi-site neuroimaging data. We utilize structural T1-weighted brain MRI obtained from two different studies, Cam-CAN and UK Biobank.…

Image and Video Processing · Electrical Eng. & Systems 2019-10-11 Ben Glocker , Robert Robinson , Daniel C. Castro , Qi Dou , Ender Konukoglu

The brain is a highly complex organ consisting of a myriad of subsystems that flexibly interact and adapt over time and context to enable perception, cognition, and behavior. Understanding the multi-scale nature of the brain, i.e., how…

Neurons and Cognition · Quantitative Biology 2025-01-17 Adam S. Charles

Optical neuroimaging is a vital tool for understanding the brain structure and the connection between regions and nuclei. However, the image noise introduced in the sample preparation and the imaging system hinders the extraction of the…

Image and Video Processing · Electrical Eng. & Systems 2021-09-23 Tianfang Zhu , Yue Guan , Anan Li

Rapid advances in image processing capabilities have been seen across many domains, fostered by the application of machine learning algorithms to "big-data". However, within the realm of medical image analysis, advances have been curtailed,…

Computer Vision and Pattern Recognition · Computer Science 2019-09-05 Silas Ørting , Andrew Doyle , Arno van Hilten , Matthias Hirth , Oana Inel , Christopher R. Madan , Panagiotis Mavridis , Helen Spiers , Veronika Cheplygina

Normative modelling is an increasingly common statistical technique in neuroimaging that estimates population-level benchmarks in brain structure. It enables the quantification of individual deviations from expected distributions whilst…

Neurons and Cognition · Quantitative Biology 2025-10-21 Nida Alyas , Jonathan Horsley , Bethany Little , Peter N. Taylor , Yujiang Wang , Karoline Leiberg

The combination of deep learning image analysis methods and large-scale imaging datasets offers many opportunities to imaging neuroscience and epidemiology. However, despite the success of deep learning when applied to many neuroimaging…

Image and Video Processing · Electrical Eng. & Systems 2021-07-14 Nicola K Dinsdale , Emma Bluemke , Vaanathi Sundaresan , Mark Jenkinson , Stephen Smith , Ana IL Namburete

In psychiatry, we often speak of constructing "models." Here we try to make sense of what such a claim might mean, starting with the most fundamental question: "What is (and isn't) a model?". We then discuss, in a concrete measurable sense,…

Neurons and Cognition · Quantitative Biology 2020-04-15 LR Mujica-Parodi , HH Strey

Over the last ten years, developments in whole-brain microscopy now allow for high-resolution imaging of intact brains of small rodents such as mice. These complex images contain a wealth of information, but many neuroscience laboratories…

Neurons and Cognition · Quantitative Biology 2021-02-24 Adam L Tyson , Troy W Margrie

Random-effects meta-analyses are very commonly used in medical statistics. Recent methodological developments include multivariate (multiple outcomes) and network (multiple treatments) meta-analysis. Here we provide a new model and…

Methodology · Statistics 2017-08-16 Dan Jackson , Sylwia Bujkiewicz , Martin Law , Richard D Riley , Ian White

MemComputing is a new model of computation that exploits the non-equilibrium property-we call 'memory'-of any physical system to respond to external perturbations by keeping track of how it has reacted at previous times. Its digital,…

Disordered Systems and Neural Networks · Physics 2025-12-05 Massimiliano Di Ventra

Even though novel imaging techniques have been successful in studying brain structure and function, the measured biological signals are often contaminated by multiple sources of noise, arising due to e.g. head movements of the individual…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Brice Ozenne , Martin Norgaard , Cyril Pernet , Melanie Ganz

Abundant accumulation of digital histopathological images has led to the increased demand for their analysis, such as computer-aided diagnosis using machine learning techniques. However, digital pathological images and related tasks have…

Computer Vision and Pattern Recognition · Computer Science 2018-02-23 Daisuke Komura , Shumpei Ishikawa

Our understanding of complex systems rests on our ability to characterise how they perform distributed computation and integrate information. Advances in information theory have introduced several quantities to describe complex information…

Information Theory · Computer Science 2026-04-13 Alberto Liardi , George Blackburne , Hardik Rajpal , Fernando E. Rosas , Pedro A. M. Mediano

Machine learning methods can be a valuable aid in the scientific process, but they need to face challenging settings where data come from inhomogeneous experimental conditions. Recent meta-learning methods have made significant progress in…

Machine Learning · Computer Science 2024-03-21 Matthieu Blanke , Marc Lelarge

Intracranial recordings in epilepsy patients are increasingly utilized to gain insight into the electrophysiological mechanisms of human cognition. There are currently several practical limitations to conducting research with these…

Neurons and Cognition · Quantitative Biology 2021-06-23 Omer E Ashmaig , Liberty S Hamilton , Pradeep Modur , Robert J Buchanan , Alison R Preston , Andrew J Watrous

Statistical modeling of data sets by neural-network techniques is offered as an alternative to traditional semiempirical approaches to global modeling of nuclear properties. New results are presented to support the position that such novel…

Nuclear Theory · Physics 2017-08-23 J. W. Clark , E. Mavrommatis , S. Athanassopoulos , A. Dakos , K. Gernoth

Successful analytics solutions that provide valuable insights often hinge on the connection of various data sources. While it is often feasible to generate larger data pools within organizations, the application of analytics within…

Machine Learning · Computer Science 2023-03-29 Robin Hirt , Niklas Kühl , Dominik Martin , Gerhard Satzger

The science of solving clinical problems by analyzing images generated in clinical practice is known as medical image analysis. The aim is to extract information in an effective and efficient manner for improved clinical diagnosis. The…

Computer Vision and Pattern Recognition · Computer Science 2019-05-22 Syed Muhammad Anwar , Muhammad Majid , Adnan Qayyum , Muhammad Awais , Majdi Alnowami , Muhammad Khurram Khan

Metainformation is a common companion to biomedical images. However, this potentially powerful additional source of signal from image acquisition has had limited use in deep learning methods, for semantic segmentation in particular. Here,…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Iaroslav Plutenko , Mikhail Papkov , Kaupo Palo , Leopold Parts , Dmytro Fishman

Mutual Information (MI) is a fundamental metric for quantifying dependency between two random variables. When we can access only the samples, but not the underlying distribution functions, we can evaluate MI using sample-based estimators.…

Machine Learning · Statistics 2024-10-16 Kyungeun Lee , Wonjong Rhee