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The flatfish is a major farmed species consumed globally in large quantities. However, due to the densely populated farming environment, flatfish are susceptible to lesions and diseases, making early lesion detection crucial. Traditionally,…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Seo-Bin Hwang , Han-Young Kim , Chae-Yeon Heo , Hie-Yong Jeong , Sung-Ju Jung , Yeong-Jun Cho

Chromosome analysis is a fundamental step in the diagnosis of genetic diseases, but the manual karyotyping workflow is time-consuming and heavily dependent on expert specialists, often requiring several days per patient. Although Deep…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Jorge L. A. Lima , Filipe R. Cordeiro

We present cytometric classification of live healthy and cancer cells by using the spatial morphological and textural information found in the label-free quantitative phase images of the cells. We compare both healthy cells to primary tumor…

Quantitative Methods · Quantitative Biology 2020-01-23 Darina Roitshtain , Lauren Wolbromsky , Evgeny Bal , Hayit Greenspan , Lisa L. Satterwhite , Natan T. Shaked

A novel and fast semi-automatic method for segmentation, locating and counting blood cells in an image is proposed. In this method, thresholding is used to separate the nucleus from the other parts. We also use Hough transform for circles…

Image and Video Processing · Electrical Eng. & Systems 2020-04-21 Hamed Sadeghi , Shahram Shirani , David W. Capson

As recent text-conditioned diffusion models have enabled the generation of high-quality images, concerns over their potential misuse have also grown. This issue is critical in the medical domain, where text-conditioned generated medical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Chanyoung Kim , Dayun Ju , Jinyeong Kim , Woojung Han , Roberto Alcover-Couso , Seong Jae Hwang

Phenotype variations define heterogeneity of biological and molecular systems, which play a crucial role in several mechanisms. Heterogeneity has been demonstrated in tumor cells. Here, samples from blood of patients affected from colon…

Biological Physics · Physics 2015-11-09 Giuseppina Simone

State-of-the-art image segmentation algorithms generally consist of at least two successive and distinct computations: a boundary detection process that uses local image information to classify image locations as boundaries between objects,…

Computer Vision and Pattern Recognition · Computer Science 2016-11-03 Michał Januszewski , Jeremy Maitin-Shepard , Peter Li , Jörgen Kornfeld , Winfried Denk , Viren Jain

Phenotype segmentation is pivotal in analysing visual features of living organisms, enhancing our understanding of their characteristics. In the context of oysters, meat quality assessment is paramount, focusing on shell, meat, gonad, and…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Wenli Yang , Yanyu Chen , Andrew Trotter , Byeong Kang

Random splitting of datasets in image segmentation often leads to unrepresentative test sets, resulting in biased evaluations and poor model generalization. While stratified sampling has proven effective for addressing label distribution…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Naga Venkata Sai Jitin Jami , Thomas Altstidl , Jonas Mueller , Jindong Li , Dario Zanca , Bjoern Eskofier , Heike Leutheuser

To assist researchers to identify Environmental Microorganisms (EMs) effectively, a Multiscale CNN-CRF (MSCC) framework for the EM image segmentation is proposed in this paper. There are two parts in this framework: The first is a novel…

Computer Vision and Pattern Recognition · Computer Science 2021-02-25 Jinghua Zhang , Chen Li , Frank Kulwa , Xin Zhao , Changhao Sun , Zihan Li , Tao Jiang , Hong Li , Shouliang Qi

Detecting and segmenting individual cells from microscopy images is critical to various life science applications. Traditional cell segmentation tools are often ill-suited for applications in brightfield microscopy due to poor contrast and…

Image and Video Processing · Electrical Eng. & Systems 2020-05-20 Rituparna Sarkar , Suvadip Mukherjee , Elisabeth Labruyère , Jean-Christophe Olivo-Marin

Single cell segmentation is critical and challenging in live cell imaging data analysis. Traditional image processing methods and tools require time-consuming and labor-intensive efforts of manually fine-tuning parameters. Slight variations…

Quantitative Methods · Quantitative Biology 2019-04-24 Weikang Wang , David A. Taft , Yi-Jiun Chen , Jingyu Zhang , Callen T. Wallace , Min Xu , Simon C. Watkins , Jianhua Xing

A general framework of spatio-spectral segmentation for multi-spectral images is introduced in this paper. The method is based on classification-driven stochastic watershed (WS) by Monte Carlo simulations, and it gives more regular and…

Computer Vision and Pattern Recognition · Computer Science 2016-02-10 Guillaume Noyel , Jesus Angulo , Dominique Jeulin

The current standard for detecting human epidermal growth factor receptor 2 (HER2) status in breast cancer patients relies on HER2 amplification, identified through fluorescence in situ hybridization (FISH) or immunohistochemistry (IHC).…

Image and Video Processing · Electrical Eng. & Systems 2024-09-27 Ardhendu Sekhar , Vrinda Goel , Garima Jain , Abhijeet Patil , Ravi Kant Gupta , Tripti Bameta , Swapnil Rane , Amit Sethi

Medical image colorization can greatly enhance the interpretability of the underlying imaging modality and provide insights into human anatomy. The objective of medical image colorization is to transfer a diverse spectrum of colors…

Image and Video Processing · Electrical Eng. & Systems 2024-12-17 Mayuri Mathur , Anav Chaudhary , Saurabh Kumar Gupta , Ojaswa Sharma

We present a weakly supervised deep learning method to perform instance segmentation of cells present in microscopy images. Annotation of biomedical images in the lab can be scarce, incomplete, and inaccurate. This is of concern when…

Computer Vision and Pattern Recognition · Computer Science 2019-08-28 Fidel A. Guerrero-Peña , Pedro D. Marrero Fernandez , Tsang Ing Ren , Alexandre Cunha

Automated chromosome instance segmentation from metaphase cell microscopic images is critical for the diagnosis of chromosomal disorders (i.e., karyotype analysis). However, it is still a challenging task due to lacking of densely annotated…

Computer Vision and Pattern Recognition · Computer Science 2023-04-26 Dan You , Pengcheng Xia , Qiuzhu Chen , Minghui Wu , Suncheng Xiang , Jun Wang

We propose a new method for cancer subtype classification from histopathological images, which can automatically detect tumor-specific features in a given whole slide image (WSI). The cancer subtype should be classified by referring to a…

Computer Vision and Pattern Recognition · Computer Science 2020-04-03 Noriaki Hashimoto , Daisuke Fukushima , Ryoichi Koga , Yusuke Takagi , Kaho Ko , Kei Kohno , Masato Nakaguro , Shigeo Nakamura , Hidekata Hontani , Ichiro Takeuchi

In the field of image analysis, segmentation is one of the most important preprocessing steps. One way to achieve segmentation is by mean of threshold selection, where each pixel that belongs to a determined class islabeled according to the…

Computer Vision and Pattern Recognition · Computer Science 2014-05-30 Valentín Osuna-Enciso , Erik Cuevas , Humberto Sossa

We describe a novel cancer diagnostic method based on plasma denaturation profiles obtained by a non-conventional use of Differential Scanning Fluorimetry. We show that 84 glioma patients and 63 healthy controls can be automatically…

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