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Malaria is transmitted to vertebrates via a mosquito bite, during which rod-like and crescent-shaped parasites, called sporozoites, are injected into the skin of the host. Searching for a blood capillary to penetrate, sporozoites move…

Cell Behavior · Quantitative Biology 2014-10-24 Anna Battista , Friedrich Frischknecht , Ulrich S. Schwarz

Reorientation (turning in plane) plays a critical role for all robots in any field application, especially those that in confined spaces. While important, reorientation remains a relatively unstudied problem for robots, including limbless…

Robotics · Computer Science 2022-03-04 Tianyu Wang , Baxi Chong , Yuelin Deng , Ruijie Fu , Howie Choset , Daniel I. Goldman

We introduce a generic, purely mechanical model for environment sensitive motion of mammalian cells that is applicable to chemotaxis, haptotaxis, and durotaxis as modes of motility. It is able to theoretically explain all relevant…

Cell Behavior · Quantitative Biology 2016-05-09 Patrick Bitter , Kristof Leon Beck , Peter Lenz

Collective migration -- the directed, coordinated motion of many self-propelled agents -- is a fascinating emergent behavior exhibited by active matter that has key functional implications for biological systems. Extensive studies have…

Biological Physics · Physics 2022-06-07 Tapomoy Bhattacharjee , Daniel B. Amchin , Ricard Alert , J. A. Ott , Sujit S. Datta

Graph spectral analysis can yield meaningful embeddings of graphs by providing insight into distributed features not directly accessible in nodal domain. Recent efforts in graph signal processing have proposed new decompositions-e.g., based…

Machine Learning · Computer Science 2019-03-07 Miljan Petrović , Thomas A. W. Bolton , Maria Giulia Preti , Raphaël Liégeois , Dimitri Van De Ville

Neural systems show a modular and typically also a hierarchical organisation across different levels and across different species. Topology relates to function, but it is also influences dynamics as earlier studies showed its effect on…

Neurons and Cognition · Quantitative Biology 2014-05-15 Marcus Kaiser

We present what we believe to be the first formal verification of a biologically realistic (nonlinear ODE) model of a neural circuit in a multicellular organism: Tap Withdrawal (TW) in \emph{C. Elegans}, the common roundworm. TW is a…

Logic in Computer Science · Computer Science 2015-03-24 Md. Ariful Islam , Richard DeFrancisco , Chuchu Fan , Radu Grosu , Sayan Mitra , Scott A. Smolka

To survive in ever-changing environments, living organisms need to continuously combine the ongoing external inputs they receive, representing present conditions, with their dynamical internal state, which includes influences of past…

Neurons and Cognition · Quantitative Biology 2024-02-09 Maria Sol Vidal-Saez , Oscar Vilarroya , Jordi Garcia-Ojalvo

Nonlinear dynamics of the electron-cyclotron instability driven by the electron $\mathbf{E\times B}$ current in crossed electric and magnetic field is studied. In nonlinear regime the instability proceeds by developing a large amplitude…

Recently, long and slender living worms have garnered significant interest because of their impressive ability to exhibit diverse emergent behaviors in highly entangled physical and topological conditions. These worms can form an active…

Topological phenomena typically govern the behavior of delocalized waves, giving rise to robust transport in electronic, photonic, and mechanical systems. Whether similar principles can directly control the motion of a localized particle,…

Fluid Dynamics · Physics 2026-03-13 Ethan Andersson , Valeri Frumkin

Life presents fascinating examples of self-organization and emergent phenomena. In multi-cellular organisms, a multitude of cells interact to form and maintain highly complex body plans of well-defined size. In this thesis, we investigate…

Biological Physics · Physics 2016-08-25 Steffen Werner

We report on the effects of temporal modulation of the driving force on a particular class of localized states, known as worms, that have been observed in electroconvection in nematic liquid crystals. The worms consist of the superposition…

Pattern Formation and Solitons · Physics 2009-11-07 Carina Kamaga , Michael Dennin

The existence of many-body mobility edges in closed quantum systems has been the focus of intense debate after the emergence of the description of the many-body localization phenomenon. Here we propose that this issue can be settled in…

Strongly Correlated Electrons · Physics 2019-05-01 Xing Bo Wei , Chen Cheng , Gao Xianlong , Rubem Mondaini

A dynamic self-organized morphology is the hallmark of network-shaped organisms like slime moulds and fungi. Organisms continuously re-organize their flexible, undifferentiated body plans to forage for food. Among these organisms the slime…

Biological Physics · Physics 2019-03-27 Karen Alim

Many dynamical systems found in biology, ranging from genetic circuits to the human brain to human social systems, are inherently computational. Although extensive research has explored their resulting functions and behaviors, the…

Neurons and Cognition · Quantitative Biology 2025-04-15 Junang Li , Andrew M. Leifer , David H. Wolpert

Centipedes exhibit great maneuverability in diverse environments due to their many legs and body-driven control. By leveraging similar morphologies and control strategies, their robotic counterparts also demonstrate effective terrestrial…

Robotics · Computer Science 2025-06-04 Esteban Flores , Baxi Chong , Daniel Soto , Daniel I. Goldman

This work is concerned with a representation of shapes that disentangles fine, local and possibly repeating geometry, from global, coarse structures. Achieving such disentanglement leads to two unrelated advantages: i) a significant…

Computer Vision and Pattern Recognition · Computer Science 2022-04-06 Luca Morreale , Noam Aigerman , Paul Guerrero , Vladimir G. Kim , Niloy J. Mitra

Essentially all biology is active and dynamic. Biological entities autonomously sense, com- pute, and respond using energy-coupled ratchets that can produce force and do work. The cytoskeleton, along with its associated proteins and motors,…

Soft Condensed Matter · Physics 2017-03-28 Kasimira T. Stanhope , Vikrant Yadav , Christian D. Santangelo , Jennifer L. Ross

Swimming organisms in their natural habitat navigate through a wide array of geometries and chemical environments. Interaction with the boundaries is ubiquitous and can significantly modify the swimming characteristics of the organism as…

Fluid Dynamics · Physics 2010-12-23 Saikat Jana , Soong Ho Um , Sunghwan Jung