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Frequency modulation by perturbation is the essential trait that differentiates limit cycle oscillators from phase oscillators. We studied networks of identical limit cycle oscillators whose frequencies are modulated sensitively by the…

Adaptation and Self-Organizing Systems · Physics 2015-05-13 Masashi Tachikawa

We present and discuss the results of an experimental analysis in the design of Boolean networks by means of genetic algorithms. A population of networks is evolved with the aim of finding a network such that the attractor it reaches is of…

Neural and Evolutionary Computing · Computer Science 2011-02-01 Andrea Roli , Cristian Arcaroli , Marco Lazzarini , Stefano Benedettini

Deterministic and stochastic Boolean network models are build for the dynamics of negative feedback loops of the p53 pathways. It is shown that the main function of the negative feedback in the p53 pathways is to keep p53 at a low steady…

Molecular Networks · Quantitative Biology 2009-04-16 Hao Ge , Min Qian

We study living neural networks by measuring the neurons' response to a global electrical stimulation. Neural connectivity is lowered by reducing the synaptic strength, chemically blocking neurotransmitter receptors. We use a…

Neurons and Cognition · Quantitative Biology 2010-07-30 Ilan Breskin , Jordi Soriano , Elisha Moses , Tsvi Tlusty

Phase separation within polymer networks plays a central role in shaping the structure and mechanics of both synthetic materials and living cells, including the formation of biomolecular condensates within cytoskeletal networks. Previous…

Soft Condensed Matter · Physics 2025-12-01 Takahiro Yokoyama , Yicheng Qiang , David Zwicker , Arash Nikoubashman

Interdependent networks are ubiquitous in our society, ranging from infrastructure to economics, and the study of their cascading behaviors using percolation theory has attracted much attention in the recent years. To analyze the…

Physics and Society · Physics 2015-02-06 Ling Feng , Christopher Pineda Monterola , Yanqing Hu

We investigate the evolution of Boolean networks subject to a selective pressure which favors robustness against noise, as a model of evolved genetic regulatory systems. By mapping the evolutionary process into a statistical ensemble and…

Disordered Systems and Neural Networks · Physics 2012-04-11 Tiago P. Peixoto

Biological systems operate under persistent noise, which can alter system states and induce transitions between attractors. Here, we study the attractor dynamics of Boolean networks focusing on the transitions between attractors induced by…

Molecular Networks · Quantitative Biology 2026-03-05 Byungjoon Min , Jeehye Choi , Reinhard Laubenbacher

The dynamics of gene regulatory networks is governed by the interaction between deterministic biochemical reactions and molecular noise. To understand how gene regulatory networks process information during cell state transitions, we study…

Molecular Networks · Quantitative Biology 2025-09-11 Miguel Ángel García-Ariza , Alessandro Bravetti , Pablo Padilla , J Roberto Romero-Arias

We study the effects of propagation delays on the stochastic dynamics of bumps in neural fields with multiple layers. In the absence of noise, each layer supports a stationary bump. Using linear stability analysis, we show that delayed…

Neurons and Cognition · Quantitative Biology 2015-06-23 Zachary P. Kilpatrick

Boolean variables are such that they take only values on $ \mathbb{Z}_2 \cong \left\{0, 1 \right\} $. \textit{NK}-Kauffman networks are dynamical deterministic systems of $ N $ Boolean functions that depend only on $ K \leq N $ Boolean…

Adaptation and Self-Organizing Systems · Physics 2014-04-14 Federico Zertuche

Networks of coupled phase oscillators are one of the most studied dynamical systems with numerous applications in physics, chemistry, biology, and engineering. Their behaviour is often characterized by the emergence of various partially…

Pattern Formation and Solitons · Physics 2026-02-27 Oleh E. Omel'chenko

This article examines the impact of Hamiltonian dynamics on the interaction graph of Boolean networks. Three types of dynamics are considered: maximum height, Hamiltonian cycle, and an intermediate dynamic between these two. The study…

Discrete Mathematics · Computer Science 2026-05-14 Arturo Zapata-Cortés , Julio Aracena

We investigate a generalized Kuramoto phase-oscillator model with Hebb-like couplings that evolve according to a stochastic differential equation on various topologies. Numerical simulations show that even with identical oscillators, there…

Statistical Mechanics · Physics 2014-04-15 A. Isakov , L. Mahadevan

We consider propagation models that describe the spreading of an attribute, called "damage", through the nodes of a random network. In some systems, the average fraction of nodes that remain undamaged vanishes in the large system limit, a…

Cellular Automata and Lattice Gases · Physics 2007-05-23 Björn Samuelsson , Joshua E. S. Socolar

The determination and classification of fixed points of large Boolean networks is addressed in terms of constraint satisfaction problem. We develop a general simplification scheme that, removing all those variables and functions belonging…

Disordered Systems and Neural Networks · Physics 2009-11-10 L. Correale , M. Leone , A. Pagnani , M. Weigt , R. Zecchina

Multiple dynamic pathways always exist in biological networks, but their robustness against internal fluctuations and relative stability have not been well recognized and carefully analyzed yet. Here we try to address these issues through…

Molecular Networks · Quantitative Biology 2015-11-27 Yongyi Guo , Zhiyi You , Min Qian , Hao Ge

Dynamical processes taking place on networks have received much attention in recent years, especially on various models of random graphs (including small world and scale free networks). They model a variety of phenomena, including the…

Probability · Mathematics 2007-05-23 Jonathan Rowe , Boris Mitavskiy

This paper presents the foundation for a decomposition theory for Boolean networks, a type of discrete dynamical system that has found a wide range of applications in the life sciences, engineering, and physics. Given a Boolean network…

Dynamical Systems · Mathematics 2022-06-10 Claus Kadelka , Reinhard Laubenbacher , David Murrugarra , Alan Veliz-Cuba , Matthew Wheeler

We study the dynamics of gene activities in relatively small size biological networks (up to a few tens of nodes), e.g. the activities of cell-cycle proteins during the mitotic cell-cycle progression. Using the framework of deterministic…

Molecular Networks · Quantitative Biology 2009-11-13 Gautier Stoll , Jacques Rougemont , Felix Naef