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Related papers: Separation of chiral particles in micro- or nanofl…

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Separation of enantiomers by flows is a promising chiral resolution method using cost-effective microfluidics. Notwithstanding a number of experimental and numerical studies, a fundamental understanding still remains elusive, and an…

Soft Condensed Matter · Physics 2016-11-11 Sunghan Ro , Juyeon Yi , Yong Woon Kim

Molecules that only differ by their chirality, so called enantiomers, often possess different properties with respect to their biological function. Therefore, the separation of enantiomers presents a prominent challenge in molecular biology…

Soft Condensed Matter · Physics 2009-11-11 Marcin Kostur , Michael Schindler , Peter Talkner , Peter Hänggi

We conceived a model experiment for a continuous separation strategy of chiral molecules (enantiomers) without the need of any chiral selector structure or derivatization agents: Micro-particles that only differ by their chirality are shown…

Statistical Mechanics · Physics 2015-06-11 Lukas Bogunovic , Marc Fliedner , Ralf Eichhorn , Sonja Wegener , Jan Regtmeier , Dario Anselmetti , Peter Reimann

Dynamics and separation of mixed chiral microswimmers are numerically investigated in a channel with regular arrays of rigid half-circle obstacles. For zero shear flow, transport behaviors are the same for different chiral particles: the…

Soft Condensed Matter · Physics 2015-05-12 Bao-quan Ai , Ya-feng He , Wei-rong Zhong

We show that plane parabolic flow in a microfluidic channel causes nonmotile helically-shaped bacteria to drift perpendicular to the shear plane. Net drift results from the preferential alignment of helices with streamlines, with a…

Mesoscale and Nanoscale Physics · Physics 2010-04-07 Marcos , Henry C. Fu , Thomas R. Powers , Roman Stocker

Optical forces can be chiral when they exhibit opposite signs for the two enantiomeric versions of a chiral molecule or particle. Such forces could be eventually used to separate enantiomers, which could find application in numerous…

We introduce a new mechanism for the propulsion and separation by chirality of small ferromagnetic particles suspended in a liquid. Under the action of a uniform d.c. magnetic field H and an a.c. electric field E isomers with opposite…

Soft Condensed Matter · Physics 2015-05-27 E. Kirkinis , A. V. Andreev , B. Spivak

We present a particle separation mechanism which induces motion of particles of different sizes in opposite directions. The mechanism is based on the combined action of a driving force and an entropic rectification of the Brownian…

Statistical Mechanics · Physics 2012-02-10 D. Reguera , A. Luque , P. S. Burada , G. Schmid , J. M. Rubí , P. Hänggi

Compared to isotropic liquids, orientational order of nematic liquid crystals makes their rheological properties more involved, and thus requires fine control of the flow parameters to govern the orientational patterns. In microfluidic…

Soft Condensed Matter · Physics 2020-01-03 Simon Čopar , Žiga Kos , Tadej Emeršič , Uroš Tkalec

Considerable effort has been directed towards the characterization of chiral mesoscale structures, as shown in chiral protein assemblies and carbon nanotubes. Here, we establish a thermally-driven hydrodynamic description for the actuation…

Soft Condensed Matter · Physics 2023-12-14 E. Kirkinis , A. V. Andreev , M. Olvera de la Cruz

Inertial effects should be considered for micro- and nano-swimmers moving in a low-density medium confined by irregular structures that create entropic barriers, where viscous effects are no longer paramount. Here, we present a separation…

Soft Condensed Matter · Physics 2024-05-03 Narender Khatri

Chiral optical forces exhibit opposite signs for the two enantiomeric versions of a chiral molecule or particle. If large enough, these forces might be able to separate enantiomers all optically, which would find numerous applications in…

We study colloidal particles in a nematic-liquid-crystal-filled microfluidic channel and show how elastic interactions between the particle and the channel wall lead to different particle dynamics compared with conventional microfluidics.…

Soft Condensed Matter · Physics 2017-07-31 Sourav Mondal , Apala Majumdar , Ian M. Griffiths

Ferrofluids kept in place by permanent magnet quadrupoles can act as liquid walls to surround a second non-magnetic inside, resulting in a liquid fluidic channel with diameter size ranging from mm down to less than 10 micrometer. Micro…

We present a simple model for the development of shear layers between parallel flows in confining channels. Such flows are important across a wide range of topics from diffusers, nozzles and ducts to urban air flow and geophysical fluid…

Fluid Dynamics · Physics 2018-04-09 GP Benham , AA Castrejon-Pita , IJ Hewitt , CP Please , RW Style , P Bird

Chemically patterned surfaces are of significant interest in the context of microfluidic applications. Miniaturization of such devices will eventually lead to structures on the nano-scale. Whereas on the micron scale purely macroscopic…

Soft Condensed Matter · Physics 2007-05-23 Markus Rauscher , S. Dietrich

Chiral optical forces present an exciting avenue into the separation of enantiomers in an all-optical fashion. In this work, we explore via numerical simulations and analytical calculations the feasibility of the separation of chiral…

Liquid-liquid phase separation of liquids exhibiting interconversion between alternative states has been proposed as an underlying mechanism for fluid polyamorphism, and may be of relevance to protein function and intracellular…

Statistical Mechanics · Physics 2021-12-08 Betul Uralcan , Thomas J. Longo , Mikhail A. Anisimov , Frank H. Stillinger , Pablo G. Debenedetti

Trapping macromolecules in nanopits finds multifarious applications in polymer separation, filtering biomolecules etc. However, tuning the locomotion of polymers in channels of nanoscopic dimensions is greatly restricted by the comparative…

Fluid Dynamics · Physics 2016-05-10 Sree Hari P D , Chirodeep Bakli , Suman Chakraborty

We introduce the use of superchiral surface waves for the all-optical separation of chiral compounds. Using a combination of electrodynamics modeling and analytical techniques, we show that the proposed approach provides chiral optical…

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