Related papers: Developing a computational model of blood platelet…
The influence of blood rheology on hemodynamic parameters is investigated using Computational Fluid Dynamics on blood flow through the human carotid artery. We performed three-dimensional modeling and simulation to study blood flow through…
Detection and monitoring of patients with pulmonary hypertension, defined as mean blood pressure in the main pulmonary artery above 25 mmHg, requires a combination of imaging and hemodynamic measurements. This study demonstrates how to…
The biomechanical properties of blood clots, which are dictated by their compositions and micro-structures, play a critical role in determining their fates, occlusion, persistency, or embolization in the human circulatory system. While…
An accurate prediction of the translational and rotational motion of particles suspended in a fluid is only possible if a complete set of correlations for the force coefficients of fluid-particle interaction is known. The present study is…
Various properties of fluids consisting of platelike particles differ from the corresponding ones of fluids consisting of spherical particles because interactions between platelets depend on their mutual orientations. One of the main issues…
The dynamical mechanical analysis of blood generally uses models inspired by conventional flows, assuming scale-independent homogeneous flows and without considering fluid-surface boundary interactions. The present experimental study…
The appearance of detached recirculation regions in wakes with base bleed determines the aerodynamic properties of many natural organisms and technological applications. In this work we introduce an analytical model which captures certain…
Arrhythmias are potentially fatal disruptions to the normal heart rhythm, but their underlying dynamics is still poorly understood. Theoretical modeling is an important tool to fill this gap. Typical studies often employ detailed…
There is currently limited understanding of the role played by haemodynamic forces on the processes governing vascular development. One of many obstacles to be overcome is being able to measure those forces, at the required resolution…
Purpose: Hemolysis is a key issue in the design of blood-handling medical devices. Computational prediction of this phenomenon is challenging due to the complex multiscale nature of blood. As a result, conventional approaches often fail to…
To address the issue of computational efficiency related to the modelling of blood flow in complex networks, we derive a family of nonlinear lumped-parameter models for blood flow in compliant vessels departing from a well-established…
Advances in computational science offer a principled pipeline for predictive modeling of cardiovascular flows and aspire to provide a valuable tool for monitoring, diagnostics and surgical planning. Such models can be nowadays deployed on…
Cardiovascular diseases (CVDs) are the leading causes of mortality worldwide. The contraction and relaxation of left ventricle (LV) is the main driving force of blood circulation. Altered LV hemodynamics is believed to be associated with…
The availability of digital twins for the cardiovascular system will enable insightful computational tools both for research and clinical practice. This, however, demands robust and well defined models and methods for the different steps…
Biomolecular condensates play a central role in the spatial organization of living matter. Their formation is now well understood as a form of liquid-liquid phase separation that occurs very far from equilibrium. For instance, they can be…
Driven or active suspensions can display fascinating collective behavior, where coherent motions or structures arise on a scale much larger than that of the constituent particles. Here, we report experiments and numerical simulations…
Ischemia leading to heart attacks and strokes is the major cause of deaths in the world. Whether an occlusion occurs or not, depends on the ability of a growing thrombus to resist forces exerted on its structure. This manuscript provides…
We propose an integrated electromechanical model of the human heart, with focus on the left ventricle, wherein biophysically detailed models describe the different physical phenomena concurring to the cardiac function. We model the…
Mathematical models that accurately predict the mechanical behavior of blood can contribute to the development of biomedical devices and medications which are relevant in clinical applications. The models existing in the literature are…
In this paper we will address the problem of developing mathematical models for the numerical simulation of the human circulatory system. In particular, we will focus our attention on the problem of haemodynamics in large human arteries.