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The biological membrane, which compartmentalizes the cell and its organelles, exhibit wide variety of macroscopic shapes of varying morphology and topology. A systematic understanding of the relation of membrane shapes to composition,…

Biological Physics · Physics 2011-09-23 N. Ramakrishnan , P. B. Sunil Kumar , John H. Ipsen

This paper concerns a model for tumor cell migration through the surrounding extracellular matrix by considering mass balance phenomena involving the chemical interactions produced on the cell surface. The well-posedness of this model is…

Analysis of PDEs · Mathematics 2015-09-03 J. Nieto , L. Urrutia

While it is commonly observed that the shape dynamics of mammalian cells can undergo large random fluctuations, theoretical models aiming at capturing cell mechanics often focus on the deterministic part of the motion. In this paper, we…

Biological Physics · Physics 2021-04-07 Vikram Deshpande , Antonio DeSimone , Robert McMeeking , Pierre Recho

This article covers thermodynamic, dynamic, and kinetic models that are suitable for the analysis of wetting, adsorption, and related interfacial phenomena in colloidal and multiphase systems. Particular emphasis is made on describing…

Soft Condensed Matter · Physics 2025-09-03 Carlos E. Colosqui

Starting from the working hypothesis that both physics and the corresponding mathematics have to be described by means of discrete concepts on the Planck scale, one of the many problems one has to face in this enterprise is to find the…

High Energy Physics - Theory · Physics 2008-11-26 Manfred Requardt

In cell membranes, proteins and lipids are organized into sub-micrometric nanodomains of varying size, shape and composition, performing specific functions. Despite their biological importance, the detailed morphology of these nanodomains…

Heterogeneities in the cell membrane due to coexisting lipid phases have been conjectured to play a major functional role in cell signaling and membrane trafficking. Thereby the material properties of multiphase systems, such as the line…

Soft Condensed Matter · Physics 2013-04-17 Stefan Semrau , Timon Idema , Laurent Holtzer , Thomas Schmidt , Cornelis Storm

In the era of foundation models and Large Language Models (LLMs), Euclidean space has been the de facto geometric setting for machine learning architectures. However, recent literature has demonstrated that this choice comes with…

Machine Learning · Computer Science 2025-11-26 Neil He , Jiahong Liu , Buze Zhang , Ngoc Bui , Ali Maatouk , Menglin Yang , Irwin King , Melanie Weber , Rex Ying

A molecular rotor mechanism is proposed to explain weak magnetic field effects in biology. Despite being nanoscale (1 nm), this rotor exhibits quantum superposition and interference. Analytical modeling shows its quantum dynamics are highly…

Biological Physics · Physics 2025-12-18 V. N. Binhi

Granular and nanoscale materials containing a relatively small number of constituents have been studied to discover how their properties differ from their macroscopic counterparts. These studies are designed to test how far the known…

Statistical Mechanics · Physics 2007-05-23 A. K. Rajagopal , C. S. Pande , Sumiyoshi Abe

We analyse symmetry breaking in general gauge theories paying particular attention to the underlying geometry of the theory. In this context we find two natural metrics upon the vacuum manifold: a Euclidean metric associated with the scalar…

High Energy Physics - Theory · Physics 2010-02-03 Nathan. F. Lepora

This work investigates the geometrical properties of self-gravitating $N$-body systems from the perspective established by Henri Poincar\'e and Albert Einstein concerning the operational nature of measured geometry. Utilizing recent…

General Relativity and Quantum Cosmology · Physics 2026-05-29 Maria I. R. Lourenço , Julian Barbour , Francisco S. N. Lobo

An attempt is made to extend some of the basic paradigms of dynamics, from the viewpoint of (continuous) flows, to non-metric manifolds.

Dynamical Systems · Mathematics 2011-03-01 Alexandre Gabard , David Gauld

Mechanical cues from the extracellular microenvironment play a central role in regulating the structure, function and fate of living cells. Nevertheless, the precise nature of the mechanisms and processes underlying this crucial cellular…

Biological Physics · Physics 2015-06-23 Ariel Livne , Eran Bouchbinder , Benjamin Geiger

Experience collected in mesoscopic dynamic modeling of externally driven systems indicates absence of potentials that could play role of equilibrium or nonequilibrium thermodynamic potentials yet their thermo-dynamics-like modeling is often…

Statistical Mechanics · Physics 2017-02-01 Miroslav Grmela

We elaborate on a recently proposed geometric framework for scalar effective field theories. Starting from the action, a metric can be identified that enables the construction of geometric quantities on the associated functional manifold.…

High Energy Physics - Theory · Physics 2025-04-14 Timothy Cohen , Xiaochuan Lu , Zhengkang Zhang

The relationship between micro-structure and macro-structure of complex systems using information geometry has been dealt by several authors. From this perspective, we are going to apply it as a geometrical structure connecting both…

General Finance · Quantitative Finance 2013-10-17 M. E. Kahil

This manuscript introduces novel approaches to three phenomena. First, we extend the algebraic formulation of kinetic theory within the contact framework by making explicit the gauge freedom, thereby obtaining a formulation in which the…

Mathematical Physics · Physics 2025-10-29 Begüm Ateşli , Oğul Esen , Miroslav Grmela , Michal Pavelka

Water behaves very differently at surfaces and under extreme confinement, but the boundary between these two regimes has remained unclear. Despite evidence that interfacial effects persist under sub-nanometre confinement, the…

Chemical Physics · Physics 2025-12-15 Xavier R. Advincula , Christoph Schran , Angelos Michaelides

Cell membranes separate the cell interior from the external environment. They are constituted by a variety of lipids; their composition determines the dynamics of membrane proteins and affects the ability of the cells to adapt. Even though…

Quantitative Methods · Quantitative Biology 2018-10-04 Nicola Galvanetto