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Modern biomedical image analysis using deep learning often encounters the challenge of limited annotated data. To overcome this issue, deep generative models can be employed to synthesize realistic biomedical images. In this regard, we…

Image and Video Processing · Electrical Eng. & Systems 2026-02-23 Yuli Wu , Weidong He , Dennis Eschweiler , Ningxin Dou , Zixin Fan , Shengli Mi , Peter Walter , Johannes Stegmaier

Optical coherence tomography (OCT) is widely used for diagnosing and monitoring retinal diseases, such as age-related macular degeneration (AMD). The segmentation of biomarkers such as layers and lesions is essential for patient diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Botond Fazekas , Guilherme Aresta , Philipp Seeböck , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunović

Optical coherence tomography (OCT) can perform non-invasive high-resolution three-dimensional (3D) imaging and has been widely used in biomedical fields, while it is inevitably affected by coherence speckle noise which degrades OCT imaging…

Optics · Physics 2025-06-30 Renxiong Wu , Fei Zheng , Meixuan Li , Shaoyan Huang , Xin Ge , Linbo Liu , Yong Liu , Guangming Ni

Optical coherence tomography (OCT) is a noninvasive imaging modality which can be used to obtain depth images of the retina. The changing layer thicknesses can thus be quantified by analyzing these OCT images, moreover these changes have…

Computer Vision and Pattern Recognition · Computer Science 2018-03-15 Yufan He , Aaron Carass , Bruno M. Jedynak , Sharon D. Solomon , Shiv Saidha , Peter A. Calabresi , Jerry L. Prince

Retinal optical coherence tomography (OCT) and OCT angiography (OCTA) suffer from the degeneration of image quality due to speckle noise and bulk-motion noise, respectively. Because the cross-sectional retina has distinct features in OCT…

Image and Video Processing · Electrical Eng. & Systems 2020-02-19 Jianlong Yang , Yan Hu , Liyang Fang , Jun Cheng , Jiang Liu

Optical coherence tomography (OCT) is an important interferometric diagnostic technique which provides cross-sectional views of the subsurface microstructure of biological tissues. However, the imaging quality of high-speed OCT is limited…

Computer Vision and Pattern Recognition · Computer Science 2015-03-13 Liheng Bian , Jinli Suo , Feng Chen , Qionghai Dai

Optical Coherence Tomography (OCT) has become an indispensable tool for investigating mesoscopic features in soft matter and fluid mechanics. Its ability to provide high-resolution, non-invasive measurements in both spatial and temporal…

For accurate glaucoma diagnosis and monitoring, reliable retinal layer segmentation in OCT images is essential. However, existing 2D segmentation methods often suffer from slice-to-slice inconsistencies due to the lack of contextual…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Hyunwoo Kim , Heesuk Kim , Wungrak Choi , Jae-Sang Hyun

A new formulation of lateral imaging process of point-scanning optical coherence tomography (OCT) and a new differential contrast method designed by using this formulation are presented. The formulation is based on a mathematical sample…

Segmentation of indicated targets aids in the precise analysis of optical coherence tomography angiography (OCTA) samples. Existing segmentation methods typically perform on 2D projection targets, making it challenging to capture the…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Xinrun Chen , Chengliang Wang , Haojian Ning , Mengzhan Zhang , Mei Shen , Shiying Li

The automatic detection and localization of anatomical features in retinal imaging data are relevant for many aspects. In this work, we follow a data-centric approach to optimize classifier training for optic nerve head detection and…

Image and Video Processing · Electrical Eng. & Systems 2022-08-09 Thomas Schlegl , Heiko Stino , Michael Niederleithner , Andreas Pollreisz , Ursula Schmidt-Erfurth , Wolfgang Drexler , Rainer A. Leitgeb , Tilman Schmoll

Optical Coherence Tomography (OCT) enables the acquisition of high-resolution, three-dimensional fingerprint data, capturing rich subsurface structures for robust biometric recognition. However, the high cost and time-consuming nature of…

Computer Vision and Pattern Recognition · Computer Science 2025-09-01 Qingran Miao , Haixia Wang , Haohao Sun , Yilong Zhang

Optical coherence tomography (OCT) uses low-coherence reflectometry to obtain cross-sectional images of inhomogeneous media, such as biological tissue. OCT is particularly useful in the biomedical ea, since the imaging can be performed…

Medical Physics · Physics 2018-03-01 Takahisa Mitsui , Kenichiro Aoki

Optical coherence tomography (OCT) is one of the non-invasive and easy-to-acquire biomarkers (the thickness of the retinal layers, which is detectable within OCT scans) being investigated to diagnose Alzheimer's disease (AD). This work aims…

Image and Video Processing · Electrical Eng. & Systems 2022-06-14 Paria Jeihouni , Omid Dehzangi , Annahita Amireskandari , Ali Dabouei , Ali Rezai , Nasser M. Nasrabadi

Retinal Optical Coherence Tomography (OCT) segmentation is essential for diagnosing pathology. Traditional methods focus on either spatial or spectral domains, overlooking their combined dependencies. We propose a triple-encoder network…

Image and Video Processing · Electrical Eng. & Systems 2025-11-26 Kristin Qi , Xinhan Di

High anisotropy in volumetric medical images can lead to the inconsistent quantification of anatomical and pathological structures. Particularly in optical coherence tomography (OCT), slice spacing can substantially vary across and within…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Coen de Vente , Mohammad Mohaiminul Islam , Philippe Valmaggia , Carel Hoyng , Adnan Tufail , Clara I. Sánchez

Tracking and localizing objects is a central problem in computer-assisted surgery. Optical coherence tomography (OCT) can be employed as an optical tracking system, due to its high spatial and temporal resolution. Recently, 3D convolutional…

Image and Video Processing · Electrical Eng. & Systems 2020-07-03 Marcel Bengs , Nils Gessert , Alexander Schlaefer

Optical coherence tomography (OCT) is a prevalent imaging technique for retina. However, it is affected by multiplicative speckle noise that can degrade the visibility of essential anatomical structures, including blood vessels and tissue…

Image and Video Processing · Electrical Eng. & Systems 2021-07-12 Dewei Hu , Joseph D. Malone , Yigit Atay , Yuankai K. Tao , Ipek Oguz

Advances in optical coherence tomography (OCT) have enabled noninvasive imaging of substructures of the human retina with high spatial resolution. OCT examinations are now a standard procedure in clinics and an integral part of ophthalmic…

Human-Computer Interaction · Computer Science 2022-12-22 Martin Röhlig , Oliver Stachs , Heidrun Schumann

Objective: To achieve accurate 3-D reconstruction and quantitative analysis of human retinal vasculature from a single optical coherence tomography angiography (OCTA) scan. Methods: We introduce Freqformer, a novel Transformer-based model…

Image and Video Processing · Electrical Eng. & Systems 2025-09-30 Lingyun Wang , Bingjie Wang , Jay Chhablani , Jose Alain Sahel , Shaohua Pi