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This paper investigates the problem of modeling Internet images and associated text or tags for tasks such as image-to-image search, tag-to-image search, and image-to-tag search (image annotation). We start with canonical correlation…

Computer Vision and Pattern Recognition · Computer Science 2013-09-13 Yunchao Gong , Qifa Ke , Michael Isard , Svetlana Lazebnik

Classical canonical correlation analysis (CCA) requires matrices to be low dimensional, i.e. the number of features cannot exceed the sample size. Recent developments in CCA have mainly focused on the high-dimensional setting, where the…

Methodology · Statistics 2021-06-09 Wenjia Wang , Yi-Hui Zhou

Kernel principal component analysis (KPCA) is a well-recognized nonlinear dimensionality reduction method that has been widely used in nonlinear fault detection tasks. As a kernel trick-based method, KPCA inherits two major problems. First,…

Machine Learning · Computer Science 2024-10-28 Zelin Ren , Xuebing Yang , Yuchen Jiang , Wensheng Zhang

This article critically assesses the utility of the classical statistical technique of Canonical Correlation Analysis (CCA) for studying spatial associations and proposes a new approach to enhance it. Unlike bivariate correlation analysis,…

Methodology · Statistics 2026-02-12 Zhenzhi Jiao , Angela Yao , Ran Tao , Jean-Claude Thill

Quantitative Structure-Activity Relationship (QSAR) modeling is a cornerstone of computational drug discovery. This research demonstrates the successful application of a Quantum Multiple Kernel Learning (QMKL) framework to enhance QSAR…

Quantum Physics · Physics 2025-12-17 Alejandro Giraldo , Daniel Ruiz , Mariano Caruso , Javier Mancilla , Guido Bellomo

Recently proposed automatic pathological speech detection approaches rely on spectrogram input representations or wav2vec2 embeddings. These representations may contain pathology irrelevant uncorrelated information, such as changing…

Audio and Speech Processing · Electrical Eng. & Systems 2024-09-27 Yacouba Kaloga , Shakeel A. Sheikh , Ina Kodrasi

Given two sets of variables, derived from a common set of samples, sparse Canonical Correlation Analysis (CCA) seeks linear combinations of a small number of variables in each set, such that the induced canonical variables are maximally…

Machine Learning · Statistics 2016-05-31 Megasthenis Asteris , Anastasios Kyrillidis , Oluwasanmi Koyejo , Russell Poldrack

This paper considers the problem of canonical-correlation analysis (CCA) (Hotelling, 1936) and, more broadly, the generalized eigenvector problem for a pair of symmetric matrices. These are two fundamental problems in data analysis and…

Machine Learning · Computer Science 2016-05-30 Rong Ge , Chi Jin , Sham M. Kakade , Praneeth Netrapalli , Aaron Sidford

Motivated by the recently shown connection between self-attention and (kernel) principal component analysis (PCA), we revisit the fundamentals of PCA. Using the difference-of-convex (DC) framework, we present several novel formulations and…

Machine Learning · Computer Science 2025-10-22 Jan Quan , Johan Suykens , Panagiotis Patrinos

We consider the problem of sparse canonical correlation analysis (CCA), i.e., the search for two linear combinations, one for each multivariate, that yield maximum correlation using a specified number of variables. We propose an efficient…

Computation · Statistics 2008-01-18 Ami Wiesel , Mark Kliger , Alfred O. Hero

We present an extension of sparse Canonical Correlation Analysis (CCA) designed for finding multiple-to-multiple linear correlations within a single set of variables. Unlike CCA, which finds correlations between two sets of data where the…

Machine Learning · Statistics 2015-11-23 Maria De-Arteaga , Artur Dubrawski , Peter Huggins

Cross-modal retrieval aims to retrieve data in one modality by a query in another modality, which has been a very interesting research issue in the field of multimedia, information retrieval, and computer vision, and database. Most existing…

Multimedia · Computer Science 2021-05-06 Donghuo Zeng , Yi Yu , Keizo Oyama

Virtual screening (VS) is a critical step in computer-aided drug discovery, aiming to identify molecules that bind to a specific target receptor like protein. Traditional VS methods, such as docking, are often too time-consuming for…

Artificial Intelligence · Computer Science 2024-07-30 Jin Han , Yun Hong , Wu-Jun Li

Virtual screening (VS) is widely used during computational drug discovery to reduce costs. Chemogenomics-based virtual screening (CGBVS) can be used to predict new compound-protein interactions (CPIs) from known CPI network data using…

Quantitative Methods · Quantitative Biology 2021-05-04 Masahito Ohue , Takuro Yamazaki , Tomohiro Ban , Yutaka Akiyama

Computational screening of naturally occurring proteins has the potential to identify efficient catalysts among the hundreds of millions of sequences that remain uncharacterized. Current experimental methods remain time, cost and labor…

Quantitative Methods · Quantitative Biology 2024-02-13 Peter G. Mikhael , Itamar Chinn , Regina Barzilay

We study the problem of column selection in large-scale kernel canonical correlation analysis (KCCA) using the Nystr\"om approximation, where one approximates two positive semi-definite kernel matrices using "landmark" points from the…

Machine Learning · Computer Science 2016-02-09 Weiran Wang

Imaging genetic research has essentially focused on discovering unique and co-association effects, but typically ignoring to identify outliers or atypical objects in genetic as well as non-genetics variables. Identifying significant…

Machine Learning · Statistics 2016-06-02 Md Ashad Alam , Yu-Ping Wang

Cross-modality retrieval encompasses retrieval tasks where the fetched items are of a different type than the search query, e.g., retrieving pictures relevant to a given text query. The state-of-the-art approach to cross-modality retrieval…

Information Retrieval · Computer Science 2018-04-17 Matthias Dorfer , Jan Schlüter , Andreu Vall , Filip Korzeniowski , Gerhard Widmer

We aim to analyze the relation between two random vectors that may potentially have both different number of attributes as well as realizations, and which may even not have a joint distribution. This problem arises in many practical…

Machine Learning · Statistics 2015-11-12 Hoang-Vu Nguyen , Jilles Vreeken

In this paper linear canonical correlation analysis (LCCA) is generalized by applying a structured transform to the joint probability distribution of the considered pair of random vectors, i.e., a transformation of the joint probability…

Methodology · Statistics 2015-06-03 Koby Todros , Alfred O. Hero
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