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When an infectious disease propagates throughout society, the incidence function may rise at first due to an increase in pathogenicity and then decrease due to inhibitory effects until it reaches saturation. Effective vaccination and…

Dynamical Systems · Mathematics 2023-07-11 Sushil Pathak , G. Shirisha , K. Venkata Ratnam

This paper focuses on and analyzes realistic SIR models that take stochasticity into account. The proposed systems are applicable to most incidence rates that are used in the literature including the bilinear incidence rate, the…

Probability · Mathematics 2024-07-10 Nguyen Du , Alexandru Hening , Nhu Nguyen , George Yin

We study an SEIQR (Susceptible-Exposed-Infectious-Quarantined-Recovered) model for an infectious disease, with time delays for latency and an asymptomatic phase. For fast pandemics where nobody has prior immunity and everyone has immunity…

Populations and Evolution · Quantitative Biology 2020-04-09 C. P. Vyasarayani , Anindya Chatterjee

We consider the SEIRS epidemiology model with such features of the COVID-19 outbreak as: abundance of unidentified infected individuals, limited time of immunity and a possibility of vaccination. The control of the pandemic dynamics is…

Populations and Evolution · Quantitative Biology 2026-03-31 J. Ilnytskyi , T. Patsahan

This paper studies the dynamics of a network-based SIRS epidemic model with vaccination and a nonmonotone incidence rate. This type of nonlinear incidence can be used to describe the psychological or inhibitory effect from the behavioral…

Populations and Evolution · Quantitative Biology 2018-11-14 Lijun Liu , Xiaodan Wei , Naimin Zhang

We analyze the identifiability and observability of the well-known SIR epidemic model with an additional compartment Q of the sub-population of infected individuals that are placed in quarantine (SIQR model), considering that the flow of…

Dynamical Systems · Mathematics 2021-03-09 Frédéric Hamelin , Abderrahman Iggidr , Alain Rapaport , Gauthier Sallet , Max Souza

In contrast to the common assumption in epidemic models that the rate of infection between individuals is constant, in reality, an individual's viral load determines their infectiousness. We compare the average and individual reproductive…

Populations and Evolution · Quantitative Biology 2021-12-07 Nicholas Landry

We propose a compartmental model for a disease with temporary immunity and secondary infections. From our assumptions on the parameters involved in the model, the system naturally evolves in three time scales. We characterize the equilibria…

Dynamical Systems · Mathematics 2024-04-10 Panagiotis Kaklamanos , Andrea Pugliese , Mattia Sensi , Sara Sottile

We study an infection-age structured epidemic model in which both the infectivity and the rate of loss of immunity depend on the time-since-infection. The model can be equivalently viewed as a nonlinear renewal equation for the incidence of…

Dynamical Systems · Mathematics 2025-11-13 Francesca Scarabel , Harry Coldwell , Tyler Cassidy

Stochastic discrete-time SIS and SIR models of endemic diseases are introduced and analyzed. For the deterministic, mean-field model, the basic reproductive number $R_0$ determines their global dynamics. If $R_0\le 1$, then the frequency of…

Populations and Evolution · Quantitative Biology 2020-05-19 Sebastian J. Schreiber , Shuo Huang , Jifa Jiang , Hao Wang

This paper studies the spread dynamics of a stochastic SIRS epidemic model with nonlinear incidence and varying population size, which is formulated as a piecewise deterministic Markov process. A threshold dynamic determined by the basic…

Dynamical Systems · Mathematics 2017-10-26 Dan Li , Shengqiang Liu , Jing'an Cui

The Susceptible-Infected-Recovered (SIR) model is the cornerstone of epidemiological models. However, this specification depends on two parameters only, which implies a lack of flexibility and the difficulty to replicate the volatile…

Populations and Evolution · Quantitative Biology 2020-11-17 Christian Gourieroux , Yang Lu

This paper examines a susceptible-infected-susceptible (SIS) epidemic reaction-diffusion model with no-flux boundary conditions and constant total population. The infection mechanism in the model is described by a nonlinear term of the form…

Analysis of PDEs · Mathematics 2024-12-20 Rui Peng , Rachidi B Salako , Yixiang Wu

This paper deals with a new epidemiological model of SIRS with stochastic perturbations. The primary objective is to establish the existence of a unique non-negative nonlocal solution. Using the basic reproduction number $\mathscr{R}_0$…

Dynamical Systems · Mathematics 2025-03-10 Achraf Zinihi , Moulay Rchid Sidi Ammi , Matthias Ehrhardt

For centuries isolation has been the main control strategy of unforeseen epidemic outbreaks. When implemented in full and without delay, isolation is very effective. However, flawless implementation is seldom feasible in practice. We…

Populations and Evolution · Quantitative Biology 2019-01-23 Lai-Sang Young , Stefan Ruschel , Serhiy Yanchuk , Tiago Pereira

The SIR model is a three-compartment model of the time development of an epidemic. After normalizing the dependent variables, the model is a system of two non-linear differential equations for the susceptible proportion $S$ and the infected…

Dynamical Systems · Mathematics 2021-04-27 William G. Faris

This paper considers a susceptible-infected-susceptible (SIS) epidemic reaction-diffusion model with no-flux boundary conditions and varying total population. The interaction of the susceptible and infected people is describe by the…

Analysis of PDEs · Mathematics 2024-12-13 Rui Peng , Rachidi B. Salako , Yixiang Wu

The infection dynamics of a population under stationary isolation conditions is modeled. It is underlined that the stationary character of the isolation measures can be expected to imply that an effective SIR model with constant parameters…

Populations and Evolution · Quantitative Biology 2021-10-19 Alejandro Cabo Montes de Oca , Nana Geraldine Cabo Bizet

In this work we analyze mathematically the consequences and effectiveness of strategies to control an epidemic in the framework of classical SEIR models with multiple parallel infectious stages. We define the mathematical concept of a…

Dynamical Systems · Mathematics 2023-08-17 Annibal Figueiredo , Tarcısio Marciano da Rocha Filho

A significant proportion of the infections driving the current {SARS-CoV-2} pandemic are transmitted asymptomatically. Here we introduce and study a simple epidemic model with separate compartments comprising asymptomatic and symptomatic…

Populations and Evolution · Quantitative Biology 2022-10-12 Maurice Görtz , Joachim Krug