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Chaos control in Random Boolean networks is implemented by freezing part of the network to drive it from chaotic to ordered phase. However, controlled nodes are only viewed as passive blocks to prevent perturbation spread. This paper…

Cellular Automata and Lattice Gases · Physics 2015-05-20 Nan Jiang , Shijian Chen

We study the problem of computing a minimal subset of nodes of a given asynchronous Boolean network that need to be controlled to drive its dynamics from an initial steady state (or attractor) to a target steady state. Due to the phenomenon…

Systems and Control · Computer Science 2018-05-18 Soumya Paul , Cui Su , Jun Pang , Andrzej Mizera

Boolean networks have been used successfully in modeling biological networks and provide a good framework for theoretical analysis. However, the analysis of large networks is not trivial. In order to simplify the analysis of such networks,…

Molecular Networks · Quantitative Biology 2013-11-29 Alan Veliz-Cuba , Reinhard Laubenbacher , Boris Aguilar

The mutations of a complex systemic disease like cancer can be modeled as stuck-at faults in the Boolean system paradigm. For a class of multiple faults, the fault identification is exceptionally significant under the incomplete access of…

Systems and Control · Computer Science 2018-09-11 Anuj Deshpande , Ritwik Kumar Layek

Genetic regulatory networks control ontogeny. For fifty years Boolean networks have served as models of such systems, ranging from ensembles of random Boolean networks as models for generic properties of gene regulation to working dynamical…

Molecular Networks · Quantitative Biology 2019-02-04 Stefan Bornholdt , Stuart Kauffman

The problem of reliability of the dynamics in biological regulatory networks is studied in the framework of a generalized Boolean network model with continuous timing and noise. Using well-known artificial genetic networks such as the…

Molecular Networks · Quantitative Biology 2008-05-28 Stefan Braunewell , Stefan Bornholdt

The significant role of epigenetic mechanisms within natural systems has become increasingly clear. This paper uses a recently presented abstract, tunable Boolean genetic regulatory network model to explore aspects of epigenetics. It is…

Neural and Evolutionary Computing · Computer Science 2013-06-21 Larry Bull

Different Boolean networks may reveal similar dynamics although their definition differs, then preventing their distinction from the observations. This raises the question about the sufficiency of a particular Boolean network for properly…

Discrete Mathematics · Computer Science 2014-11-25 Franck Delaplace

Normalizing flows have emerged as an important family of deep neural networks for modelling complex probability distributions. In this note, we revisit their coupling and autoregressive transformation layers as probabilistic graphical…

Machine Learning · Computer Science 2020-06-05 Antoine Wehenkel , Gilles Louppe

Normalizing Flows are a promising new class of algorithms for unsupervised learning based on maximum likelihood optimization with change of variables. They offer to learn a factorized component representation for complex nonlinear data and,…

Machine Learning · Computer Science 2020-02-17 Reuben Feinman , Nikhil Parthasarathy

We consider collocated wireless sensor networks, where each node has a Boolean measurement and the goal is to compute a given Boolean function of these measurements. We first consider the worst case setting and study optimal block…

Information Theory · Computer Science 2011-05-09 Hemant Kowshik , P. R. Kumar

The co-evolution of network topology and dynamics is studied in an evolutionary Boolean network model that is a simple model of gene regulatory network. We find that a critical state emerges spontaneously resulting from interplay between…

Statistical Mechanics · Physics 2007-05-23 Min Liu , Kevin E. Bassler

Understanding the operation of biological and artificial networks remains a difficult and important challenge. To identify general principles, researchers are increasingly interested in surveying large collections of networks that are…

Machine Learning · Statistics 2022-01-14 Alex H. Williams , Erin Kunz , Simon Kornblith , Scott W. Linderman

Stochastic linear modelling proposed in Tissot, M\'emin & Cavalieri (J. Fluid Mech., vol. 912, 2021, A51) is based on classical conservation laws subject to a stochastic transport. Once linearised around the mean flow and expressed in the…

Fluid Dynamics · Physics 2022-07-27 Gilles Tissot , André Cavalieri , Etienne Mémin

Stability is an important characteristic of network models that has implications for other desirable aspects such as controllability. The stability of a Boolean network depends on various factors, such as the topology of its wiring diagram…

Chaotic Dynamics · Physics 2024-07-09 Karthik Chandrasekhar , Claus Kadelka , Reinhard Laubenbacher , David Murrugarra

We investigate the effect of noise on Random Boolean Networks. Noise is implemented as a probability $p$ that a node does not obey its deterministic update rule. We define two order parameters, the long-time average of the Hamming distance…

Biological Physics · Physics 2009-11-13 Tiago P. Peixoto , Barbara Drossel

Biclustering is a powerful approach to search for patterns in data, as it can be driven by a function that measures the quality of diverse types of patterns of interest. However, due to its computational complexity, the exploration of the…

Machine Learning · Computer Science 2021-04-27 Marcin Michalak , Jesús S. Aguilar-Ruiz

Random Boolean networks (RBNs) have been a popular model of genetic regulatory networks for more than four decades. However, most RBN studies have been made with random topologies, while real regulatory networks have been found to be…

Cellular Automata and Lattice Gases · Physics 2015-03-17 Rodrigo Poblanno-Balp , Carlos Gershenson

Finite dynamical systems (e.g. Boolean networks and logical models) have been used in modeling biological systems to focus attention on the qualitative features of the system, such as the wiring diagram. Since the analysis of such systems…

Molecular Networks · Quantitative Biology 2012-11-27 Alan Veliz-Cuba , Kristina Buschur , Rose Hamershock , Ariel Kniss , Esther Wolff , Reinhard Laubenbacher

Boolean networks are powerful frameworks for capturing the logic of gene-regulatory circuits, yet their combinatorial explosion hampers exhaustive analyses. Here, we present a systematic reduction of a 31-node Boolean model that describes…

Discrete Mathematics · Computer Science 2025-06-04 Alonso Espinoza , Eric Goles , Marco Montalva-Medel