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A fundamental assumption of classical hypothesis testing is that the significance threshold $\alpha$ is chosen independently from the data. The validity of confidence intervals likewise relies on choosing $\alpha$ beforehand. We point out…

Applications · Statistics 2025-03-11 Jesse Hemerik , Nick W Koning

The main purpose of this paper is to introduce first a new family of empirical test statistics for testing a simple null hypothesis when the vector of parameters of interest are defined through a specific set of unbiased estimating…

Statistics Theory · Mathematics 2014-08-19 Narayanaswamy Balakrishnan , Nirian Martín , Leandro Pardo

Verifying that a statistically significant result is scientifically meaningful is not only good scientific practice, it is a natural way to control the Type I error rate. Here we introduce a novel extension of the p-value - a…

Methodology · Statistics 2018-07-04 Jeffrey D. Blume , Lucy DAgostino McGowan , William D. Dupont , Robert A. Greevy

We point out that the traditional notion of test statistic is too narrow, and we propose a natural generalization that is arguably maximal. The study is restricted to simple statistical hypotheses.

Methodology · Statistics 2020-01-07 Yuri Gurevich , Vladimir Vovk

I present a critique of the methods used in a typical paper. This leads to three broad conclusions about the conventional use of statistical methods. First, results are often reported in an unnecessarily obscure manner. Second, the null…

Applications · Statistics 2013-03-05 Michael Wood

The small sample universal hypothesis testing problem is investigated in this paper, in which the number of samples $n$ is smaller than the number of possible outcomes $m$. The goal of this work is to find an appropriate criterion to…

Statistics Theory · Mathematics 2014-12-30 Dayu Huang , Sean Meyn

We are concerned with testing replicability hypotheses for many endpoints simultaneously. This constitutes a multiple test problem with composite null hypotheses. Traditional $p$-values, which are computed under least favourable parameter…

Methodology · Statistics 2020-02-26 Anh-Tuan Hoang , Thorsten Dickhaus

Research in Sports Sciences is supported often by inferences based on the declaration of the value of the statistic statistically significant or nonsignificant on the bases of a P value derived from a null-hypothesis test. Taking into…

Applications · Statistics 2018-02-09 Rui Marcelino , Bruno Natale Pasquarelli , Jaime Sampaio

Testing to see whether a given data set comes from some specified distribution is among the oldest types of problems in Statistics. Many such tests have been developed and their performance studied. The general result has been that while a…

Applications · Statistics 2020-12-07 Wolfgang Rolke

In applied settings, tests of hypothesis where a nuisance parameter is only identifiable under the alternative often reduces into one of Testing One Hypothesis Multiple times (TOHM). Specifically, a fine discretization of the space of the…

Methodology · Statistics 2022-04-06 Sara Algeri , David A. van Dyk

Statistical analysis is used throughout biomedical research and elsewhere to assess strength of evidence. We have previously argued that typical outcome statistics (including p-values and maximum likelihood ratios) have poor…

Statistics Theory · Mathematics 2013-10-02 V. J. Vieland , J. Das , S. E. Hodge , S. -C. Seok

We study a large-scale one-sided multiple testing problem in which test statistics follow normal distributions with unit variance, and the goal is to identify signals with positive mean effects. A conventional approach is to compute…

Methodology · Statistics 2026-05-15 Kwangok Seo , Johan Lim , Hyungwon Choi , Jaesik Jeong

A new formulation for the proportion of true null hypotheses $(\pi_0)$, based on the sum of all $p$-values and the average of expected $p$-value under the false null hypotheses has been proposed in the current work. This formulation of the…

Statistics Theory · Mathematics 2020-04-07 Aniket Biswas

The controversy about statistical significance vs. scientific relevance is more than 100 years old. But still nowadays null hypothesis significance testing is considered as gold standard in many empirical fields from economics and social…

Applications · Statistics 2022-11-23 Uwe Hassler

Researchers often misinterpret and misrepresent statistical outputs. This abuse has led to a large literature on modification or replacement of testing thresholds and $P$-values with confidence intervals, Bayes factors, and other devices.…

Methodology · Statistics 2020-10-02 Zad Rafi , Sander Greenland

A pervasive issue in statistical hypothesis testing is that the reported $p$-values are biased downward by data "peeking" -- the practice of reporting only progressively extreme values of the test statistic as more data samples are…

Statistics Theory · Mathematics 2020-11-04 Akshay Balsubramani

Statistical hypothesis tests typically use prespecified sample sizes, yet data often arrive sequentially. Interim analyses invalidate classical error guarantees, while existing sequential methods require rigid testing preschedules or incur…

Methodology · Statistics 2026-02-17 Chris Holmes , Stephen Walker

Statistical hypothesis testing is the central method to demarcate scientific theories in both exploratory and inferential analyses. However, whether this method befits such purpose remains a matter of debate. Established approaches to…

Data Analysis, Statistics and Probability · Physics 2024-10-29 Orestis Loukas , Ho-Ryun Chung

Since its debut in the 18th century, the P-value has been an important part of hypothesis testing-based scientific discoveries. As the statistical engine accelerates, questions are beginning to be raised, asking to what extent scientific…

The validity of classical hypothesis testing requires the significance level $\alpha$ be fixed before any statistical analysis takes place. This is a stringent requirement. For instance, it prohibits updating $\alpha$ during (or after) an…

Statistics Theory · Mathematics 2026-01-21 Ben Chugg , Tyron Lardy , Aaditya Ramdas , Peter Grünwald