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Likelihood-based methods of statistical inference provide a useful general methodology that is appealing, as a straightforward asymptotic theory can be applied for their implementation. It is important to assess the relationships between…

Statistics Theory · Mathematics 2015-03-20 Thomas J. DiCiccio , Todd A. Kuffner , G. Alastair Young , Russell Zaretzki

When conducting large scale inference, such as genome-wide association studies or image analysis, nominal $p$-values are often adjusted to improve control over the family-wise error rate (FWER). When the majority of tests are null,…

Methodology · Statistics 2017-07-20 Sarah Fletcher Mercaldo , Jeffrey D. Blume

Large-scale multiple testing problems require the simultaneous assessment of many p-values. This paper compares several methods to assess the evidence in multiple binomial counts of p-values: the maximum of the binomial counts after…

Methodology · Statistics 2014-02-26 Guenther Walther

It is well known that there is no direct one-to-one relation between $p$-values and likelihood ratios or Bayes factors, since their relation crucially involves the sample size $n$. We investigate their (asymptotic) relation in a…

Statistics Theory · Mathematics 2026-03-23 Wouter Kager , Ronald Meester

This article gives a survey of the e-value, a statistical significance measure a.k.a. the evidence rendered by observational data, X, in support of a statistical hypothesis, H, or, the other way around, the epistemic value of H given X. The…

Methodology · Statistics 2020-04-29 Julio Michael Stern , Carlos Alberto de Braganca Pereira

Fisherian randomization inference is often dismissed as testing an uninteresting and implausible hypothesis: the sharp null of no effects whatsoever. We show that this view is overly narrow. Many randomization tests are also valid under a…

Methodology · Statistics 2017-09-22 Devin Caughey , Allan Dafoe , Luke Miratrix

Increasing accessibility of data to researchers makes it possible to conduct massive amounts of statistical testing. Rather than follow a carefully crafted set of scientific hypotheses with statistical analysis, researchers can now test…

Genomics · Quantitative Biology 2016-09-08 Olga A. Vsevolozhskaya , Chia-Ling Kuo , Gabriel Ruiz , Luda Diatchenko , Dmitri V. Zaykin

In this paper, we demonstrate that a new measure of evidence we developed called the Dempster-Shafer p-value which allow for insights and interpretations which retain most of the structure of the p-value while covering for some of the…

Methodology · Statistics 2024-02-28 Kentaro Hoffman , Kai Zhang , Tyler McCormick , Jan Hannig

In the hypothesis testing framework, p-value is often computed to determine rejection of the null hypothesis or not. On the other hand, Bayesian approaches typically compute the posterior probability of the null hypothesis to evaluate its…

Methodology · Statistics 2020-02-26 Guosheng Yin , Haolun Shi

Mathematics is a limited component of solutions to real-world problems, as it expresses only what is expected to be true if all our assumptions are correct, including implicit assumptions that are omnipresent and often incorrect.…

Methodology · Statistics 2023-09-14 Sander Greenland

Nurses should rely on the best evidence, but tend to struggle with statistics, impeding research integration into clinical practice. Statistical significance, a key concept in classical statistics, and its primary metric, the p-value, are…

Methodology · Statistics 2023-11-27 Christopher Holmberg

The concept of intrinsic credibility has been recently introduced to check the credibility of "out of the blue" findings without any prior support. A significant result is deemed intrinsically credible if it is in conflict with a sceptical…

Methodology · Statistics 2022-11-08 Leonhard Held

Many practical studies rely on hypothesis testing procedures applied to data sets with missing information. An important part of the analysis is to determine the impact of the missing data on the performance of the test, and this can be…

Methodology · Statistics 2011-02-15 Dan L. Nicolae , Xiao-Li Meng , Augustine Kong

Bayesian hypothesis testing is re-examined from the perspective of an a priori assessment of the test statistic distribution under the alternative. By assessing the distribution of an observable test statistic, rather than prior parameter…

Statistics Theory · Mathematics 2018-08-28 Hedibert F. Lopes , Nicholas G. Polson

High-dimensional statistical inference with general estimating equations are challenging and remain less explored. In this paper, we study two problems in the area: confidence set estimation for multiple components of the model parameters,…

Methodology · Statistics 2021-04-28 Jinyuan Chang , Song Xi Chen , Cheng Yong Tang , Tong Tong Wu

Deciding whether a model provides a good description of data is often based on a goodness-of-fit criterion summarized by a p-value. Although there is considerable confusion concerning the meaning of p-values, leading to their misuse, they…

Data Analysis, Statistics and Probability · Physics 2013-05-29 Frederik Beaujean , Allen Caldwell , Daniel Kollar , Kevin Kroeninger

This contribution to the debate on confidence limits focuses mostly on the case of measurements with `open likelihood', in the sense that it is defined in the text. I will show that, though a prior-free assessment of {\it confidence} is, in…

High Energy Physics - Experiment · Physics 2007-05-23 G. D'Agostini

We explain the concept of p-values presupposing only rudimentary probability theory. We also use the occasion to introduce the notion of p-function, so that p-values are values of a p-function. The explanation is restricted to the discrete…

Statistics Theory · Mathematics 2016-03-15 Yuri Gurevich , Vladimir Vovk

Attacks on the P-value are nothing new, but the recent attacks are increasingly more serious. They come from more mainstream sources, with widening targets such as a call to retire the significance testing altogether. While well meaning, I…

Other Statistics · Statistics 2022-01-11 Yudi Pawitan

Both the Bayes factor and the relative belief ratio satisfy the principle of evidence and so can be seen to be valid measures of statistical evidence. Certainly Bayes factors are regularly employed. The question then is: which of these…

Statistics Theory · Mathematics 2024-02-28 Luai Al-Labadi , Ayman Alzaatreh , Michael Evans
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