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An individualized decision rule (IDR) is a decision function that assigns each individual a given treatment based on his/her observed characteristics. Most of the existing works in the literature consider settings with binary or finitely…

Methodology · Statistics 2023-01-31 Hengrui Cai , Chengchun Shi , Rui Song , Wenbin Lu

Recent works have shown that tackling offline reinforcement learning (RL) with a conditional policy produces promising results. The Decision Transformer (DT) combines the conditional policy approach and a transformer architecture, showing…

Machine Learning · Computer Science 2023-05-26 Taku Yamagata , Ahmed Khalil , Raul Santos-Rodriguez

Individualized treatment rules (ITRs) tailor treatments according to individual patient characteristics. They can significantly improve patient care and are thus becoming increasingly popular. The data collected during randomized clinical…

Methodology · Statistics 2015-06-30 Stanislav Minsker , Ying-Qi Zhao , Guang Cheng

Active learning is usually applied to acquire labels of informative data points in supervised learning, to maximize accuracy in a sample-efficient way. However, maximizing the accuracy is not the end goal when the results are used for…

Machine Learning · Statistics 2021-10-22 Louis Filstroff , Iiris Sundin , Petrus Mikkola , Aleksei Tiulpin , Juuso Kylmäoja , Samuel Kaski

Clinical decision-making is a feedback system where risk estimates influence treatment, which in turn changes disease trajectories, and both shape clinicians' measurement practices. Static prediction often fails clinically: models trained…

Artificial Intelligence · Computer Science 2026-05-19 Pujun Feng , Xiaoyu Guo , Seyed Ehsan Saffari , Min Hun Lee , Siew-Kei Lam , Erik Cambria , Xibin Sun , Yangtao Zhou , Tong Yang , Xiaoyu Zhang , Tao Tan , Yue Sun , Bin Cui

We present a dynamic learning paradigm for "programming" a general quantum computer. A learning algorithm is used to find the control parameters for a coupled qubit system, such that the system at an initial time evolves to a state in which…

Quantum Physics · Physics 2008-08-12 E. C. Behrman , J. E. Steck , P. Kumar , K. A. Walsh

In this paper, we place deep Q-learning into a control-oriented perspective and study its learning dynamics with well-established techniques from robust control. We formulate an uncertain linear time-invariant model by means of the neural…

Machine Learning · Computer Science 2022-11-08 Balazs Varga , Balazs Kulcsar , Morteza Haghir Chehreghani

Clinical diagnosis guidelines aim at specifying the steps that may lead to a diagnosis. Inspired by guidelines, we aim to learn the optimal sequence of actions to perform in order to obtain a correct diagnosis from electronic health…

Machine Learning · Computer Science 2023-11-16 Lillian Muyama , Antoine Neuraz , Adrien Coulet

In this paper, two Q-learning (QL) methods are proposed and their convergence theories are established for addressing the model-free optimal control problem of general nonlinear continuous-time systems. By introducing the Q-function for…

Systems and Control · Computer Science 2014-10-14 Biao Luo , Derong Liu , Tingwen Huang

We consider optimal regimes for algorithm-assisted human decision-making. Such regimes are decision functions of measured pre-treatment variables and, by leveraging natural treatment values, enjoy a "superoptimality" property whereby they…

Methodology · Statistics 2024-02-23 Mats J. Stensrud , Julien Laurendeau , Aaron L. Sarvet

We present a deep learning-based approach to studying dynamic clinical behavioral regimes in diverse non-randomized healthcare settings. Our proposed methodology - deep causal behavioral policy learning (DC-BPL) - uses deep learning…

Machine Learning · Statistics 2025-03-06 Jonas Knecht , Anna Zink , Jonathan Kolstad , Maya Petersen

An individualized dose rule recommends a dose level within a continuous safe dose range based on patient level information such as physical conditions, genetic factors and medication histories. Traditionally, personalized dose finding…

Methodology · Statistics 2020-07-21 Liangyu Zhu , Wenbin Lu , Michael R. Kosorok , Rui Song

Learning is a complex dynamical process shaped by a range of interconnected decisions. Careful design of hyperparameter schedules for artificial neural networks or efficient allocation of cognitive resources by biological learners can…

Disordered Systems and Neural Networks · Physics 2025-07-11 Francesca Mignacco , Francesco Mori

In many real-world scenarios involving high-stakes and safety implications, a human decision-maker (HDM) may receive recommendations from an artificial intelligence while holding the ultimate responsibility of making decisions. In this…

Machine Learning · Computer Science 2024-07-18 Ioannis Faros , Aditya Dave , Andreas A. Malikopoulos

We consider the estimation of treatment effects in settings when multiple treatments are assigned over time and treatments can have a causal effect on future outcomes or the state of the treated unit. We propose an extension of the…

Econometrics · Economics 2021-06-18 Greg Lewis , Vasilis Syrgkanis

Meta continual learning algorithms seek to train a model when faced with similar tasks observed in a sequential manner. Despite promising methodological advancements, there is a lack of theoretical frameworks that enable analysis of…

Machine Learning · Computer Science 2020-10-12 R. Krishnan , Prasanna Balaprakash

Existing strategies for determining the optimal treatment or monitoring strategy typically assume unlimited access to resources. However, when a health system has resource constraints, such as limited funds, access to medication, or…

Applications · Statistics 2019-03-18 Ellen C Caniglia , Eleanor J Murray , Miguel A Hernan , Zach Shahn

We propose a dynamic allocation procedure that increases power and efficiency when measuring an average treatment effect in sequential randomized trials exploiting some subjects' previous assessed responses. Subjects arrive sequentially and…

Methodology · Statistics 2021-06-03 Adam Kapelner , Abba Krieger

Recent advances in dynamic treatment regimes (DTRs) facilitate the search for optimal treatments, which are tailored to individuals' specific needs and able to maximize their expected clinical benefits. However, existing algorithms relying…

Machine Learning · Statistics 2024-10-18 Hanwen Ye , Wenzhuo Zhou , Ruoqing Zhu , Annie Qu

Q-learning is a simple and powerful tool in solving dynamic problems where environments are unknown. It uses a balance of exploration and exploitation to find an optimal solution to the problem. In this paper, we propose using four basic…

Machine Learning · Computer Science 2016-09-07 Wilfredo Badoy , Kardi Teknomo
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