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The translocation of a short DNA fragment through a nanopore is addressed when the perforated membrane contains an embedded electrode. Accurate numerical solutions of the coupled Poisson, Nernst-Planck, and Stokes equations for a realistic,…

Soft Condensed Matter · Physics 2017-06-29 Thomas Töws , Peter Reimann

A deep understanding of the correlation between electronic and mechanical degrees of freedom is crucial to the development of quantum devices in a nanoelectromechanical system (NEMS). In this work, we first establish a fully quantum…

Mesoscale and Nanoscale Physics · Physics 2025-05-14 Chengjie Wu , Yi Ding , Yiying Yan , Yuguo Su , Elijah Omollo Ayieta , Slobodan Radošević , Georg Engelhardt , Gernot Schaller , JunYan Luo

Negative differential conductance (NDC) is expected to be an essential property to realize fast switching in future electronic devices. We here present a thorough analysis on electron transportability of a simple atomic-scale model…

Materials Science · Physics 2009-11-07 Shigeru Tsukamoto , Masakazu Aono , Kikuji Hirose

Nanoscale molecular systems such as DNA require an atomistic quantum treatment to accurately capture their electrical properties, owing to their small dimensions. A central challenge in modeling transport through these systems is the…

Other Condensed Matter · Physics 2026-03-09 Hashem Mohammad , M. P. Anantram

We studied the electrical conductivity of DNA samples as function of the number of DNA molecules. We showed that the insulating gap (no current at low voltage) increases from ~1-2 V for bundles and large ropes to ~4-7 V for few DNA…

Soft Condensed Matter · Physics 2007-05-23 Thomas Heim , Dominique Deresemes , Dominique Vuillaume

Charge diffusion through desoxyribonucleic acid (DNA) is a physico-chemical phenomenon that on the one hand is being explored for technological purposes, on the other hand is applied by nature for various informational processes in life.…

Biological Physics · Physics 2024-07-22 Mirko Rossini , Ole Ammerpohl , Reiner Siebert , Joachim Ankerhold

We investigate the influence of a dissipative environment which effectively comprises the effects of counterions and hydration shells, on the transport properties of short \DNA wires. Their electronic structure is captured by a…

Soft Condensed Matter · Physics 2007-05-23 R. Gutierrez , S. Mandal , G. Cuniberti

DNA strand displacement is a key reaction in DNA homologous recombination and DNA mismatch repair and is also heavily utilized in DNA-based computation and locomotion. Despite its ubiquity in science and engineering, sequence-dependent…

Biological Physics · Physics 2016-04-13 Bo Broadwater , Harold Kim

Recent experimental evidence shows that the pi-orbitals along the stacking of base pairs can facilitate the long-range charge transfer in DNA. Proton motion in the base pair hydrogen bonds has also been found to affect the transfer rate. To…

Materials Science · Physics 2009-11-10 Chun-Min Chang , A. H. Castro Neto , A. R. Bishop

Charge transfer can take place along double helical DNA over distances as long as 30 nanometers. However, given the active role of the thermal environment surrounding charge carriers in DNA, physical mechanisms driving the transfer process…

Mesoscale and Nanoscale Physics · Physics 2020-12-04 Roman Korol , Dvira Segal

Graphene nanogaps and nanopores show potential for the purpose of electrical DNA sequencing, in particular because single-base resolution appears to be readily achievable. Here, we evaluated from first principles the advantages of a nanogap…

Mesoscale and Nanoscale Physics · Physics 2013-07-29 Jariyanee Prasongkit , Anton Grigoriev , Biswarup Pathak , Rajeev Ahuja , Ralph H. Scheicher

In this work we numerically calculate the electric current through three kinds of DNA sequences (telomeric, \lambda-DNA, and p53-DNA) described by different heuristic models. A bias voltage is applied between two zig-zag edged graphene…

Mesoscale and Nanoscale Physics · Physics 2012-10-02 Carlos J. Páez , Peter A. Schulz , Neil Wilson , Rudolf A. Römer

In this work, charge transport (CT) properties of the p53 gene are numerically studied by the transfer matrix method, and using either single or double strand effective tight-binding models. A statistical analysis of the consequences of…

Genomics · Quantitative Biology 2007-10-10 Chi-Tin Shih , Rudolf A. Römer , Stephan Roche

We present a short review of various experiments that measure charge transfer and charge transport in DNA. Some general comments are made on the possible connection between 'chemistry-style' charge transfer experiments that probe…

Disordered Systems and Neural Networks · Physics 2009-11-10 N. P. Armitage , M. Briman , G. Gruner

We investigate the ionic current modulation in DNA nanopore translocation setups by numerically solving the electrokinetic mean-field equations for an idealized model. Specifically, we study the dependence of the ionic current on the…

Soft Condensed Matter · Physics 2021-10-13 Kai Szuttor , Patrick Kreissl , Christian Holm

A rapid and low-cost method to sequence DNA would usher in a revolution in medicine. We propose and theoretically show the feasibility of a protocol for sequencing based on the distributions of transverse electrical currents of…

Soft Condensed Matter · Physics 2015-06-25 Johan Lagerqvist , Michael Zwolak , Massimiliano Di Ventra

We investigate quantum tunneling of charge carriers through a periodic superlattice in twisted bilayer graphene (TBG) with rectangular potential barriers, including the presence of a defect, using a low-energy continuum model. Transmission…

Mesoscale and Nanoscale Physics · Physics 2026-01-08 Ayoub Bahlaoui , Youness Zahidi , Ahmed Naddami

Microscopic mechanisms of positive charge transfer in DNA remain unclear. A quantum state of electron hole in DNA is determined by the competition of the pi-stacking interaction $b$ sharing a charge between different base pairs and the…

Soft Condensed Matter · Physics 2008-06-06 Dmitry B. Uskov , Alexander L. Burin

Several recent experiments suggest that sharply bent DNA has a surprisingly high bending flexibility, but the cause of this flexibility is poorly understood. Although excitation of flexible defects can explain these results, whether such…

Biological Physics · Physics 2015-12-22 Peiwen Cong , Liang Dai , Hu Chen , Johan R. C. van der Maarel , Patrick S. Doyle , Jie Yan

This work aims at investigating the impact of DNA geometry, compaction and calculation chain on DNA break and chromosome aberration predictions for high charge and energy (HZE) ions, using the Monte Carlo codes Geant4-DNA, RITRACKS and…