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We introduce computational causal inference as an interdisciplinary field across causal inference, algorithms design and numerical computing. The field aims to develop software specializing in causal inference that can analyze massive…

Computation · Statistics 2020-07-22 Jeffrey C. Wong

To understand the biology of cancer, joint analysis of multiple data modalities, including imaging and genomics, is crucial. The involved nature of gene-microenvironment interactions necessitates the use of algorithms which treat both data…

Signal Processing · Electrical Eng. & Systems 2018-02-27 Vaishnavi Subramanian , Benjamin Chidester , Jian Ma , Minh N. Do

The drug discovery process involves several tasks to be performed in vivo, in vitro and in silico. Molecular docking is a task typically performed in silico. It aims at finding the three-dimensional pose of a given molecule when it…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-01-21 Davide Gadioli , Gianluca Palermo , Stefano Cherubin , Emanuele Vitali , Giovanni Agosta , Candida Manelfi , Andrea R. Beccari , Carlo Cavazzoni , Nico Sanna , Cristina Silvano

In this study, a scalable online kernel learning framework is proposed for estimating bidirectional causal effects in systems characterized by mutual dependence and heteroskedasticity. Traditional causal inference often focuses on…

Machine Learning · Statistics 2025-11-24 Masahiro Tanaka

This paper studies kernel PCA in a decentralized setting, where data are distributively observed with full features in local nodes and a fusion center is prohibited. Compared with linear PCA, the use of kernel brings challenges to the…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-11-30 Fan He , Ruikai Yang , Lei Shi , Xiaolin Huang

Interpreting the internal reasoning of vision-language models is essential for deploying AI in safety-critical domains. Concept-based explainability provides a human-aligned lens by representing a model's behavior through semantically…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Ehud Gordon , Meir Yossef Levi , Guy Gilboa

Kernel-based conditional independence (KCI) testing is a powerful nonparametric method commonly employed in causal discovery tasks. Despite its flexibility and statistical reliability, cubic computational complexity limits its application…

Machine Learning · Computer Science 2025-12-05 Oliver Schacht , Biwei Huang

Combining the predictions of multiple trained models through ensembling is generally a good way to improve accuracy by leveraging the different learned features of the models, however it comes with high computational and storage costs.…

Machine Learning · Computer Science 2024-07-09 Stefan Horoi , Albert Manuel Orozco Camacho , Eugene Belilovsky , Guy Wolf

Automatic image annotation is among the fundamental problems in computer vision and pattern recognition, and it is becoming increasingly important in order to develop algorithms that are able to search and browse large-scale image…

Computer Vision and Pattern Recognition · Computer Science 2017-06-02 Tiberio Uricchio , Lamberto Ballan , Lorenzo Seidenari , Alberto Del Bimbo

Conditional independence testing is an important problem, especially in Bayesian network learning and causal discovery. Due to the curse of dimensionality, testing for conditional independence of continuous variables is particularly…

Machine Learning · Computer Science 2012-02-20 Kun Zhang , Jonas Peters , Dominik Janzing , Bernhard Schoelkopf

Kernel methods have been proven to be a powerful tool for the integration and analysis of highthroughput technologies generated data. Kernels offer a nonlinear version of any linear algorithm solely based on dot products. The kernelized…

Applications · Statistics 2024-11-27 Mitja Briscik , Marie-Agnès Dillies , Sébastien Déjean

Principal component analysis (PCA) is largely adopted for chemical process monitoring and numerous PCA-based systems have been developed to solve various fault detection and diagnosis problems. Since PCA-based methods assume that the…

Machine Learning · Computer Science 2017-12-13 Haitao Zhao

Deep learning models often function as black boxes, providing no straightforward reasoning for their predictions. This is particularly true for computer vision models, which process tensors of pixel values to generate outcomes in tasks such…

Computer Vision and Pattern Recognition · Computer Science 2024-10-02 Sachin Karmani , Thanushon Sivakaran , Gaurav Prasad , Mehmet Ali , Wenbo Yang , Sheyang Tang

Multimodal language analysis often considers relationships between features based on text and those based on acoustical and visual properties. Text features typically outperform non-text features in sentiment analysis or emotion recognition…

Machine Learning · Computer Science 2019-12-03 Zhongkai Sun , Prathusha Sarma , William Sethares , Yingyu Liang

We introduce Block Sparse Canonical Correlation Analysis which estimates multiple pairs of canonical directions (together a "block") at once, resulting in significantly improved orthogonality of the sparse directions which, we demonstrate,…

Machine Learning · Statistics 2020-01-22 Omid Shams Solari , Rojin Safavi , James B. Brown

Canonical correlation analysis (CCA) has become a key tool for population neuroimaging, allowing investigation of associations between many imaging and non-imaging measurements. As other variables are often a source of variability not of…

Methodology · Statistics 2024-01-09 Anderson M. Winkler , Olivier Renaud , Stephen M. Smith , Thomas E. Nichols

Due to the complexity of cancer, clustering algorithms have been used to disentangle the observed heterogeneity and identify cancer subtypes that can be treated specifically. While kernel based clustering approaches allow the use of more…

Machine Learning · Statistics 2018-11-21 Nora K. Speicher , Nico Pfeifer

Multispectral imaging is an important technique for improving the readability of written or printed text where the letters have faded, either due to deliberate erasing or simply due to the ravages of time. Often the text can be read simply…

Computer Vision and Pattern Recognition · Computer Science 2018-07-20 Corneliu T. C. Arsene , Stephen Church , Mark Dickinson

We present Deep Generalized Canonical Correlation Analysis (DGCCA) -- a method for learning nonlinear transformations of arbitrarily many views of data, such that the resulting transformations are maximally informative of each other. While…

Machine Learning · Computer Science 2017-06-16 Adrian Benton , Huda Khayrallah , Biman Gujral , Dee Ann Reisinger , Sheng Zhang , Raman Arora

Principal component analysis (PCA) is a widespread technique for data analysis that relies on the covariance-correlation matrix of the analyzed data. However to properly work with high-dimensional data, PCA poses severe mathematical…

Quantitative Methods · Quantitative Biology 2018-10-18 Luigi Leonardo Palese
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