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Many natural systems, such as neurons firing in the brain or basketball teams traversing a court, give rise to time series data with complex, nonlinear dynamics. We can gain insight into these systems by decomposing the data into segments…

We introduce simple models of genetic regulatory networks and we proceed to the mathematical analysis of their dynamics. The models are discrete time dynamical systems generated by piecewise affine contracting mappings whose variables…

Dynamical Systems · Mathematics 2007-05-23 Ricardo Coutinho , Bastien Fernandez , Ricardo Lima , Arnaud Meyroneinc

This paper proposes a new method to reverse engineer gene regulatory networks from experimental data. The modeling framework used is time-discrete deterministic dynamical systems, with a finite set of states for each of the variables. The…

Quantitative Methods · Quantitative Biology 2007-05-23 Reinhard Laubenbacher , Brandilyn Stigler

Data driven methods for time series forecasting that quantify uncertainty open new important possibilities for robot tasks with hard real time constraints, allowing the robot system to make decisions that trade off between reaction time and…

Machine Learning · Computer Science 2020-01-08 Sebastian Gomez-Gonzalez , Sergey Prokudin , Bernhard Scholkopf , Jan Peters

In this paper we investigate a neural network model in which weights between computational nodes are modified according to a local learning rule. To determine whether local learning rules are sufficient for learning, we encode the network…

Neural and Evolutionary Computing · Computer Science 2025-12-08 Jonathan Baxter

The time taken for gene expression varies not least because proteins vary in length considerably. This paper uses an abstract, tuneable Boolean regulatory network model to explore gene expression time variation. In particular, it is shown…

Biomolecules · Quantitative Biology 2016-03-16 Larry Bull

High dimensional time series are endemic in applications of machine learning such as robotics (sensor data), computational biology (gene expression data), vision (video sequences) and graphics (motion capture data). Practical nonlinear…

Machine Learning · Statistics 2011-07-26 Andreas C. Damianou , Michalis K. Titsias , Neil D. Lawrence

A properly designed controller can help improve the quality of experimental measurements or force a dynamical system to follow a completely new time-evolution path. Recent developments in deep reinforcement learning have made steep advances…

Statistical Mechanics · Physics 2025-02-26 Ruslan Mukhamadiarov

Dynamical systems are used to model a variety of phenomena in which the bifurcation structure is a fundamental characteristic. Here we propose a statistical machine-learning approach to derive lowdimensional models that automatically…

Quantitative Methods · Quantitative Biology 2015-06-11 Yohei Kondo , Kunihiko Kaneko , Shuji Ishihara

Modern data-driven machine learning system designs exploit inductive biases in architectural structure, invariance and equivariance requirements, task-specific loss functions, and computational optimization tools. Previous works have…

Neural and Evolutionary Computing · Computer Science 2025-03-04 Achref Jaziri , Sina Ditzel , Iuliia Pliushch , Visvanathan Ramesh

Random Boolean networks (RBNs) are models of genetic regulatory networks. It is useful to describe RBNs as self-organizing systems to study how changes in the nodes and connections affect the global network dynamics. This article reviews…

Adaptation and Self-Organizing Systems · Physics 2010-09-24 Carlos Gershenson

We introduce a self-consistent deep-learning framework which, for a noisy deterministic time series, provides unsupervised filtering, state-space reconstruction, identification of the underlying differential equations and forecasting.…

Machine Learning · Computer Science 2021-08-05 Zhe Wang , Claude Guet

Leveraging machine learning methods to solve constraint satisfaction problems has shown promising, but they are mostly limited to a static situation where the problem description is completely known and fixed from the beginning. In this…

Machine Learning · Computer Science 2025-09-23 Wook Lee , Frans A. Oliehoek

Learning interpretable representations of neural dynamics at a population level is a crucial first step to understanding how observed neural activity relates to perception and behavior. Models of neural dynamics often focus on either…

Machine Learning · Statistics 2025-01-13 Noga Mudrik , Yenho Chen , Eva Yezerets , Christopher J. Rozell , Adam S. Charles

We present a framework for discriminative sequence classification where the learner works directly in the high dimensional predictor space of all subsequences in the training set. This is possible by employing a new coordinate-descent…

Machine Learning · Computer Science 2010-08-04 Georgiana Ifrim , Carsten Wiuf

Methods of modeling cellular regulatory networks as diverse as differential equations and Boolean networks co-exist, however, without any closer correspondence to each other. With the example system of the fission yeast cell cycle control…

Molecular Networks · Quantitative Biology 2015-03-13 Maria Davidich , Stefan Bornholdt

Genetic regulatory networks are usually modeled by systems of coupled differential equations and by finite state models, better known as logical networks, are also used. In this paper we consider a class of models of regulatory networks…

Dynamical Systems · Mathematics 2015-06-26 Ricardo Lima , Edgardo Ugalde

Critical points separate distinct dynamical regimes of complex systems, often delimiting functional or macroscopic phases in which the system operates. However, the long-term prediction of critical regimes and behaviors is challenging given…

Physics and Society · Physics 2025-04-15 Xiangrong Wang , Dan Lu , Zongze Wu , Weina Xu , Hongru Hou , Yanqing Hu , Yamir Moreno

We introduce generative models for accelerating simulations of complex systems through learning and evolving their effective dynamics. In the proposed Generative Learning of Effective Dynamics (G-LED), instances of high dimensional data are…

Machine Learning · Computer Science 2024-02-28 Han Gao , Sebastian Kaltenbach , Petros Koumoutsakos

This paper explores a simple question: can we model the internal transformations of a neural network using dynamical systems theory? We introduce Koopman autoencoders to capture how neural representations evolve through network layers,…

Machine Learning · Computer Science 2025-05-20 Nishant Suresh Aswani , Saif Eddin Jabari