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We investigate binary mixtures undergoing phase separation after a second (deeper) temperature quench into two- and three-phase coexistence regions. The analysis is based on a lattice theory previously developed for gas-liquid separation in…

Soft Condensed Matter · Physics 2019-11-22 Pablo de Castro , Peter Sollich

In this study, we present a comprehensive exploration of formation of different phases in lipid molecules using a coarse-grained implicit solvent model, where each lipid molecule is represented as a rigid, three-bead rod-like structure. Our…

Soft Condensed Matter · Physics 2023-12-13 Biplab Bawali , Alokmay Datta , Jayashree Saha

We use a lattice model of a ternary mixture containing saturated and unsaturated lipids with cholesterol (Chol), to study the structural properties characterizing the coexistence between the liquid-disordered and liquid-ordered phases.…

Soft Condensed Matter · Physics 2023-10-24 Tanmoy Sarkar , Oded Farago

Mixtures of several macromolecular species can lead to the formation of higher-order structures that often display non-ideal mixing behavior. In this work, we propose a minimal model of a quaternary system which considers the formation of a…

Soft Condensed Matter · Physics 2022-12-14 Ruoyao Zhang , Sheng Mao , Mikko Haataja

Atomistic molecular dynamics simulations have reached a degree of maturity that makes it possible to investigate the lipid polymorphism of model bilayers over a wide range of temperatures. However if both the fluid $L_{\alpha}$ and tilted…

Soft Condensed Matter · Physics 2021-02-09 Vivien Walter , Céline Ruscher , Adrien Gola , Carlos M. Marques , Olivier Benzerara , Fabrice Thalmann

Multiphase field models have emerged as an important computational tool for understanding biological tissue while resolving single-cell properties. While they have successfully reproduced many experimentally observed behaviors of living…

Soft Condensed Matter · Physics 2025-02-13 Michael Chiang , Austin Hopkins , Benjamin Loewe , Davide Marenduzzo , M. Cristina Marchetti

We employ a molecular model to study a ternary mixture of saturated lipid, with tails of sixteen carbons, a mono unsaturated lipid with tails of eighteen carbons, and cholesterol. The model, solved within mean-field theory, produces several…

Biological Physics · Physics 2009-11-11 R. Elliott , I. Szleifer , M. Schick

This work reports an investigation into the solid phase behavior and melting behavior of tetracosane (C24H50) monolayers and bilayers physisorbed onto the graphite basal plane using molecular dynamics simulations performed in the constant…

Soft Condensed Matter · Physics 2007-05-23 Cary Pint

Lipid structures exhibit complex and highly dynamic lateral structure; and changes in lipid density and fluidity are believed to play an essential role in membrane targeting and function. The dynamic structure of liquids on the molecular…

Soft Condensed Matter · Physics 2016-12-21 Neda Dadashvand , Christina M. Othon

Controlling the coupling between different degrees of freedom in many-body systems is a powerful technique for engineering novel phases of matter. We create a bilayer system of two-dimensional (2D) ultracold Bose gases and demonstrate the…

Finite domains of a Langmuir monolayer in a phase with tilted molecules can be modeled by a simple elastic free energy of an XY order parameter with isotropic and anisotropic line tension terms. The domains can and often do contain…

Soft Condensed Matter · Physics 2016-08-31 David Pettey , T. C. Lubensky

We study the relaxation dynamics of a compressible bilayer vesicle with an asymmetry in the viscosity of the inner and outer fluid medium. First we explore the stability of the vesicle free energy which includes a coupling between the…

Soft Condensed Matter · Physics 2017-01-03 T. V. Sachin Krishnan , Ryuichi Okamoto , Shigeyuki Komura

Thermally excited capillary waves at fluid interfaces in binary liquid mixtures exhibit simultaneously both density and composition fluctuations. Based on a density functional theory for inhomogeneous binary liquid mixtures we derive an…

Soft Condensed Matter · Physics 2009-11-11 Thorsten Hiester , S. Dietrich , Klaus Mecke

Polarized ferrofluids, lipid monolayers and magnetic bubbles form domains with deformable boundaries. Stability analysis of these domains depends on a family of nontrivial integrals. We present a closed form evaluation of these integrals as…

Soft Condensed Matter · Physics 2009-10-30 Jose A. Miranda , Michael Widom

The elastic properties of two-component bilayer membranes are studied using a coarse grain model for amphiphilic molecules. The two species of amphiphiles considered here differ only in their length. Molecular Dynamics simulations are…

Soft Condensed Matter · Physics 2007-05-23 Alberto Imparato , Julian C. Shillcock , Reinhard Lipowsky

A new model is proposed to explain coiling of myelins composed of fluid bilayers. This model allows the constituent bilayer cylinders of a myelin to be non-coaxial and the bilayer lateral tension to vary from bilayer to bilayer. The…

Soft Condensed Matter · Physics 2009-11-11 Jung-Ren Huang

Membrane budding has been extensively studied as an equilibrium process attributed to the formation of coexisting domains or changes in the vesicle area to volume ratio (reduced volume). In contrast, non-equilibrium budding remains…

Biological Physics · Physics 2013-03-27 Thomas Franke , Christian T. Leirer , Achim Wixforth , Nily Dan , Matthias F. Schneider

Since the lipid raft model was developed at the end of the last century, it became clear that the specific molecular arrangements of phospholipid assemblies within a membrane have profound implications in a vast range of physiological…

Soft Condensed Matter · Physics 2024-04-19 Alexander P. Fellows , Ben John , Martin Wolf , Martin Thämer

In a companion paper, we put forth a thermodynamic model for complex formation via a chemical reaction involving multiple macromolecular species, which may subsequently undergo liquid-liquid phase separation and a further transition into a…

Biological Physics · Physics 2024-07-26 Ruoyao Zhang , Sheng Mao , Mikko P. Haataja

We study phase separation in mixed monolayers of neutral and highly negatively charged lipids, induced by the addition of divalent positively charged counterions. We find good agreement between experiments on mixtures of pip2 and sopc and…