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- Modeling Human cardiovascular system is always an important issue. One of the most effective methods is using lumped model to reach to a complete model of human cardiovascular system. Such modeling with advanced considerations is used in…

Patient-specific computational models of the heart are powerful tools for cardiovascular research and medicine, with demonstrated applications in treatment planning, device evaluation, and surgical decision-making. Yet constructing such…

Medical Physics · Physics 2026-04-21 Aaron L. Brown , Ju Liu , Daniel B. Ennis , Alison L. Marsden

Consider briefly the equations of fluid dynamics-they describe the enormous wealth of detail in all the interacting physical elements of a fluid flow-whereas in applications we want to deal with a description of just that which is…

chao-dyn · Physics 2016-08-31 A. J. Roberts

Background and Objective: The role of red blood cell dynamics is emphasised in certain cardiovascular diseases, and thus needs to be closely studied. A multiphase model of blood flow allows the resolution of locally varying density of red…

Fluid Dynamics · Physics 2021-10-07 Konstantinos G. Lyras , Jack Lee

When very small particles are suspended in a fluid in motion, they tend to follow the flow. How such tracer particles are mixed, transported, and dispersed by turbulent flow has been successfully described by statistical models. Heavy…

Fluid Dynamics · Physics 2023-12-21 J. Bec , K. Gustavsson , B. Mehlig

A mathematical model of atherosclerosis of a blood vessel is advanced with regard for the entry of low-density lipoproteins (LDLs) into blood. For the first time, the influence of cytokines on the inflammation of a blood vessel at the…

Biological Physics · Physics 2025-03-25 V. I. Grytsay

Local hemodynamic forces play an important role in determining the functional significance of coronary arterial stenosis and understanding the mechanism of coronary disease progression. Computational fluid dynamics (CFD) have been widely…

Computer Vision and Pattern Recognition · Computer Science 2023-05-31 Ziyu Ni , Linda Wei , Lijian Xu , Simon Yu , Qing Xia , Hongsheng Li , Shaoting Zhang

The red blood cell (RBC) membrane is composed of a lipid bilayer and a cytoskeleton interconnected by protein junction complexes, allowing for potential sliding between the lipid bilayer and the cytoskeleton. Despite this biological…

Fluid Dynamics · Physics 2024-01-23 V. Puthumana , P. G. Chen , M. Leonetti , R. Lasserre , M. Jaeger

Methods of Computational Fluid Dynamics are applied to simulate pulsatile blood flow in human vessels and in the aortic arch. The non-Newtonian behaviour of the human blood is investigated in simple vessels of actual size. A detailed…

Computational Physics · Physics 2008-02-19 Renat A. Sultanov , Dennis Guster , Brent Engelbrekt , Richard Blankenbecler

In this paper, we present a mathematical and numerical model for blood solidification and its rupture in stenosed arteries. The interaction between the blood flow and an existing stenosis in the arterial wall is modeled as a three…

Numerical Analysis · Mathematics 2020-05-15 Fatima Abbas , Ayman Mourad

Accurate classification of blood cells plays a key role in improving automated blood analysis for both medical and veterinary applications. This work presents a two-stage deep clustering method for classifying blood cells from…

Quantitative Methods · Quantitative Biology 2025-09-25 Mihaela Macarie-Ancau , Adrian Groza

The plasma membrane of human red blood cells consists of a lipid bilayer attached to a regular network of underlying cytoskeletal polymers. We model this system at a dynamic coarse-grained level, treating the bilayer as an elastic sheet and…

Subcellular Processes · Quantitative Biology 2009-11-13 Rui Zhang , Frank L. H. Brown

In this work, we investigate how concepts from medical flow visualization can be applied to enhance stroke prevention diagnostics. Our focus lies on carotid stenoses, i.e., local narrowings of the major brain-supplying arteries, which are a…

Medical Physics · Physics 2021-04-07 Pepe Eulzer , Monique Meuschke , Carsten Klingner , Kai Lawonn

Blood flow in arterial systems can be described by the three-dimensional Navier-Stokes equations within a time-dependent spatial domain that accounts for the elasticity of the arterial walls. In this article blood is treated as an…

Numerical Analysis · Mathematics 2018-08-14 Francesco Fambri , Michael Dumbser , Vincenzo Casulli

The emergence of computational fluid dynamics (CFD) enabled the simulation of intricate transport processes, including flow in physiological structures, such as blood vessels. While these so-called hemodynamic simulations offer…

We analyze left atrium haemodynamics, highlighting differences among healthy individuals and patients affected by atrial fibrillation. The computational study is based on patient-specific geometries of the left atria to simulate blood flow…

Fluid Dynamics · Physics 2022-10-06 Mattia Corti , Alberto Zingaro , Luca Dede' , Alfio Maria Quarteroni

Strokes are still one of the leading causes for death after heart diseases and cancer in all over the world. Most strokes happen because an artery that carries blood uphill from the heart to the head gets clogged. Most of the time, as with…

Tissues and Organs · Quantitative Biology 2020-02-03 Nurullah Arslan , Kazim Besirli , Gurcan Comert , Omer F Beyca

Past approaches for statistical shape analysis of objects have focused mainly on objects within the same topological classes, e.g., scalar functions, Euclidean curves, or surfaces, etc. For objects that differ in more complex ways, the…

Computer Vision and Pattern Recognition · Computer Science 2020-05-18 Xiaoyang Guo , Anuj Srivastava

A new two-dimensional model for blood flows in arteries with arbitrary cross sections is derived. The model consists of a system of balance laws for conservation of mass and balance of momentum in the axial and angular directions. The…

Numerical Analysis · Mathematics 2021-08-23 Cesar Alberto Rosales-Alcantar , Gerardo Hernandez-Duenas

We performed numerical simulations of blood flow in arteries with a variable stiffness and cross-section at rest using a finite volume method coupled with a hydrostatic reconstruction of the variables at the interface of each mesh cell. The…

Numerical Analysis · Mathematics 2015-09-15 Olivier Delestre , Arthur Ghigo , Jose-Maria Fullana , Pierre-Yves Lagrée