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Optical coherence tomography (OCT) based measurements of retinal layer thickness, such as the retinal nerve fibre layer (RNFL) and the ganglion cell with inner plexiform layer (GCIPL) are commonly used for the diagnosis and monitoring of…

Computer Vision and Pattern Recognition · Computer Science 2019-10-25 Stefan Maetschke , Bhavna Antony , Hiroshi Ishikawa , Gadi Wollstein , Joel S. Schuman , Rahil Garnavi

Optical coherence tomography (OCT) and confocal microscopy are pivotal in retinal imaging, each presenting unique benefits and limitations. In-vivo OCT offers rapid, non-invasive imaging but can be hampered by clarity issues and motion…

Image and Video Processing · Electrical Eng. & Systems 2024-10-30 Xin Tian , Nantheera Anantrasirichai , Lindsay Nicholson , Alin Achim

Speckle is an intrinsic pattern in optical coherence tomography (OCT) that obscures fine image features and degrades effective resolution. In this study, we propose a numerical speckle reduction method based on the dispersed scatterer model…

We customize an end-to-end image compression framework for retina OCT images based on deep convolutional neural networks (CNNs). The customized compression scheme consists of three parts: data Preprocessing, compression CNNs, and…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Pengfei Guo , Dawei Li , Xingde Li

Medical image analysis using deep learning has recently been prevalent, showing great performance for various downstream tasks including medical image segmentation and its sibling, volumetric image segmentation. Particularly, a typical…

Computer Vision and Pattern Recognition · Computer Science 2024-03-01 Ngoc-Vuong Ho , Tan Nguyen , Gia-Han Diep , Ngan Le , Binh-Son Hua

Retinal Vessel Segmentation is important for the diagnosis of various diseases. The research on retinal vessel segmentation focuses mainly on the improvement of the segmentation model which is usually based on U-Net architecture. In our…

Image and Video Processing · Electrical Eng. & Systems 2021-06-01 Enes Sadi Uysal , M. Şafak Bilici , B. Selin Zaza , M. Yiğit Özgenç , Onur Boyar

Registration of longitudinal optical coherence tomography (OCT) images assists disease monitoring and is essential in image fusion applications. Mouse retinal OCT images are often collected for longitudinal study of eye disease models such…

Computer Vision and Pattern Recognition · Computer Science 2024-02-13 Xin Tian , Nantheera Anantrasirichai , Lindsay Nicholson , Alin Achim

For 3D medical image (e.g. CT and MRI) segmentation, the difficulty of segmenting each slice in a clinical case varies greatly. Previous research on volumetric medical image segmentation in a slice-by-slice manner conventionally use the…

Image and Video Processing · Electrical Eng. & Systems 2022-07-12 Wenxuan Wang , Chen Chen , Jing Wang , Sen Zha , Yan Zhang , Jiangyun Li

Advances in fluorescence microscopy enable acquisition of 3D image volumes with better image quality and deeper penetration into tissue. Segmentation is a required step to characterize and analyze biological structures in the images and…

Computer Vision and Pattern Recognition · Computer Science 2019-04-16 Chichen Fu , Soonam Lee , David Joon Ho , Shuo Han , Paul Salama , Kenneth W. Dunn , Edward J. Delp

We present a novel method for characterizing the microstructure of a material from volumetric datasets such as 3D image data from computed tomography (CT). The method is based on a new statistical model for the distribution of voxel…

Materials Science · Physics 2021-01-06 Elise Otterlei Brenne , Vedrana Andersen Dahl , Peter Stanley Jørgensen

Retinal neovascularization (RNV) is a vision threatening development in diabetic retinopathy (DR). Vision loss associated with RNV is preventable with timely intervention, making RNV clinical screening and monitoring a priority. Optical…

Image and Video Processing · Electrical Eng. & Systems 2026-04-01 Jinyi Hao , Jie Wang , Liqin Gao , Tristan T. Hormel , Yukun Guo , An-Lun Wu , Christina J. Flaxel , Steven T. Bailey , Kotaro Tsuboi , Thomas S. Hwang , Yali Jia

Clinical measurement of a patient's axial eye length is emerging as a crucial approach to track progression and monitor management of myopia. However, the preferred method for such measurements is swept-source OCT, whose cost prohibits…

In this paper, we propose a framework that incorporates experts diagnostics and insights into the analysis of Optical Coherence Tomography (OCT) using multi-modal learning. To demonstrate the effectiveness of this approach, we create a…

Image and Video Processing · Electrical Eng. & Systems 2022-03-22 Y. Logan , K. Kokilepersaud , G. Kwon , G. AlRegib , C. Wykoff , H. Yu

In this work we propose a ResNet-based universal method for speckle reduction in optical coherence tomography (OCT) images. The proposed model contains 3 main modules: Convolution-BN-ReLU, Branch and Residual module. Unlike traditional…

Computer Vision and Pattern Recognition · Computer Science 2019-03-25 Cai Ning , Shi Fei , Hu Dianlin , Chen Yang

In the analysis of optical coherence tomography angiography (OCTA) images, the operation of segmenting specific targets is necessary. Existing methods typically train on supervised datasets with limited samples (approximately a few…

Computer Vision and Pattern Recognition · Computer Science 2023-09-22 Chengliang Wang , Xinrun Chen , Haojian Ning , Shiying Li

Aortic dissection is a serious pathology and requires an emergency management. It is characterized by one or more tears of the intimal wall of the normal blood duct of the aorta (true lumen); the blood under pressure then creates a second…

Image and Video Processing · Electrical Eng. & Systems 2025-07-08 Christophe Lohou , Bruno Miguel

Segmentation in 3D scans is playing an increasingly important role in current clinical practice supporting diagnosis, tissue quantification, or treatment planning. The current 3D approaches based on convolutional neural networks usually…

Computer Vision and Pattern Recognition · Computer Science 2019-03-12 Alexey Novikov , David Major , Maria Wimmer , Dimitrios Lenis , Katja Bühler

Transmission optical coherence tomography (OCT) enables analysis of biological specimens in vitro through detection of forward scattered light. Up to now, transmission OCT was considered as a technique that cannot directly retrieve…

Optics · Physics 2024-05-24 Wojciech Krauze , Martyna Mazur , Arkadiusz Kuś

The automatic segmentation of retinal layer structures enables clinically-relevant quantification and monitoring of eye disorders over time in OCT imaging. Eyes with late-stage diseases are particularly challenging to segment, as their…

Computer Vision and Pattern Recognition · Computer Science 2017-07-18 Stefanos Apostolopoulos , Sandro De Zanet , Carlos Ciller , Sebastian Wolf , Raphael Sznitman

The intensity levels allowed by safety standards (ANSI or ICNIRP) limit the amount of light that can be used in a clinical setting to image highly scattering or absorptive tissues with Optical Coherence Tomography (OCT). To achieve…

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