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DNA data storage systems encode digital data into DNA strands, enabling dense and durable storage. Efficient data retrieval depends on coverage depth, a key performance metric. We study the random access coverage depth problem and focus on…

Information Theory · Computer Science 2025-07-29 Şeyma Bodur , Stefano Lia , Hiram H. López , Rati Ludhani , Alberto Ravagnani , Lisa Seccia

We perform geometrization of genetics by representing genetic information by points of the 4-adic {\it information space.} By well known theorem of number theory this space can also be represented as the 2-adic space. The process of…

Other Quantitative Biology · Quantitative Biology 2007-05-23 Andrei Khrennikov

This work concerns formal descriptions of DNA code properties, and builds on previous work on transducer descriptions of classic code properties and on trajectory descriptions of DNA code properties. This line of research allows us to give…

Formal Languages and Automata Theory · Computer Science 2015-03-03 Lila Kari , Stavros Konstantinidis , Steffen Kopecki

The genetic information that dictates the structure and function of all life forms is encoded in the DNA. In 1953, Watson and Crick first presented the double helical structure of a DNA molecule. Their findings unearthed the desire to…

Genomics · Quantitative Biology 2023-05-16 Olaitan Akintunde , Trichina Tucker , Valerie J. Carabetta

DNA emerges as a promising medium for the exponential growth of digital data due to its density and durability. This study extends recent research by addressing the \emph{coverage depth problem} in practical scenarios, exploring optimal…

Information Theory · Computer Science 2024-02-01 Hadas Abraham , Rayn Gabrys , Eitan Yaakobi

DNA, with remarkable properties of high density, durability, and replicability, is one of the most appealing storage media. Emerging DNA storage technologies use composite DNA letters, where information is represented by probability…

Information Theory · Computer Science 2025-03-26 Wenkai Zhang , Zhiying Wang

The surface code is the most studied error-correcting code thanks to its high threshold, simple decoding, and locality in two dimensions (2D). A key component of any code is its encoding circuit, which maps an unencoded state to the…

Quantum Physics · Physics 2025-09-15 Jahan Claes

In the global challenge of understanding and characterizing biodiversity, short species-specific genomic sequences known as DNA barcodes play a critical role, enabling fine-grained comparisons among organisms within the same kingdom of…

The use of deep neural network for decoding error control code will encounter two problems, namely, the high-precision requirements of the error control code and the complexity of the neural network due to the long code. In this paper, a…

Signal Processing · Electrical Eng. & Systems 2019-01-01 Jiang Xiaobo , Zhang Fang , Zeng Zhen

Composite DNA is a recent novel method to increase the information capacity of DNA-based data storage above the theoretical limit of 2 bits/symbol. In this method, every composite symbol does not store a single DNA nucleotide but a mixture…

Information Theory · Computer Science 2025-01-22 Tuan Thanh Nguyen , Chen Wang , Kui Cai , Yiwei Zhang , Zohar Yakhini

Recent advances in next-generation sequencing technologies have facilitated the use of deoxyribonucleic acid (DNA) as a novel covert channels in steganography. There are various methods that exist in other domains to detect hidden messages…

Machine Learning · Computer Science 2018-10-08 Ho Bae , Byunghan Lee , Sunyoung Kwon , Sungroh Yoon

To increase the information capacity of DNA storage, composite DNA letters were introduced. We propose a novel channel model for composite DNA in which composite sequences are decomposed into ordered standard non-composite sequences. The…

Information Theory · Computer Science 2025-10-31 Besart Dollma , Ohad Elishco , Eitan Yaakobi

Synthetic DNA approaches 227.5 exabytes per gram of storage density with stability over millennial timescales. Realising this capacity requires error-correction codes that recover data from substantial synthesis and sequencing errors.…

Information Theory · Computer Science 2026-04-23 James L. Banal

Device-to-device (D2D) aided beamforming for coded caching is considered in finite signal-to-noise ratio regime. A novel beamforming scheme is proposed where the local cache content exchange among nearby users is exploited. The transmission…

Information Theory · Computer Science 2019-05-15 Hamidreza Bakhshzad Mahmoodi , Jarkko Kaleva , Seyed Pooya Shariatpanahi , Babak Khalaj , Antti Tölli

Biomolecular computation has emerged as an important area of computer science research due to its high information density, immense parallelism opportunity along with potential applications in cryptography, genetic engineering and…

Formal Languages and Automata Theory · Computer Science 2022-06-07 Anupam Chattopadhyay , Arnab Chakrabarti

DNA adsorption on solid or liquid surfaces is a topic of broad fundamental and applied interest. Here we study by x-ray reflectivity the adsorption of monodisperse double-stranded DNA molecules a positively-charged surface, obtained through…

Soft Condensed Matter · Physics 2008-09-29 Carine Douarche , Robert Cortès , Steven J. Roser , Jean-Louis Sikorav , Alan Braslau

We study the combination of two recent coding approaches, in the context of DNA based data storage. Composite DNA alphabets leverage properties of the DNA synthesis and sequencing process. A composite symbol does not represent a single…

Information Theory · Computer Science 2026-05-20 Tomer Cohen , Eitan Yaakobi , Zohar Yakhini

Reverse engineering of binary executables is a critical problem in the computer security domain. On the one hand, malicious parties may recover interpretable source codes from the software products to gain commercial advantages. On the…

Programming Languages · Computer Science 2019-07-01 Cheng Fu , Huili Chen , Haolan Liu , Xinyun Chen , Yuandong Tian , Farinaz Koushanfar , Jishen Zhao

Decoding algorithms based on approximate tensor network contraction have proven tremendously successful in decoding 2D local quantum codes such as surface/toric codes and color codes, effectively achieving optimal decoding accuracy. In this…

Quantum Physics · Physics 2024-10-10 Christophe Piveteau , Christopher T. Chubb , Joseph M. Renes

Learning binary representation is essential to large-scale computer vision tasks. Most existing algorithms require a separate quantization constraint to learn effective hashing functions. In this work, we present Direct Binary Embedding…

Computer Vision and Pattern Recognition · Computer Science 2017-06-06 Liu Liu , Alireza Rahimpour , Ali Taalimi , Hairong Qi
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